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Japan drops vax rollout, goes to Ivermectin, ENDS COVID almost overnight
27 OCTOBER 2021
Robert W Malone, MD
@RWMaloneMD
21h
Ivermectin is effective for COVID-19.
Early treatment - 67% improvement, p < 0.0001
Late treatment - 36% improvement, p < 0.0001
126 global studies
UPDATE: 71 out of 75 Districts in Uttar Pradesh, India – Its Most Populated State – Reported No Covid-19 Cases in 24 Hours After Implementing Ivermectin Protocol
By Jim Hoft
Published October 30, 2021 at 11:43am
Robert W Malone, MD
@RWMaloneMD
22h
World’s Leading ICU Doctor Files Lawsuit Against Hospital System After Being Barred from Administering Safe and Effective COVID-19 Treatments
A Virginia Physician has been prohibited from using safe and time-honored medications in hospital while deaths from COVID-19 continue.
Another hospital hunting physicians who try to save their patients by administering lifesaving therapy. All we need is court allowance of legal discovery, and then this whole house of cards will fall.
America's Top Critical Care Doctor Sues to Save His Patients and the Hippocratic Oath (Paul Marik, Part I).
Dr. Marik helplessly watched seven covid patients die needlessly after his hospital denied his use of life-saving drugs. He goes to court Thursday for the right to use his judgement to save lives.
Michael Capuzzo
Dr. Pierre Kory: "Barring Dr. Marik from using the medicines he believes will help his patients is unconscionable, contrary to reason and science." (Marik, Part II)
Dr. Kory and Dr. Joseph Varon have saved thousands of covid patients who would have died elsewhere without the protocols Marik and these FLCCC physicians developed.
Joyce Kamen
A Virginia Doctor Calls for a Protest this Thursday Outside the Circuit Court in Norfolk to Support Dr. Paul Marik (Part III)
Dr Sheila Furey has saved many patients with Marik's protocols; "We need to send a message to the judge and to Sentara hospital that the doctor-patient relationship is sacred."
Sheila Furey, MD
In my neck of the woods, a doctor is suing a major hospital chain who is banning the Ivermectin the doctor wants to use to actually save lives:
https://www.wtkr.com/news/investigations/norfolk-doctor-files-lawsuit-against-sentara-on-ban-of-ivermectin-use-to-treat-covid-19
One of the few hundred "essential drugs" recommended for the most basic of health care clinics is now banned from a Hospital Chain.
The Media is Silent But the Data Speaks: How Ivermectin, Not Vaccines, Saved India's Largest State from Covid-19
Independent data scientist Chamie charts the results of some of the largest and most successful public health campaigns in history in Uttar Pradesh, population 241 million.
Parasitic worms are a significant confounder in some ivermectin studies,
Hospital Calls Police to Stop Texas Sheriff Deputy Getting Ivermectin: 'The Medicine Will Kill Him’
Exclusive first interview with Erin Jones who is trying to save her husband Jason Jones from dying of COVID
Emily Miller
Nov 12
On the latest episode of “The Jimmy Dore Show,” comedian and political commentator Jimmy Dore highlighted the similarities between Pfizer’s expensive new antiviral drug for COVID and ivermectin, a generic drug used to treat the virus.
“I’ve never seen the propaganda machine so hard at work as it’s been against ivermectin,” said Dore. “Ivermectin won a Nobel Prize for human medicine in 2015, but the media really has everyone believing it’s for horses.”
Dore suggested the motivation behind the propaganda is profits.
Dore played a video of John Campbell, Ph.D., explaining how Pfizer’s antiviral and ivermectin treat COVID in “the exact same way.” Campbell told viewers Pfizer’s new antiviral drug shows very high levels of efficacy in preventing severe disease, hospitalization and death.
