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Efficacy of hydroxychloroquine against Wuhan virus


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2020 Mar 21, 10:47am   11,526 views  290 comments

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1   Tenpoundbass   2020 Mar 21, 12:14pm  

The truth will be known by Friday of next week.

If they come back 100%, we can expect Trump to tell everyone healthy enough(99.99987% not affected) of the nation, to get back to work by the next Monday.

It could be why Trump is going full hand on all of the Social perks.

First to show America, that Social nets are for everyone not just a protected class. And if you're going to do it, then do it sensible and right.
Second to allow the Democrats fight tooth and nail to block it(even though it will have a 89% approval).

By time all of that is realized, Trump wont have to cut all of those checks. People will be back to work, the dying will be cured. Then he can focus on setting up industry and manufacturing, now that our interest are piqued.

the third reason, getting back to work is always better than Social handouts, and stores without toilet paper.
2   MisdemeanorRebel   2020 Mar 21, 12:19pm  

Tenpoundbass says
The truth will be known by Friday of next week.

If they come back 100%, we can expect Trump to tell everyone healthy enough(99.99987% not affected) of the nation, to get back to work by the next Monday.

It could be why Trump is going full hand on all of the Social perks.


I like this scenario.

Your lips -> God's Ears.
3   Patrick   2020 Mar 21, 12:48pm  

What it comes down to is doctors themselves seeing whether hydroxychloroquine and azithromycin are effective or not.

Tin foil hat time: what if China discovered that the cure really is that simple, and just decided to let the rest of the world sink into panic and economic depression? Maybe that is really how their death rate fell so quickly, and not really just the lockdown.

4   Patrick   2020 Mar 21, 12:51pm  

And even though azithromycin is an antibiotic, intended to work only against bacteria, there is evidence that it has anti-viral effects too:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923851/
6   Patrick   2020 Mar 23, 1:00pm  

Korea recommends that doctors consider hydroxychloroquine in bad cases:

http://m.koreabiomed.com/news/articleView.html?idxno=7428

If more than 10 days have passed since the onset of the illness and the symptoms are mild, physicians do not have to start an antiviral medication, the task force said.

However, if patients are old or have underlying conditions with serious symptoms, physicians should consider an antiviral treatment. If they decide to use the antiviral therapy, they should start the administration as soon as possible, the task force noted.

For the antiviral treatment, the doctors recommended lopinavir 400mg/ritonavir 100mg (Kaletra two tablets, twice a day) or chloroquine 500mg orally per day.

As chloroquine is not available in Korea, doctors could consider hydroxychloroquine 400mg orally per day, they said. There is no evidence that using lopinavir/ritonavir with chloroquine is more effective than monotherapies, they added.
7   Patrick   2020 Mar 23, 1:03pm  

NY State is taking chloroquine seriously enough to test it:

https://nationalinterest.org/blog/buzz/new-york-test-hydroxychloroquine-treatment-coronavirus-136047

New York Gov. Andrew Cuomo said Sunday that his state is set to begin clinical trials this week for a malaria drug that President Donald Trump has touted as a possible treatment for coronavirus.

“The president is optimistic about these drugs, and we are all optimistic that it could work,” Cuomo said at a daily press conference in Albany.

Cuomo said that state health officials have procured 750,000 doses of the malaria drug chloroquine; 70,000 doses of its derivative, hydroxychloroquine; and 10,000 doses of the antibiotic Zithromax to use in trials set to begin Tuesday.
8   Patrick   2020 Mar 23, 1:09pm  

Chinese scientific article:

https://www.ncbi.nlm.nih.gov/pubmed/32075365

Previous studies have shown that chloroquine phosphate (chloroquine) had a wide range of antiviral effects, including anti-coronavirus. Here we found that treating the patients diagnosed as novel coronavirus pneumonia with chloroquine might improve the success rate of treatment, shorten hospital stay and improve patient outcome. In order to guide and regulate the use of chloroquine in patients with novel coronavirus pneumonia, the multicenter collaboration group of Department of Science and Technology of Guangdong Province and Health Commission of Guangdong Province for chloroquine in the treatment of novel coronavirus pneumonia developed this expert consensus after extensive discussion. It recommended chloroquine phosphate tablet, 500mg twice per day for 10 days for patients diagnosed as mild, moderate and severe cases of novel coronavirus pneumonia and without contraindications to chloroquine.
10   mell   2020 Mar 23, 1:32pm  

