T-cell tests such as T-detect for SARS-Cov2

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T-cell tests such as T-detect for SARS-Cov2

invite response
2021 Oct 29, 10:29am 736 views 7 comments

I tried to find a thread about personal experiences people might have had with the T-Detect brand T-cell tests. But I can't find much so far. That seemed odd to me. Can anyone provide a link to such a thread? I'm especially interested in what a T-detect "certificate" or test results look like. If anyone has a copy of test result that they can suitably redact and post that would be great.

Additionally, a main point of interest is how long was the time between your (suspected) infection, and a positive (or negative) T-detect test. There has been no proper trial beyond 10 months, so anecdotal evidence of positive/negative tests with a larger than 10-month spacing is especially interesting.

The above are my main questions.

Side topic, please do not get too hung up on this: More generally, on the topic of searching for material on patrick.net: It looks to me like Google no longer indexes patrick.net. Is that a choice made by Patrick himself or is it a choice by google? I did not have much luck with Bing either. As for duckduckgo, I could not find a way to restrict a search to a specific site. Any workarounds?

Comments 1 - 7 of 7 Search these comments

Tenpoundbass 2021 Oct 29, 10:36am

You just proved Duck Duck Go is sipping water from Googles fetid mud hole.

Al_Sharpton_for_President 2021 Oct 29, 10:50am

Go to the For Physicians section, click Learn More, and read the provided references. You can Google the titles, or go to Pubmed to search them.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010755/

https://www.medrxiv.org/content/10.1101/2021.01.06.21249345v1

it is from Adaptive Bio, a company which did something very obvious once high-throughput sequencing became commercially feasible, and commercialized T cell receptor (TCR) sequencing. The icing on the cake would be a functional assay, demonstrating T cell activation upon exposure to viral antigen, or lysis of a virally infected cell line.

Peptide-MHC and the TCR - one of the collosal breakthroughs in the understanding of how the immune system worked circa mid '80's-early '90's.

justme 2021 Oct 29, 10:57am

Thanks, Al_Sharpton. The above is a great resource for people who have not heard about or yet read up on T-cell testing in general, and T-detect for SC2 in particular.

However, I am fully read up about everything T-detect, and I am still looking to hear about personal experiences, and suitably redacted views of certificates!!

By the way, the current price for T-detect is $219 (150+9+60 = test + doctors order + blood draw), for those wondering.

Patrick 2021 Oct 29, 9:47pm

@justme Try a search like this on yandex.com:

site:patrick.net virus

Should work.

Al_Sharpton_for_President 2021 Oct 30, 3:23am

justme says

I am still looking to hear about personal experiences

Are you attempting to determine if employers will accept a confirmatory report as proof of natural vaccination and immunity to the virus? A science based argument can certainly be made, but who will make it?

There are quite a few logic holes in the official position on vaccination as it is.

1. As the infected vaccinated can carry an equivalent viral load to the unvaccinated infected and can transmit the virus, mere proof of vaccination does not equate to prevention of viral transmission.
2. Spike protein antibody titers wane over time which mere proof of vaccination does not measure.
3. Should the limited breadth vaccine induced immune response to the spike protein be viewed as inferior to a broader immune response to the spike protein, the nucleocapsid protein, and other viral antigens, as can be determined by TCR sequencing, or even lateral flow immunoassay?

justme 2021 Oct 30, 8:49am

Al_Sharpton_for_President says

Are you attempting to determine if employers will accept a confirmatory report as proof

I have updated my original post to be more specific. I'll enumerate what I am trying to determine

1. A survey of persons that took the T-detect test >10 months after suspected infection, and what result they got. Anecdotal evidence needed. Not much on web.

2. Does the test result document have the necessary characteristics to serve as an "immunity passport", by being similar to a "vaccine passport". That is, does it have (a) a secure server (YES) (b) a digital signature (unknown) via (c) a QR code stamped on the test result (unknown)

Any and all answers to the SPECIFIC questions above is what I am looking for. The general idea is "should I bother" and "does the test report even have a snowballs chance in hell of being useful for any official purpose".

Al_Sharpton_for_President 2021 Oct 30, 11:50am

justme says

A survey of persons that took the T-detect test >10 months after suspected infection, and what result they got.

if you contact the academic investigators cited in the above publications, they may offer some information, or at least best guesses under qualified assumptions. The company scientists, maybe not. But the company wll probably be able to provide information on the report, server, QR code and their experience of acceptance as a passport.

patrick.net

T-cell tests such as T-detect for SARS-Cov2

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