patrick.net

https://www.sciencedirect.com/science/article/pii/S0924857920300662

The novel coronavirus currently isolated in China has been, with staggering speed, evaluated regarding its sensitivity to already used drugs [12]. Thus, the new antiviral drug remdesivir [13] as well as chloroquine, at an EC50 of 1.1 µM, were found to be effective in preventing replication of this virus [12]. Chloroquine is perhaps one of the most prescribed drugs in the world [14,15]. As a matter of fact, all Europeans visiting malaria-endemic geographic areas for decades received chloroquine prophylaxis and continued it for 2 months after their return. In addition, local residents took chloroquine continuously, and treatment of malaria has long been based on this drug. In addition, hydroxychloroquine has been used for decades at much higher doses (up to 600 mg/day) to treat autoimmune diseases [16]. It is difficult to find a product that currently has a better established safety profile than chloroquine. Furthermore, its cost is negligible.

The Chinese say so too:

http://english.www.gov.cn/statecouncil/ministries/202002/17/content_WS5e4a944dc6d0595e03c20f35.html

BEIJING — Chinese experts, based on the result of clinical trials, have confirmed that Chloroquine Phosphate, an antimalarial drug, has a certain curative effect on the novel coronavirus disease (COVID-19), a Chinese official said here on Feb 17.

The experts have "unanimously" suggested the drug be included in the next version of the treatment guidelines and applied in wider clinical trials as soon as possible, Sun Yanrong, deputy head of the China National Center for Biotechnology Development under the Ministry of Science and Technology, said at a press conference.

Chloroquine Phosphate, which has been used for more than 70 years, was selected from tens of thousands of existing drugs after multiple rounds of screening, Sun said.

According to her, the drug has been under clinical trials in over 10 hospitals in Beijing, as well as in South China's Guangdong province and Central China's Hunan province, and has shown fairly good efficacy.

In the trials, the groups of patients that have taken the drug have shown better indicators than their parallel groups, in abatement of fever, improvement of CT images of lungs, the percentage of patients who became negative in viral nucleic acid tests and the time they need to do so, she said.

Patients taking the drug also take shorter time to recover, she added.

Sun gave an example of a 54-year-old patient in Beijing, who was admitted to hospital four days after showing symptoms. After taking the drug for a week, he saw all indicators improve and the nucleic acid turn negative.

So far, no obvious serious adverse reactions related to the drug have been found among the over 100 patients enrolled in the clinical trials, she said.

WookieMan says

I wonder if the couples cam porn industry is going to boom now?

We're finally gonna get a baby boom out of these millennials!

Tarzana Medical Center right now is full with Corona patients, one is a doctor. Those numbers are not yet reported. But they went up a lot lately.

I started listening to the local 10PM news broadcast on the TV the past 2 days. I haven't done that in a few years.

A Coronavirus Explosion Was Expected in Japan. Where Is It?

Japan was one of first countries outside of China hit by the coronavirus and now it’s one of the least-affected among developed nations. That’s puzzling health experts.
Unlike China’s draconian isolation measures, the mass quarantine in much of Europe and big U.S. cities ordering people to shelter in place, Japan has imposed no lockdown. While there have been disruptions caused by school closures, life continues as normal for much of the population. Tokyo rush hour trains are still packed and restaurants remain open.
The looming question is whether Japan has dodged a bullet or is about to be hit.

....

“Italy’s mortality rate is almost triple Japan’s,” said Yoko Tsukamoto, a professor of infection control at the Health Sciences University of Hokkaido. “Part of the reason is if you get tested, you get quarantined, so it means that they don’t have enough beds for relatively non-severe patients.”
Japan has tested more than 15,000 people as of Wednesday, and despite discouraging checks on those who don’t have symptoms or contact with a carrier, the infection rate lies at 5.6%. That compares to around 3% in South Korea, but 18% in Italy.
“We don’t see a need to use all of our testing capacity, just because we have it,” Health Ministry official Yasuyuki Sahara said at a briefing Tuesday. “Neither do we think it’s necessary to test people just because they’re worried.”

....


https://apple.news/AGmpWO7u_TGK0WtLBco5A7g

https://www.nature.com/articles/d41586-020-00758-2

How does COVID-19 compare to other diseases?
Current estimates of COVID-19’s case fatality rate — a measure of the proportion of infected people who eventually die — suggest that the coronavirus is less deadly than the pathogens behind other large-scale outbreaks, such as of SARS (severe acute respiratory syndrome), MERS (Middle East respiratory syndrome) and Ebola.