To me this all indicates it's working -Trump should continue the pressure to get as much of those meds to patients as possible and as fast as possible, fuck red tape. Trump is good at removing red tape if he can get that done he'd be hero.
11   Tenpoundbass   2020 Mar 23, 1:59pm  

I'm beginning to think I was right. When I said it probably cures way more than just Malaria or CV19.
Look at the full on attack our Medical system has been assaulting chlorioquine phosphate and quinine.
They worry about rare mild effects, while every drug on the market today has potential for long term side effects. My mom takes a 20 pill cocktail everyday. One is for the side effects of another pill she takes for something else. It's sickening.
If our medical system, had any plans on testing the effectiveness they would have done it long by now. It seems they've doubled down on suppressing it than touting it's effectiveness. They don't even allow it for Malaria now, unless you're in bad shape.

https://www.livescience.com/chloroquine-coronavirus-treatment.html
12   EBGuy   2020 Mar 23, 7:22pm  

Trout, Please stay away from the pet shop and limit your gin and tonic intake!
March 23 (Reuters) - An Arizona man has died and his wife is in critical condition after they ingested chloroquine phosphate - an aquarium cleaning product similar to drugs that have been named by President Trump as potential treatments for coronavirus infection.
13   Tenpoundbass   2020 Mar 23, 9:45pm  

EBGuy says
Trout, Please stay away from the pet shop and limit your gin and tonic intake!


I googled that story and it only came up with propaganda fake news sites. The Fake News MSN wouldn't even touch it.
Than I saw this.

https://www.thegatewaypundit.com/2020/03/fake-news-hacks-claim-man-died-after-ingesting-chloroquine-because-of-trump-leaves-out-the-fact-he-actually-drank-fish-tank-cleaner/
14   Tenpoundbass   2020 Mar 23, 9:48pm  

EBGuy says
Trout, Please stay away from the pet shop and limit your gin and tonic intake!


350 people cured 100% success rate. By Friday the FDA, CDC, WHO, and the Obamacare System are going to have to answer a lot of tough questions about why they were stonewalling the cure.
https://www.thegatewaypundit.com/2020/03/stunning-ny-doctor-vladimir-zelenko-finds-100-success-rate-in-350-patients-using-hydroxychloroquine-with-z-paks-video/
15   WookieMan   2020 Mar 23, 9:59pm  

APOCALYPSEFUCKisShostikovitch says
The shit is caustic. It works but it will make you deaf and boil your retinas

Aren't most people with this deaf anyway? Likely with shit vision? If it keeps them alive and the families happy that their fat fuck, diabetic grandpa can live another few months, who cares how bad it is for you. The alternative is killing otherwise healthy people and overwhelming the healthcare system with people that should live because of minor and standard illnesses.
16   Tenpoundbass   2020 Mar 23, 10:06pm  

APOCALYPSEFUCKisShostikovitch says
The shit is caustic. It works but it will make you deaf and boil your retinas.

If I were sick and had choices, I'd be asking about them long before I'd consider this stuff.


Sounds like Fear mongering hype to me, that's not what the survivors it has cured has been saying.
17   Patrick   2020 Mar 23, 10:20pm  

It is, in Korea at least.
18   AD   2020 Mar 24, 6:32am  

Patrick says
Tin foil hat time: what if China discovered that the cure really is that simple, and just decided to let the rest of the world sink into panic and economic depression? Maybe that is really how their death rate fell so quickly, and not really just the lockdown.


Exactly Patrick ! I have read in the mainstream media how China did not allow WHO access to information like the possible origin of the virus and the Chinese treatment plans.

Of course the Left Wing media (CNN, NY Times, NBC, etc.) went on the defensive it was not because of some sinister plot but because the "pride" of the Chinese not wanting help from outside.