BUY TODAY: Robert F. Kennedy, Jr.'s New Book — 'The Real Anthony Fauci'
“But there’s another drug, which is generic, called ivermectin, which works in the exact same way as the Pfizer antiviral,” Campbell said. “And there is conclusive proof from the scientific literature that the modality of action of the two drugs is the same. Both of these drugs inhibit viral replication.”
Campbell showed the molecular structure of Pfizer’s new drug and compared it to the molecular shape of ivermectin. He conceded the two “are completely different looking molecules” which led him to conclude “it’s absolutely fine to patent” the Pfizer drug.
“So they’re going to be able to make a lot of money out of it for the next 20 years,” he said.
Campbell cited a number of scientific papers which highlighted ivermectin’s effectiveness as an antiviral against COVID, including:
A paper from the Royal Society of Chemistry which concluded ivermectin exhibits “inhibition” to the “catalytic activity” which causes COVID to replicate.
An article in Nature which found that out of the 13 off-target drugs tested by researchers, only ivermectin blocked viral replication of SARS-CoV-2 by more than 80%.
A paper from The Royal Society of Chemistry which showed ivermectin, out of dozens of drugs the researchers experimented with, had the “highest score” when it comes to to stopping viral replication of SARS-CoV-2. Notably, the paper showed that Remdesivir, which is currently patented and approved by the U.S. Food and Drug Administration, had the lowest score out of all of the compounds.
Campbell also pointed to a paper from Frontiers in Microbiology, which he said showed ivermectin not only attacked and bound to COVID’s spike protein which stopped it from infecting the cell, but also bound to the cell receptor.
“So it doesn’t just work one way, but two different ways,” explained Dore. “It double screws it up so you can’t get COVID.”
Campbell put it this way: “Not only does ivermectin bend the COVID key, but it also ruins the lock.”
Campbell told viewers:
“So as far as we’ve been told, the new Pfizer drug is only working against one particular biochemical pathway to stop COVID, and with ivermectin, it’s working against that same biochemical pathway to stop COVID but also several others.”
“Why don’t you know this?” Dore asked. “Because ivermectin is cheap, and we live in a world that is made up of corporate propaganda.”
Watch the segment here: ...
A list of studies demonstrating the role of Ivermectin (IVM) on SARS-CoV-2
MAIN ROLE OF IVERMECTIN AGAINST SARS-COV-2 STUDY AUTHORS STUDY YEAR REFERENCES
A. DIRECT ACTION ON SARS-COV-2
Level 1: Action on SARS-CoV-2 cell entry
IVM docks in the region of leucine 91 of the spike protein and histidine 378 of the ACE2 receptor Leher et al. 2020 [22]
IVM has the highest binding affinity to the predicted active site of the S glycoprotein; Considerable binding affinity to the predicted active site of the SARS-CoV-2 RdRp protein; Highest binding affinity to the predicted active site of nsp14; highest binding affinity to the active site of the TMPRSS2 protein Eweas et al. 2021 [23]
IVM utilizes viral spike protein, main protease, replicase, and human TMPRSS2 receptors as the most possible targets for executing its antiviral efficiency by disrupting binding Choudhury et al. 2021 [24]
Level 2: Action on Importin (IMP) superfamily
in presence of a viral infection, IVM targets the IMPα component of the IMP α/β1 heterodimer and binds to it, preventing interaction with IMP β1, subsequently blocking the nuclear transport of viral proteins. Yang, S.N.Y et al. 2020 [26]
Level 3: Action as an Ionophore
Two ivermectin molecules, reacting with each other in a “head-tail” mode, can create a complex suitable to be considered as ionophore. These ionophores allow neutralizing the virus at an early stage of the infection before it can adhere to the host cells and enter it. Rizzo E et al. 2020 [28]
B. ACTION ON HOST TARGETS FOR VIRAL REPLICATION
Level 4: Action as an antiviral