But the infection also seems to spread more easily than other diseases, including seasonal influenza. Calculations of the virus’s basic reproduction number, or R0 — the number of people on average one infected person will pass the virus to — suggest a range of 2–2.5.

https://www.cdc.gov/flu/pandemic-resources/1957-1958-pandemic.html

TEOTWAWKI says

A Coronavirus Explosion Was Expected in Japan. Where Is It?

Japan was one of first countries outside of China hit by the coronavirus and now it’s one of the least-affected among developed nations. That’s puzzling health experts.
Unlike China’s draconian isolation measures, the mass quarantine in much of Europe and big U.S. cities ordering people to shelter in place, Japan has imposed no lockdown. While there have been disruptions caused by school closures, life continues as normal for much of the population. Tokyo rush hour trains are still packed and restaurants remain open.
The looming question is whether Japan has dodged a bullet or is about to be hit.

....

“Italy’s mortality rate is almost triple Japan’s,” said Yoko Tsukamoto, a professor of infection control at the Health Sciences University of Hokkaido. “Part of the reason is if you get tested, you get quarantined, so it means that they don’t have enough beds for relatively non-severe patients....

Well you know why. The Japanese are polite and clean. Basic hygiene and manners go a long way.

https://www.usatoday.com/story/news/nation/2020/03/19/flushed-t-shirts-clog-california-citys-sewer-amid-toilet-paper-panic/2880815001/

The irony!


Carnival offers cruise ships to relieve strain on hospitals

https://www.straitstimes.com/world/united-states/coronavirus-carnival-offers-cruise-ships-to-relieve-strain-on-hospitals

Graphs from French study:



Looks like chloroquine is more effective when combined with azithromycin.

from https://www.en24.news/a/2020/03/hydroxychloroquine-would-be-effective-according-to-professor-raoult-of-the-ihu-in-marseille-after-a-first-limited-test.html

Strangely, the general health of the public gets better during depressions:

Recent events highlight the importance of examining the impact of economic downturns on population health. The Great Depression of the 1930s was the most important economic downturn in the U.S. in the twentieth century. We used historical life expectancy and mortality data to examine associations of economic growth with population health for the period 1920–1940. We conducted descriptive analyses of trends and examined associations between annual changes in health indicators and annual changes in economic activity using correlations and regression models. Population health did not decline and indeed generally improved during the 4 years of the Great Depression, 1930–1933, with mortality decreasing for almost all ages, and life expectancy increasing by several years in males, females, whites, and nonwhites. For most age groups, mortality tended to peak during years of strong economic expansion (such as 1923, 1926, 1929, and 1936–1937). In contrast, the recessions of 1921, 1930–1933, and 1938 coincided with declines in mortality and gains in life expectancy. The only exception was suicide mortality which increased during the Great Depression, but accounted for less than 2% of deaths. Correlation and regression analyses confirmed a significant negative effect of economic expansions on health gains. The evolution of population health during the years 1920–1940 confirms the counterintuitive hypothesis that, as in other historical periods and market economies, population health tends to evolve better during recessions than in expansions.

https://www.pnas.org/content/106/41/17290

Huh, Wuhan virus disproportionately affects areas that vote for globalist Democrats. Karma at work?

To be certain, COVID-19 is hammering the entire U.S., regardless of geographic location or political affiliation. And the coming economic calamity is expected to leave no industry or region unscathed.

Yet as the virus brings activity on both coasts — which overwhelmingly voted for Hillary Clinton in 2016 — to a grinding halt, the demographics underscore how Democratic areas are being more heavily impacted than Republican ones. ...

According to the CDC, there are over 4,600 confirmed cases in New York State, and in New York City, there are nearly 4,000 infections and rising. That was double the figures that had been released just the day prior.

Meanwhile the partisan skew is obvious: The unabashedly liberal Big Apple hasn’t voted for a Republican president since 1924; and in 2016, Clinton won roughly 87% of Manhattan’s vote against fellow New York resident Donald Trump.

https://finance.yahoo.com/news/coronavirus-hitting-democrat-communities-more-than-republican-ones-143813828.html

Patrick says

Wuhan virus disproportionately affects areas that vote for globalist Democrats

Yes, I noticed that, while the disgusting flyover country is relatively mild.

https://www.livescience.com/coronavirus-updates-united-states.html

Also, this mass self-quarantine may wipe out certain strains of cold, flu, and other diseases because the chains of transmission are being broken.