I am willing to state the ChiComs would exploit the US media like the CNN's and NBC's to get them to fool enough of the American public into thinking this, then realizing it was not "pride" but actually their "sinister plot" (as part of their 100 Year Plan described by author Michael Pilsbury) to hurt the western world.
19   mell   2020 Mar 24, 7:33am  

It's not a light drug but the main side effects to look out for are QT interval prolongation / irregular heart rhythm and heavy dizzyness/fainting. All the other side effects are manageable and revert quickly. If your heart can handle it you should be good to take it. They should def treat all the serious to critical patients with it. No excuse not to.
20   Tenpoundbass   2020 Mar 24, 7:38am  

I would rather die quickly from an irregular heart beat than to suffer suffocating to death. Which is what happens with CV.
21   Patrick   2020 Mar 24, 8:38am  

https://www.wsj.com/articles/these-drugs-are-helping-our-coronavirus-patients-11584899438


In 2005, a Centers for Disease Control and Prevention study showed that chloroquine, an analogue, could block a virus from penetrating a cell if administered before exposure. If tissue had already been infected, the drug inhibited the virus.

On March 9 a team of researchers in China published results showing hydroxychloroquine was effective against the 2019 coronavirus in a test tube. The authors suggested a five-day, 12-pill treatment for Covid-19: two 200-milligram tablets twice a day on the first day followed by one tablet twice a day for four more days.

A more recent French study used the drug in combination with azithromycin. Most Americans know azithromycin as the brand name Zithromax Z-Pak, prescribed for upper respiratory infections. The Z-Pak alone doesn’t appear to help fight Covid-19, and the findings of combination treatment are preliminary. ...

One lesson that should inform the U.S. approach: Use this treatment cocktail early, and don’t wait until a patient is on a ventilator in the intensive-care unit.

A couple of careful studies of hydroxychloroquine are in progress, but the results may take weeks or longer. Infectious-disease experts are already using hydroxychloroquine clinically with some success.
22   WookieMan   2020 Mar 24, 8:40am  

Tenpoundbass says
I would rather die quickly from an irregular heart beat than to suffer suffocating to death. Which is what happens with CV.

#amen. My dad had lung cancer before he later got liver cancer. He said the lung was substantially worse mentally and physically. Wanting and trying to gasp for air is something I think most people don't understand unless you have legit heavy asthma or other major respiratory issues. So yeah, if I'm already on a ventilator, toss me some heart attack drugs that potentially could allow me to fucking breath and stay alive.
23   Patrick   2020 Mar 24, 8:52pm  

https://www.ncbi.nlm.nih.gov/pubmed/32150618

RESULTS:
Hydroxychloroquine (EC50=0.72 μM) was found to be more potent than chloroquine (EC50=5.47 μM) in vitro. Based on PBPK models results, a loading dose of 400 mg twice daily of hydroxychloroquine sulfate given orally, followed by a maintenance dose of 200 mg given twice daily for 4 days is recommended for SARS-CoV-2 infection, as it reached three times the potency of chloroquine phosphate when given 500 mg twice daily 5 days in advance.


From 9th of March.
24   Tenpoundbass   2020 Mar 24, 9:20pm  

No Way Jose, Trump can't end this global panic just like that. Just who does he think he is, this took years of preparations and many Globalist retreats to put this together.

These guys really are such creeps.

https://www.thegatewaypundit.com/2020/03/nevadas-democrat-governor-issues-emergency-order-barring-use-of-anti-malaria-drugs-for-coronavirus-patients/

Nevada’s Democrat Governor Issues Emergency Order Barring Use of Anti-Malaria Drugs For Coronavirus Patients

Nevada’s Governor Steve Sisolak (D) on Tuesday issued an emergency order barring the use of anti-malaria drugs such as chloroquine for Coronavirus patients.

Last week Sisolak shut down casinos and only kept open essential businesses like grocery stores and health care facilities.

In addition to barring the use of chloroquine for Coronavirus patients on Tuesday, Nevada’s governor also banned social gatherings of more than 10 people.
25   Patrick   2020 Mar 24, 9:54pm  

The insane levels of hate for Trump might lead lots of people to refuse to take any drug he said might work, just because Trump said it.