IVM has antiviral properties against other viruses including the RNA viruses such as Zika Virus (ZKV), Dengue virus, yellow fever virus (YFV), and West Nile virus (WNV), Hendra virus (HEV), Newcastle virus, Venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV), Semliki Forest virus (SFV), and Sindbis virus (SINV), Avian influenza A virus, Porcine Reproductive and Respiratory Syndrome virus (PRRSV), Human immunodeficiency virus type 1 as well as DNA viruses such as Equine herpesvirus type 1 (EHV-1) and Pseudorabies virus (PRV). Heidary, F et al. 2020 [29]
Level 5: Action on viral replication and assembly
In Vero/hSLAM cells infected with the SARS-CoV-2 virus when “exposed” to 5 µM IVM showed a 5000-fold reduction in viral RNA at 48 h when compared to the control group Caly L et al. 2020 [30]
utilizing modeling approach, predicted lung accumulation of Ivermectin over 10 times higher than EC 50 Arshad et al 2020 [31]
best binding interaction between IVM and RNA-dependent RNA polymerase (RdRp) Swargiary et al.* 2020 [33]
highly efficient binding of IVM to nsp14 Ma et al. 2015 [35]
highly efficient binding of IVM to the viral N phosphoprotein and M protein Eweas et al. 2021 [23]
Level 6: Action on post-translational processing of viral polyproteins
IVM binds to both proteins, Mpro, and to a lesser extent to PLpro of SARS-CoV-2 Eweas et al. 2021 [23]
Level 7: Action on Karyopherin (KPNA/KPNB) receptors
IVM inhibits the KPNA/KPNB1- mediated nuclear import of viral proteins Caly L et al. 2020 [30]
C. ACTION ON HOST TARGETS FOR INFLAMMATION
Level 8: Action on Interferon (INF) levels
IVM promotes the expression of several IFN-related genes, such as IFIT1, IFIT2, IF144, ISG20, IRF9, and OASL Seth C 2016 [40]
Level 9: Action on Toll- like-Receptors (TLRs)
IVM blocks activation of NF-kappa B pathway and inhibition of toll-like receptor 4 (TLR4) signaling Zhang X et al. 2008 [42]
Level 10: Action on Nuclear Factor-κB (NF-κB) pathway
IVM at its very low dose, which did not induce cytotoxicity, drastically reversed the resistance of tumor cells to the chemotherapeutic drugs both in vitro and in vivo by inhibition of the transcriptional factor NF-κB. Jiang L et al. 2019 [44]
IVM inhibits lipopolysaccharide (LPS)-induced production of inflammatory cytokines by blocking the NF-κB pathway and improving LPS-induced survival in mice. Zhang X et al. 2008 [42]
Level 11: Action on the JAK-STAT pathway, PAI-1 and COVID-19 sequalae
IVM inhibits STAT-3, SARS-CoV-2-mediated inhibition of IFN and STAT 1, with the subsequent shift to a STAT 3- dominant signaling network that could result in almost all of the clinical features of COVID-19; STAT-3 acts as a “central hub” that mediates the detrimental COVID-19 cascade Matsuyama, T., 2020 [39]
STAT-3 induces a C-reactive protein that upregulates PAI-1 levels. Ivermectin inhibits STAT-3. Matsuyama, T., 2020 [39]
The PD-L1 receptors present on the endothelial cells are activated by STAT-3 causing T cell lymphopenia. IVM inhibits STAT-3 through direct inhibition Matsuyama, T., 2020 [39]
Level 12: Action on P21 activated Kinase 1 (PAK-1)
IVM suppresses the Akt/mTOR signaling and promotes ubiquitin-mediated degradation of PAK-1 hence compromising STAT-3 activity and decreasing IL-6 production. Dou Q et al. 2016 [54]
Level 13: Action on Interleukin-6 (IL-6) levels
IVM suppressed IL-6 and TNFα production Zhang X et al. 2008 [42]
IVM “dramatically reduced” IL-6/IL-10 ratio modulating infection outcomes. G D de Melo et al. 2020 [55]
Level 14: Action on allosteric modulation of P2X4 receptor
Positive allosteric modulation of P2X4 by IVM enhances ATP-mediated secretion of CXCL5 Layhadi JA et al. 2018 [58]
Level 15: Action on high mobility group box 1 (HMGB1)
Ivermectin inhibits HMGB1 Juarez M et al. 2018 [60]
Level 16: Action as an immunomodulator on Lung tissue and olfaction
No olfactory deficit was observed in IVM-treated females; IVM dramatically reduced the IL-6/IL-10 ratio in lung G D de Melo et al. 2020 [55]
Level 17: Action as an anti-inflammatory
anti-inflammatory action of IVM was explained as inhibition of cytokine production by lipopolysaccharide challenged macrophages, blockade of activation of NF-kB, and the stress-activated MAP kinases JNK and p38, and inhibition of TLR4 signaling.
