patrick.net

Onvacation says

Almost half west Asian...

The lizard DNA won't bind to the beads in the Illumina bead chip microarray. (I used to help design them; 23andme buys them from ILMN) The swab was contaminated with human DNA. (sorry for the spoiler)

@just_passing_through

My wife does not match a known 3rd cousin at all on 23andme. Yet the 3rd cousin and my wife both match with a 2nd cousin of my wife.

I think this is actually possible, because maybe the 3rd cousin just didn't happen to inherit enough overlap with my wife to be detectable.

Arrays are cheap and old technology. It's like taking a sample of a word from every page in a decent sized phone book. But super duper cheap. If you really want to do genetic analysis these days you'd use NGS (Next Generation Sequencing) capable of reading every word in the phone book. The step after that would be variant calling (typically) where your phone book is compared to a reference phone book and differences are noted. (outputs a VCF file if you care to dig into that)

The reason the lizard DNA isn't legit is the chip is covered in short sequences of human dna. Only complementary DNA (other strand of human DNA) would bind to it. Now if it were the case that 'some' of the lizard DNA just happened to bind it wouldn't be much and would fail QC. You'd at least need most of the beads hybridized with DNA to pass QC, thus, it's human DNA. Or the whole thing might just be BS.

There are dropouts in microarrays so that would explain your situation. A certain amount is tolerated. Same with NGS sequencing but it's called missing coverage - you just don't get a read over certain areas.. However good sequencing panel designs are aware of difficult regions and enrich for them.

Someday these ancestry companies will switch to sequencing but it's still ~$500-1K per genome. Most people wouldn't pay for that.

Patrick says

low concrete wall hidden behind the wooden fence.

just_passing_through says

Now if it were the case that 'some' of the lizard DNA just happened to bind it wouldn't be much and would fail QC. You'd at least need most of the beads hybridized with DNA to pass QC, thus, it's human DNA. Or the whole thing might just be BS.

There you go. Spoiling the Khazarian Mafia Iguana conspiracy theory. You owe us a new conspiracy theory for that.

At my kitchen sink I saw a small spider wrapping up a much larger wasp. How does that happen? The wasp has a fucking stinger.

Anyway, I caught them both in a cup and liberated them outdoors. The wasp flew away. The spider cursed me, no doubt.

Patrick says

I caught them both in a cup and liberated them outdoors.

From our farm, caught this one in a kitchen sink:

Patrick says

At my kitchen sink I saw a small spider wrapping up a much larger wasp. How does that happen? The wasp has a fucking stinger.

I don't bother spiders that are 'good' spiders aka Daddy Long Legs, who will set up nests to catch and kill 'bad spiders' like the crawly bitey ones (various recluse type spiders). Daddy Long Legs have badass venom, but they can't bite people. In spite of being small, they can kill and consume surprisingly large prey. I have quite a cluster of them in my lion's den bathroom, and I just clean their webs out after they seem to leave for the season.

I also watch them and their habits, it's kind of fascinating.

Ceffer says

I don't bother spiders that are 'good' spiders aka Daddy Long Legs,

If you have spiders you have spider food. I prefer to let the spiders win.

I was cleaning out the woodshed a couple of weeks ago and a large black widow crawled out from under a shelf from across the room. I wasn't afraid of her, but I got the message.

I would have gassed it and flipped him right out of the car.

RC2006 says

I would have gassed it and flipped him right out of the car.

It could only happen if you're one of those pricks that blocks the intersection walkway.

richwicks says

This is basically an anonymous person that had an affair with a patient, who unfortunately died.

THAT'S how I want to go when I get old.

Ceffer says

Except the hand is obviously female. Has Ceffer finally fallen victim to the gender confusion?

"I can't wait for the girl to hit 40 and become desperate for a man's company."

clambo says

"I can't wait for the girl to hit 40 and become desperate for a man's company."

Most women are ugly as fuck by 40.