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Early vaccinees are twice as likely to catch COVID as later recipients

By Al_Sharpton_for_President follow Al_Sharpton_for_President   2021 Jul 26, 8:22am 221 views   10 comments   watch   nsfw   quote   share    


Latest research ‘definitely’ reinforces argument for giving boosters to the elderly, says lab chief at Leumit.

People vaccinated before late February are twice as likely to catch the coronavirus than other inoculated Israelis, according to new research.

“We looked at tens of thousands of people tested in the month of June, alongside data on how long had passed since their second shot, and found that those vaccinated early were more likely to test positive,” Dr. Yotam Shenhar, who headed the research, told The Times of Israel.

“This definitely reinforces the argument for giving a third vaccine dose to the elderly.”

The report, published by the healthcare provider Leumit, comes on the heels of other Israeli studies that suggest a decreasing vaccine effectiveness, partly as a result of the Delta variant and partly because of the passage of time. However, British data indicates the Israeli studies may be overstating the case.

Data released by the Health Ministry on Thursday suggested that people vaccinated in January were said to have just 16% protection against infection now, while in those vaccinated in April the effectiveness was at 75%

The Leumit study looked only at the apparent waning of protection over time, and divided the vaccinated population into two based on inoculation dates, comparing early vaccinators to late vaccinators.

Shenhar, head of Leumit’s labs, acknowledged that the early vaccinators group includes many people who raced to get shots because they have underlying illnesses, which may make them more vulnerable to infection. But he said that could not fully account for the stark effect seen in the data.

Shenhar said the data should prompt the government to seriously consider booster shots for over-70s.

“Now we see vaccination effectiveness drops, so it seems we definitely need to think about a third vaccine,” he said. “We have started already by giving the immunocompromised, but in my assessment we need to consider giving third shots to everyone over 70 or 80. We shouldn’t wait long; we need to make a decision fast.”

If he were formulating policy, Shenhar said, he would “definitely” start giving boosters to elderly Israelis.

In his study, the apparent waning effect in immunity was felt across all ages. For all age groups, early vaccinators were 1.95 times more likely to be confirmed coronavirus positive. Among those aged 60-plus, early vaccinators are twice as likely to get infected. For those aged 40-59 early vaccinators are 2.1 times more vulnerable, and among under 39s they are 1.6 more likely to catch the coronavirus.

“In a previous analysis we showed that as time passes since the vaccine, the level of antibodies drops at a rate of about 40% per month. This new study builds a clearer picture of the effect seen in the months after vaccination,” said Shenhar.

Israel has seen a dramatic rise in recent COVID-19 infections, with the daily caseload rising from several dozen to over 1,400 in recent days.

https://www.timesofisrael.com/hmo-those-who-inoculated-early-twice-as-likely-to-catch-covid-as-later-adopters/

1   Onvacation   ignore (7)   2021 Jul 26, 9:05am     ↓ dislike (0)   quote   flag      

The passport will require biannual jabs, if you want to eat.
2   FuckCCP89   ignore (6)   2021 Jul 26, 10:27am     ↓ dislike (0)   quote   flag      

Onvacation says
The passport will require biannual jabs, if you want to eat.


Will every Safeway truck be escorted by a platoon of Marines?
3   NuttBoxer   ignore (2)   2021 Jul 26, 11:12am     ↓ dislike (0)   quote   flag      

So if something doesn't work, do it more? Getting awfully close to the definition of insanity...
4   WookieMan   ignore (6)   2021 Jul 26, 11:14am     ↓ dislike (0)   quote   flag      

NuttBoxer says
So if something doesn't work, do it more? Getting awfully close to the definition of insanity...

I think we're there Nutt unfortunately.
5   Onvacation   ignore (7)   2021 Jul 26, 1:25pm     ↓ dislike (0)   quote   flag      

FuckCCP89 says
Onvacation says
The passport will require biannual jabs, if you want to eat.


Will every Safeway truck be escorted by a platoon of Marines?

Yup.
6   richwicks   ignore (3)   2021 Jul 26, 3:41pm     ↓ dislike (0)   quote   flag      

Al_Sharpton_for_President says
Early vaccinees are twice as likely to catch COVID as later recipients


I'm curious how likely later recipients are to get "covid" versus the unvaccinated..
7   HeadSet   ignore (3)   2021 Jul 27, 8:35am     ↓ dislike (0)   quote   flag      

Odd that the article does not mention which vaccine. The Pfizer, AstraZeneca, and J&J cannot be exactly the same in terms of effectiveness or susceptibility to causing reduced immunity.
8   NuttBoxer   ignore (2)   2021 Jul 27, 9:01am     ↓ dislike (0)   quote   flag      

HeadSet says
Odd that the article does not mention which vaccine. The Pfizer, AstraZeneca, and J&J cannot be exactly the same in terms of effectiveness or susceptibility to causing reduced immunity.


Actually...
"ARRs tend to be ignored because they give a much less impressive effect size than RRRs: 1·3% for the AstraZeneca–Oxford, 1·2% for the Moderna–NIH, 1·2% for the J&J, 0·93% for the Gamaleya, and 0·84% for the Pfizer–BioNTech vaccines."

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(21)00069-0/fulltext
9   Onvacation   ignore (7)   2021 Jul 27, 10:17pm     ↓ dislike (0)   quote   flag      

FuckCCP89 says
Onvacation says
The passport will require biannual jabs, if you want to eat.


Will every Safeway truck be escorted by a platoon of Marines?

yup
10   Karloff   ignore (0)   2021 Jul 27, 10:35pm     ↓ dislike (0)   quote   flag      

https://conservativeplaylist.com/2021/07/27/delta-variant-natural-immunity-700-better-than-the-vaccine/

"Natural COVID Immunity May Last a Lifetime

It was initially suggested that natural COVID-19 immunity may be short-lived. This was based on early data on SARS-CoV-2, which found that antibody titers declined rapidly in the first months after recovery from COVID-19. According to a team of researchers from the Washington University School of Medicine, however, if you’ve had COVID-19 — even a mild case — you’re likely to be immune for life, as is the case with recovery from many infectious agents.17

According to senior author of the study Ali Ellebedy, Ph.D., an associate professor of pathology and immunology at Washington University School of Medicine in St. Louis, “It’s normal for antibody levels to go down after acute infection, but they don’t go down to zero; they plateau.”18

The researchers found a biphasic pattern of antibody concentrations against SARS-CoV-2, in which high antibody concentrations were found in the acute immune response that occurred at the time of initial infection. The antibodies declined in the first months after infection, as should be expected, then leveled off to about 10% to 20% of the maximum concentration detected.

When a new infection occurs, cells called plasmablasts provide antibodies, but when the virus is cleared, longer lasting memory B cells move in to monitor blood for signs of reinfection.19 Bone marrow plasma cells (BMPCs) also exist in bones, acting as “persistent and essential sources of protective antibodies.”20 Ellebedy even said the protection provided by naturally acquired immunity is likely to continue “indefinitely”:21"

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