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Diabetes Is Linked To This Invasive Gut Bacteria


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2017 Jun 16, 6:55am   2,121 views  14 comments

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New research suggests the chronic condition may also be linked to bacteria attacking the mucus lining of the colon.

Researchers wanted to see if invading bacteria in the epithelium, a mucus-lined cellular covering in the intestinal tract, would increase inflammation, which interferes with how the body normally deals with insulin. This could lead to metabolic diseases such as type 2 diabetes. They collected samples from patients' colonoscopies, and discovered that diabetes is linked with bacteria that penetrate the mucus lining, according to a news release.

Previous research has indicated that changes in bacteria are associated with a range of diseases, including type 2 diabetes, but the mechanisms remained unknown. Studies on mouse models have also shown how bacteria can invade the epithelium, promoting inflammation, study author Andrew Gewirtz explained in the release.

“Now we've shown that this is also a feature of metabolic disease in humans, specifically type 2 diabetics," who have harmful bacteria invading the intestinal tract, Gewirtz said.

The study, published in the journal Cellular and Molecular Gastroenterology and Hepatology, involved samples from 42 participants who were at least 21 years old and had diabetes, but no other major health problems. They were all scheduled to undergo colonoscopy to screen for colon cancer at Veteran’s Administration Hospital in Atlanta. The researchers gathered the patient’s health history through medical records and interviews. During their procedure, samples were taken from the colon to be analyzed.

After looking at the specimens, the researchers concluded that "microbiota encroachment" is related to abnormal blood sugar levels, also known as insulin-resistance-associated dysglycemia, in people. Type 2 diabetes, which is the most common form of diabetes, occurs when the body begins to resist insulin.

The scientists plan to conduct follow-up research to better understand the type of bacteria present, so they can create treatments that may stop the bacteria from invading the colon.

The findings have caught the eyes of other researchers not involved with this study.

http://www.ibtimes.com/diabetes-linked-invasive-gut-bacteria-2547563?utm_source=internal&utm_campaign=most_read&utm_medium=most_read1

Related: https://patrick.net/1289828/2016-03-10-are-you-pre-diabetic-46-of-california-adults-are

#Diabetes #Medicine #Science

Comments 1 - 14 of 14        Search these comments

1   Shaman   2017 Jun 16, 8:12am  

The cultivation of a healthy gut microbiome is coming to be understood as essential for general health. It contributes to a wide spectrum of health points including healthy weight and healthy immune response.
That is why artificial sweeteners can cause so much damage, as they harm helpful gut bacteria and promote the growth of harmful bacteria. It's through mechanisms such as the article explains, that these harmful bacteria can contribute to or cause diabetes.

To give a real (if specific) example: my father was diagnosed with diabetes II about two years ago. His blood sugars had been out of control for years at dangerous levels (or so we believe) causing cataracts that made him nearly blind. He only got the diagnosis of diabetes when he went for surgery to correct the cataracts. He went on a healthy diet immediately (prescribed by my dietician wife), lost about fifty pounds, and today he sees fine and his condition has been downgraded to "prediabetic." He takes no insulin.

2   Automan Empire   2017 Jun 16, 8:17am  

The stupid amount of sugar, HFCS, and sweeteners consumed per capita is no help. Could dietary trends promote the gut flora described, better than historical diets?

I had a GF with diabetes, knew it was time to gather my things when I spotted her trying to conceal 4 huge homemade cookies and her insulin kit in one hand. ಠ_ಠ

This is an interesting study; if it pans out this is bigger than discovering Helicobacter Pyroli's role in stomach ulcers!

3   justme   2017 Jun 16, 9:53am  

Quigley says

That is why artificial sweeteners can cause so much damage, as they harm helpful gut bacteria and promote the growth of harmful bacteria. (ADDED) It's through mechanisms such as the article explains, that these harmful bacteria can contribute to or cause diabetes.

There has certainly been speculation that artificial sweeteners might have bad digestive effects, but the study quoted in this post is about sugar, not artificial sweeteners.

4   justme   2017 Jun 16, 9:53am  

Automan Empire says

This is an interesting study; if it pans out this is bigger than discovering Helicobacter Pyroli's role in stomach ulcers!

Indeed. That was a big one. Affected a relative of mine, and a neighbor, too.

5   HEY YOU   2017 Jun 16, 10:21am  

Automan Empire says

The stupid amount of sugar, HFCS, and sweeteners consumed per capita is no help. Could dietary trends promote the gut flora described, better than historical diets?

Sugar is American white powder. Heat it & chase the dragon.

Wonder if all the pollutants,in the environment, have any affect on the human body?
I can avoid sweeteners.

6   Shaman   2017 Jun 16, 10:24am  

justme says

There has certainly been speculation that artificial sweeteners might have bad digestive effects, but the study quoted in this post is about sugar, not artificial sweeteners.

Nice use of selective quoting to make your asinine point. If you'd included the VERY NEXT SENTENCE in your quote, your entire argument would have been null. Or if you'd read the OP. I don't have time for this crap.

7   justme   2017 Jun 16, 10:31am  

Quigley is sore because I pointed out he was subscribing to false flag propaganda in another thread. It's ok, Quigley. I will include your VERY NEXT SENTENCE in the quote above so that people can see that your speculation is still just speculation.

8   clambo   2018 Jun 21, 6:11pm  

Diabetes in some cases is also attributed to feeding your gut massive quantities of spaghetti, pizza, beer, donuts, etc.
9   rocketjoe79   2018 Jun 22, 4:11pm  

clambo says
Diabetes in some cases is also attributed to feeding your gut massive quantities of spaghetti, pizza, beer, donuts, etc.


I try to avoid white stuff: Sugar, pasta, potatoes and rice. I'm a meatatarian, so this isn't much of a problem.
10   HeadSet   2018 Jun 22, 4:16pm  

Diabetes defeated by diet: How new fresh-food prescriptions are beating pricey drugs

Yep, especially Type 2 diabetes. Type 2 diabetes really should be relabeled as "getting fat" onset diabetes.
11   lostand confused   2018 Jun 22, 4:17pm  

clambo says
Diabetes in some cases is also attributed to feeding your gut massive quantities of spaghetti, pizza, beer, donuts, etc.

Yes and no. I know quite a few people with diabetes 2.-family and otherwise. Some are the proverbial fatty with no excersie. Some exercise, rail thin and watch their calories and exercise. This study makes a lot of sense. But one thing I find common is diet and exercise seems to help keep it in control. But this gut bacteria might make sense.
12   Automan Empire   2018 Jun 22, 4:59pm  

Imagine suffering from diabetes for years/decades, only to realize what you needed all along was a SHIT TRANSPLANT?
13   HeadSet   2018 Jun 22, 5:13pm  

Automan Empire says
Imagine suffering from diabetes for years/decades, only to realize what you needed all along was a SHIT TRANSPLANT?


Which means that an individual with the right bacteria in his gut could be a donor. Imagine being paid to eat a high fiber diet and sell your crap. Would that be part of the "gig" economy?
14   RWSGFY   2018 Jun 22, 5:25pm  

Automan Empire says
Imagine suffering from diabetes for years/decades, only to realize what you needed all along was a SHIT TRANSPLANT?


Nah, they will just kill the fucking thing with an antibiotic, just like they deal with that helicobacter thing.

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