Zhang X et al.,
Ci X et al.,
Yan S et al.
2008
2009
2011
[42, 62, 63]
Immune cell recruitment, cytokine production in bronchoalveolar lavage fluid, IgE, and IgG1 secretion in serum as well as hyper-secretion of mucus by goblet cells was reduced significantly by IVM Yan S et al. 2011 [63]
D. ACTION ON OTHER HOST TARGETS
Level 18: Action on Plasmin and Annexin A2
Annexin acts as a co-receptor for the conversion of plasminogen to plasmin in the presence of t-PA. increased levels of plasmin leads to direct activation of STAT-3. Kamber Zaidi et al. 2020 [64]
IVM directly inhibits STAT-3 and could play a role in the inhibition of COVID-19 complications. Matsuyama et al. 2020 [39]
Level 19: Action on CD147 on the RBC
The SARS-CoV-2 does not internalize into the red blood cells but such attachments can lead to clumping.
IVM binds to the S protein of the SARS-CoV-2 virus making it unavailable to bind with CD147.
David E.Scheim et al. 2020 [65]
Level 20: Action on mitochondrial ATP under hypoxia on cardiac function
IVM increased mitochondrial ATP production by inducing Cox6a2 expression and maintains mitochondrial ATP under hypoxic conditions. This prevents pathological hypertrophy and improves cardiac function. Nagai H et al.
Marik, who is the director of the Critical Care Unit at Sentara Norfolk General Hospital, is suing the healthcare system because they won't allow him to treat COVID-19 patients with the drug ivermectin, along with a host of other drugs that make up his developed MATH+ Protocol.
"Almost all of the treatments we use have been demonstrated to be safe and effective in randomized controlled trials," Marik said.
Marik claims that Sentara's policy may have led to the deaths of four of his patients who were never given the opportunity to learn of or be treated with potentially life-saving medicines. He said these actions are criminal.
"It's not just for me; it's for patients across the whole country. They have the right to choose what treatment they want," Marik said Thursday. "It's an outrage and yet there are other effective treatments available that they are trying to silence. The patients across this country need to know that they have options."
Marik's support of ivermectin was the subject of a different News 3 investigation in September.
A Judge Stands up to a Hospital: "Step Aside" and Give a Dying Man Ivermectin
A Chicago-area judge saved a grandfather's life with the single question that exposes hospitals blocking doctors from using a safe, FDA-approved drug: Why?
A pandemic of the vaccinated or Ivermectin ignored?
by Justus R. Hope, MD Nov 23, 2021 ...
Over the last 75 days, Delhi has recorded less than 10 COVID-19 deaths. Likewise, Uttar Pradesh, with more than 230 million people, has recorded fewer than 20 COVID deaths in the past 60 days, while the United States, with a roughly similar population, has recorded some 87,300 deaths - more than 4,000 times as many.