Hmmm. Kind of a self-solving problem.
26   Ceffer   2020 Mar 25, 2:57am  

If you are going to murder somebody and blame it on Coronavirus, whether it be for life insurance, cheapie divorce, or hatred/malice/jealousy, you better get cranking before it is too late.
27   Tenpoundbass   2020 Mar 25, 8:07am  

APOCALYPSEFUCKsaysPUTFACEHERE says
Wow. It's not first line but someone breathing pink mud has nothing to lose.


Nobody in the world has needed to die from this since at least last Friday.
The truth is, humans need to combat these colds and flues to build up our immune system. Some people's are stronger than others.
Most of the population got it or will get it and not think it's anything more than a smokers cough.
If we gave out medicine to everyone that contracts it, even VAX it into extinction, and don't keep our immune systems exercised and taxed. Then eventually the big one will come a long that kills millions like they keep hyping and portraying this nothing burger in the scheme of things. Unless you're coughing pink mud, then it's a pandemic. But that's only for .000001% of the population.

Just because it cures it, doesn't mean everyone that has it should take it. Just the bad cases, they shouldn't even have to stick a breathing tube down someone's throat. That's the point where it should be considered. Not a second before.

These self interested bastards, want to wait until we come up with a Vax then demand we(Those of us healthy enough it didn't give us symptoms) all get it. Meanwhile that wont do shit for those in ICU that wont make it until tomorrow.

So much lies and deceit, I can only imagine this Trump dragging our FDA Swamp out into the limelight so we can all get a good look at the hideous creatures that lurk there.
28   Shaman   2020 Mar 25, 8:15am  

The DEMOCRAT Governor of Nevada has issued an order BANNING the use of hydroxychloroquine for Covid-19.
Something something hoarding whatever. This order makes zero sense and may lead to unnecessary deaths.
Stupid old fuck I hope he gets it.

https://www.breitbart.com/politics/2020/03/25/nolte-nevadas-democrat-governor-outlaws-antimalarial-drugs-for-coronavirus-sufferers/
29   CBOEtrader   2020 Mar 25, 8:20am  

Shaman says
The DEMOCRAT Governor of Nevada has issued an order BANNING the use of hydroxychloroquine for Covid-19.
Something something hoarding whatever. This order makes zero sense and may lead to unnecessary deaths.
Stupid old fuck I hope he gets it.

https://www.breitbart.com/politics/2020/03/25/nolte-nevadas-democrat-governor-outlaws-antimalarial-drugs-for-coronavirus-sufferers/


TDS? Wtf is going on w this?
30   Heraclitusstudent   2020 Mar 25, 8:31am  

New study casts doubt on hyrdoxychloroquine’s effectiveness in treating coronavirus
https://techcrunch.com/2020/03/25/new-study-casts-doubt-on-hyrdoxychloroquines-effectiveness-in-treating-coronavirus/

a new small-scale study by researchers in China indicates that the antimalarial drug hydroxychloroquine actually isn’t any more effective than standard, existing best practice for conventional care of patients with the virus.
31   Shaman   2020 Mar 25, 8:34am  

Heraclitusstudent says
New study casts doubt on hyrdoxychloroquine’s effectiveness in treating coronavirus
https://techcrunch.com/2020/03/25/new-study-casts-doubt-on-hyrdoxychloroquines-effectiveness-in-treating-coronavirus/


1)A 30 patient “study” is far too small to constitute anything more than an anecdote. Certainly not a scientific conclusion
2)No information was given on ages of patients involved (which could skew the study tremendously if unequal among the test and control groups). If they put a bunch of 35 year olds in the control group and a bunch of 70 year olds in the test group, they’ll get the numbers they want without ever putting anything to the test.
3)It was done in communist China which as we all know is ASSHOE!!

Your Post is worthless.
32   Heraclitusstudent   2020 Mar 25, 8:37am  

Shaman says
1)A 30 patient “study” is far too small to constitute anything more than an anecdote. Certainly not a scientific conclusion

Ok so the study done in France that showed it's usefulness is also anecdote.
Everything so far about this drug is anecdote, and if my post was useless, this entire thread is.
You guys are looking at this with Trump colored glasses and clinging to any ray of hope like oysters to a rock.
33   theoakman   2020 Mar 25, 8:39am  

While we haven't done the proper studies to verify whether or not it is effective...we know how anti-viral medications work and there's reasonable assumption that these medications would work simply because of the way they were designed to attack viral replication.