Hell, venereal diseases will probably also decrease for the same reason.

And even though the economy is getting whacked, many countries have lived through economic devastation before and then rebounded. Could take years, but things will recover.

Lol, the rich are getting access to Wuhan virus tests ahead of everyone else:

https://www.cnbc.com/2020/03/20/how-one-elite-new-york-medical-provider-got-its-patients-coronavirus-tests.html

Not surprising.

More about the French experience with chloroquine:

This week, French researchers released results from a preliminary trial using 36 COVID-19 patients. The study, headed by Didier Raoult from Aix-Marseille University in France, has not yet been peer-reviewed but shows promising results.Twenty of the patients received 600 milligrams of hydroxychloroquine daily, and the remainder did not to act as a control group.After six days, 70% of the patients who received the drug were considered cured, compared with only 12.5% of the control group, according to Newsweek.

Patrick says

Huh, Wuhan virus disproportionately affects areas that vote for globalist Democrats. Karma at work?

Not karma: just density, public transportation, uncontrolled immigration, outsized homeless population, etc.

Patrick says

Lol, the rich are getting access to Wuhan virus tests ahead of everyone else

Test-shmest. I fail to see a point for an individual to test for that shit: if your symptoms are mild just ride it out, if they are severe - get hospitalized.

Tax day now put off. Even the filing date now (filing date is the latest part):

https://finance.yahoo.com/news/irs-extends-tax-deadline-to-july-15-from-april-15-143136026.html
Treasury Secretary Steven Mnuchin announced that tax day will be delayed from April 15 to July 15. He made the announcement on Twitter on Friday, days after announcing a deferral on tax payments but not on filing day.

“All taxpayers and businesses will have this additional time to file and make payments without interest or penalties,” Mnuchin tweeted.

At @realDonaldTrump’s direction, we are moving Tax Day from April 15 to July 15. All taxpayers and businesses will have this additional time to file and make payments without interest or penalties.

Time to postpone the property tax too.

TEOTWAWKI says

Not karma: just density, public transportation, uncontrolled immigration, outsized homeless population, etc.

Those second two definitely are the results of Democratic policies. So it could definitely be karma.

China had 3200 deaths out of 81000 cases in a country with 1.4b people which is .04% death rate. Korea has 51b people had 8600 cases with 94 deaths which is .01%. Granted S Korea does more testing but given that line of thinking and getting the results of doing more testing, it seems to me this lends to a DECREASE in the mortality rate. Italy- not sure what's going on there other than they have a LOT of elderly, people kiss each other upon greeting, they live in close proximity to one another and spend a lot of time outdoors together. Even with all that said, so far their rate is still only .08%.

zzyzzx says

China had 3200 deaths out of 81000 cases in a country with 1.4b people which is .04% death rate. Korea has 51b people had 8600 cases with 94 deaths which is .01%. Granted S Korea does more testing but given that line of thinking and getting the results of doing more testing, it seems to me this lends to a DECREASE in the mortality rate. Italy- not sure what's going on there other than they have a LOT of elderly, people kiss each other upon greeting, they live in close proximity to one another and spend a lot of time outdoors together. Even with all that said, so far their rate is still only .08%.

Exactly. And all those deaths concentrated in the old and infirm to boot.

Deaths always go down during an epidemic while cases rise because A) It begins to move into the young and healthy who are highly likely to survive it and B) Increased Treatment Experience.

Last time I went to WalMart, only saw 3 people wearing masks. All of them black.

https://www.powerlineblog.com/archives/2020/03/stop-the-insane-overreaction.php

zzyzzx says

Last time I went to WalMart, only saw 3 people wearing masks. All of them black.

Last time I went to my cheapass Paki store, I saw only 10 womyn wearing masks, but they were wearing masks long before corona outbreak:

zzyzzx says

Pam! Pam! Pam!

Ceffer says

rd6B says

Last time I went to WalMart, only saw 3 people wearing masks. All of them black.

Drama Queen Disability and Workman's Comp Prepping. Same thing happened at our post office during the swine flu scare, gloves 'n masks and posturing. The Filipinos, Chinese and white people just kept on working, no masks or gloves.

I think you may have missed his joke. The "Black men wearing masks" were bandits.

www.youtube.com/embed/MPGw5Ucmwk8