India's only remaining hotspot remains the highly vaccinated state of Kerala, which continues to pay the price. Over the last 30 days alone, Kerala has logged over 10,000 deaths. The main difference between Kerala and the rest of India was its lower use of Ivermectin, as I wrote on August 23, 2021, in an article published in the Desert Review.
https://www.thedesertreview.com/opinion/columnists/indias-ivermectin-blackout---part-iii-the-lesson-of-kerala/article_ccecb97e-044e-11ec-9112-2b31ae87887a.html
Out of India's 267 deaths reported on November 19, 2021, fully 204 came from Kerala. With 36 million people, tiny Kerala represents only 2.5% of India's population of 1.399 billion. However, they have 76% of India’s daily COVID-19 deaths. In other words, it is 30 times more likely for an Indian resident of Kerala to die from the virus compared to a resident outside the state.
But look at other cases. For example, Indonesia adopted Ivermectin and saw their COVID-19 cases drop from 45,000 in July to 347 cases per day in November of 2021 - a drop of 99.2%.
Meanwhile, Gibraltar's cases doubled during the same time frame from an average of 30 per day to 60 per day. The United States' daily cases doubled between July 22 and November 19.
Singapore, a nation that enjoys a fully vaccinated percentage of 88.2% as of November 5, 2021, also sees COVID-19 cases moving fast in the wrong direction. Between July 23 and November 20, 2021, Singapore saw their cases rise from 130 to 1931 per day - an increase of 15 fold.
I need to add that we also doubled up on Vit C, Vit D, K2, Quercetin and Allisure Allicin.
WineHorror1 saysI need to add that we also doubled up on Vit C, Vit D, K2, Quercetin and Allisure Allicin.
Realize, R-Lipoic Acid recycles the Vitamin C and E in one's body. Thus, make sure you have it in your diet.
LIttle oopssie from the past:
Rin saysWineHorror1 saysI need to add that we also doubled up on Vit C, Vit D, K2, Quercetin and Allisure Allicin.
Realize, R-Lipoic Acid recycles the Vitamin C and E in one's body. Thus, make sure you have it in your diet.
@Rin, I don't have any R-Lipoic Acid. Can you help me find it?
Robert W Malone, MD
@RWMaloneMD
1h
The thing is, who determines what is an effective "protocol"? At the moment, it is CDC and NIH/Fauci (which are not actively engaged in practicing medicine and treating patients) in collusion with Large Pharma. Which is why we are seeing so, so many excess unnecessary deaths.
4:35 PM · Nov 25, 2021
From Near Death in a Hospital to Happy at Home, a Father Is Saved by His Daughter and Ivermectin
Sun Ng's daughter had to sue an Illinois hospital to allow a doctor to give her father the safe, FDA-approved drug that saved his life.
Trista Ng asked officials at Edward Hospital again and again. Give my father ivermectin for covid.
“Numerous times” the Naperville, Illinois, hospital told her no, she said. No to an FDA-approved drug. No to her offer to release the hospital of “any liability.”
“The doctors and administration refused,” she wrote in a plea to DuPage County Circuit Court Judge Paul Fullerton, who on November 5 answered with a simple yes, telling hospital administrators, “Step aside.”
Last Saturday, nineteen days after his first of five court-ordered ivermectin doses, Sun Ng, seventy-one, came home: To a joyful wife of forty years, Ying. To a year-old granddaughter, Kaylie. To a son-in-law, Hayden, and a daughter who asked only—after the hospital’s menu of Covid care had failed—to give her father “a fighting chance.”
https://nitter.pussthecat.org/RWMaloneMD/status/1463909133250437127#m
Robert W Malone, MD
@RWMaloneMD
1h
The thing is, who determines what is an effective "protocol"? At the moment, it is CDC and NIH/Fauci (which are not actively engaged in practicing medicine and treating patients) in collusion with Large Pharma. Which is why we are seeing so, so many excess unnecessary deaths.
4:35 PM · Nov 25, 2021
From the Spring of 2020 forward, very few people on earth were true victims of the covid-19 virus.
Allow me to explain.
Since then, the sick, the dying—indeed all of us—became victims of a far more blackhearted foe than the virus itself: unchecked greed—which has triumphed in its mission to prevent the world from ending this pandemic—when we knew full well how to do it over eighteen months ago.