Not casting judgement on anyone here but its amazing that I'm reading people screaming about this because it's obvious they don't want any of these things to work. What you are viewing is the scientific process in action. We are actively collecting data and trying all kinds of therapies that should in theory aid and speed recovery. Several of them have a high probability of being somewhat effective. Official studies take much longer...but the initial data looks very promising. Anyone who is casting serious doubt on this is practicing science denial.
34   Tenpoundbass   2020 Mar 25, 9:22am  

Heraclitusstudent says
New study casts doubt on hyrdoxychloroquine’s effectiveness in treating coronavirus
https://techcrunch.com/2020/03/25/new-study-casts-doubt-on-hyrdoxychloroquines-effectiveness-in-treating-coronavirus/


Fuck the studies, the cases it's been used on is so far 100%, there is no will from the FDA to test it, they've had 15 fucking years to do clinical trials and testing.

Anyone believing any numbers from the FDA, CDC or the WHO is a fucking moronic idiot. They have less credibility than Geral Nadler explaining how Russia infiltrated Trump's 2016 campaign and stole the US phone number database, and robo called everyone to get everyone to vote for Donald Trump.
35   Tenpoundbass   2020 Mar 25, 9:25am  

I Blame the Democrats and the Commies, but I repeat myself for every death from this, since 3/20/2020.

The cure has been known, the Evil cocksuckers want it to go on, they think they are killing Trump voters, evil Fucks!
36   rocketjoe79   2020 Mar 25, 9:43am  

The two drugs in question have little or no side effects.
Two questions:

If your spouse had some symptoms of the virus, would you wait for a 5 day test turnaround time, or would you bully your doctor to give the drugs today?
Prince Charles has tested positive. What chance is there that he is NOT taking these antivirals?
37   Heraclitusstudent   2020 Mar 25, 10:42am  

It would be great if that works. There is a scientific process and you have to wait for the answer, and in the meantime acknowledge the signs that it is not working as much as the signs it is working.
38   Tenpoundbass   2020 Mar 25, 10:48am  

Heraclitusstudent says
There is a scientific process and you have to wait for the answer, and in the meantime acknowledge the signs that it is not working


That Process is corrupt, broken and doesn't give a fuck about what's best.

Sorry I would gnaw on a sassafras root per a Bohemian Shaman before I would trust what these self serving bastards think. Especially about vaccinations vs cures for diseases.
39   Tenpoundbass   2020 Mar 25, 10:53am  

Jonas Salk turned the Poli pandemic around in 3 years.

Polio Vaccine
In 1947, Salk took a position at University of Pittsburgh, where he began conducting research on polio, also known as infantile paralysis. By 1951, Salk had determined that there were three distinct types of polio viruses and was able to develop a "killed virus" vaccine for the disease. The vaccine used polio viruses that had been grown in a laboratory and then destroyed.

Fuaci has had 15 fucking years, since it was first reported these drugs are effective in treating Covid strains of viruses.

Get Real! There's an interest to explore this cure as an official FDA sanctioned treatment, like there's will from Rod Rosenstien to investigate Comey, Lynch and Clinton.

Stop it already with cheer leading ass kissing, it's indefensible the way the Establishment is carrying on. No excuse at all.

We don't get stats, updates, we don't get we contact and contagion zones, these mother fuckers aren't even interested in stopping the spread.
The only thing they report, is "OOH LOOK AT THE BIRDIE, 30 people died last night!"

That's a shitty way to do it if you ask me. So therefore they have my full vote of NO CONFIDENCE.
40   MisdemeanorRebel   2020 Mar 25, 12:05pm  

Demmedia: Trump wants to kill Grandpa!
Also Demmedia: Don't try promising treatment on very ill Grandpa, because (Trumpets, Clouds parting) the Holy Processes have not been followed!

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