In other words, this all could have been over by January or February of 2021.
All of it.
The case counts.
The hospitalizations.
The suffering.
The comas.
The despair.
The deaths.
The grieving.
The funerals.
All of it.
Instead, beginning in late Spring, 2020, as some of the world’s most gifted, published, and renowned medical minds in the field of critical care were quite literally imploring public health agencies across the globe to listen to the scientific evidence that pointed to a rapid and safe way out of the pandemic using repurposed, FDA-approved drugs, they were censored and silenced. In well-orchestrated, meticulously coordinated media campaigns, they and the organizations they represented were slandered as “fringe,” “crackpots,” “snake-oil salesmen,” and worse. Soon, physicians and many other allied health professionals began to lose their livelihoods. Their reputations suffered. Some lost their licenses to practice medicine, others were levied fines for daring to speak publicly of the science they knew would save their patients’ lives.
A few were arrested and are facing trial and potential prison time. ...
Yet, their greedy eyes turned only one way: To the blinding glow of global profit-making from vaccines meant to stop the spread of COVID-19. This was a payday that could stretch for decades—an opportunity for treasure beyond measure—unlike any other ever known. They were determined that nothing—even the loss of hundreds of thousands of lives—would get in their way.
Kennedy writes in his book:
“The following week, she spoke to Hill again, this time by Zoom. The Zoom call was recorded.
“Dr Lawrie asked Hill to explain his U-turn on ivermectin, which his own analysis found overwhelmingly effective. ‘How can you do this?’ she inquired politely. ‘You are causing irreparable harm.’ Hill explained that he was in a ‘tricky situation’ because his sponsors had put pressure on him. Hill is a University of Liverpool virologist who serves as an adviser to Bill Gates and the Clinton Foundation. He told me his sponsor was Unitaid.
“Unitaid is a quasi-governmental advocacy organization funded by the Bill & Melinda Gates Foundation (BMGF) and several countries — France, the United Kingdom, Norway, Brazil, Spain, the Republic of Korea and Chile — to lobby governments to finance the purchase of medicines from pharmaceutical multinationals for distribution to the African poor.
“Its primary purpose seems to be protecting the patent and intellectual property rights of pharmaceutical companies — which, as we shall see, is the priority passion for Bill Gates — and to ensure their prompt and full payment. About 63 percent of its funding comes from a surtax on airline tickets.
“The BMGF holds a board seat and chairs Unitaid’s Executive Committee, and the BMGF has given Unitaid $150 million since 2005. Various Gates-funded surrogate and front organizations also contribute, as does the pharmaceutical industry.
“The BMGF and Gates personally own large stakes in many of the pharmaceutical companies that profit from this boondoggle. Gates also uses Unitaid to fund corrupt science by tame and compromised researchers like Hill that legitimizes his policy directives to the WHO.
“Unitaid gave $40 million to Andrew Hill’s employer, the University of Liverpool, four days before the publication of Hill’s study. Hill, a Ph.D., confessed that the sponsors were pressuring him to influence his conclusion. When Dr. Lawrie asked who was trying to influence him, Hill said, ‘I mean, I, I think I’m in a very sensitive position here …’”
With Ivermectin in Hand, Wife Dies While Husband Begs Hospital to Administer
BY BETH BRELJE December 11, 2021 Updated: December 11, 2021biggersmaller Print
David DeLuca of Sicklerville, New Jersey will never know if the Ivermectin prescribed by an out-of-state doctor for his wife would have saved her life. Colleen DeLuca, 62, died of COVID-19 on Oct. 10, at Jefferson Washington Township Hospital in Sewell, New Jersey, before he could get a court order to administer the drug.
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And HCQ falls into that same bucket. Even worse - to admit HCQ works would be to admit Trump was right about something.
Liberals would rather that millions die than that Trump be allowed to be right about anything. They hate Trump more than they love their fellow humans.