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Corona virus (more correctly, Wuhan virus)


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2020 Jan 24, 12:33pm   187,616 views  3,363 comments

by Heraclitusstudent   ➕follow (8)   💰tip   ignore  

Anyone wants to risk a bet on the eventual number of sick people? Dead people?

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961   zzyzzx   2020 Mar 18, 12:57pm  

https://baltimore.cbslocal.com/2020/03/18/we-need-those-beds-baltimore-mayor-urges-people-to-put-down-guns-after-violence-continues-during-covid-19-pandemic/

Baltimore Mayor Begs Residents To Stop Shooting Each Other So Hospital Beds Can Be Used For Coronavirus Patients

BALTIMORE (WJZ) — Baltimore Mayor Jack Young urged residents to put down their guns and heed orders to stay home after multiple people were shot Tuesday night amidst the coronavirus pandemic.
962   Patrick   2020 Mar 18, 1:02pm  

Patrick says
OK, now what exactly is the name of the obsolete HIV drug that cures coronavirus, and who owns the patent?


The Australians didn't say, but other sites say that one drug is a combination: lopinavir/ritonavir (marketed as Kaletra or Aluvia, and patent expired in 2016!), and another is called remdesivir.

https://en.wikipedia.org/wiki/Lopinavir/ritonavir

https://en.wikipedia.org/wiki/Remdesivir

In late January 2020, remdesivir was administered to the first US patient to be confirmed to be infected by SARS-CoV-2, in Snohomish County, Washington, for "compassionate use" after he progressed to pneumonia. While no broad conclusions were made based on the single treatment, the patient's condition improved dramatically the next day,[7] and he was eventually discharged.[19]

Also in late January 2020, Chinese medical researchers stated to the media that in exploratory research considering a selection of 30 drug candidates, remdesivir and two other drugs, chloroquine and lopinavir/ritonavir, seemed to have "fairly good inhibitory effects" on SARS-CoV-2 at the cellular level. Requests to start clinical testing were submitted.[20][21] On February 6, 2020, a clinical trial of remdesivir began in China.[22]

On 17 March 2020, remdesivir was provisionally approved for use for COVID19 patients in a serious condition in the Czech Republic.[23]

On 18 March 2020, the first italian COVID-19 patient was successfully cured with remdesivir. [24]


Damn, that was just today.
963   HeadSet   2020 Mar 18, 1:45pm  

On 18 March 2020, the first italian COVID-19 patient was successfully cured with remdesivir. [24]


Damn, that was just today.


You will know this is true if the Dow shoots up tomorrow.
964   HeadSet   2020 Mar 18, 1:46pm  

Baltimore Mayor Begs Residents To Stop Shooting Each Other So Hospital Beds Can Be Used For Coronavirus Patients.

What he really meant was , "If you shoot, be sure to kill."
968   marcus   2020 Mar 18, 2:33pm  

Patrick says
In late January 2020, remdesivir was administered to the first US patient to be confirmed to be infected by SARS-CoV-2, in Snohomish County, Washington, for "compassionate use" after he progressed to pneumonia. While no broad conclusions were made based on the single treatment, the patient's condition improved dramatically the next day,[7] and he was eventually discharged.[19]


One would think this would lead or would have led to rogue doctors using it more. I wonder how that works, if a drug that hasn't been approved for certain use is known to work. Does word get around ? It must right ?
969   RWSGFY   2020 Mar 18, 2:42pm  

marcus says
I wonder how that works, if a drug that hasn't been approved for certain use is known to work. Does word get around ? It must right ?


It was until all bars got shut down ....
970   Patrick   2020 Mar 18, 3:05pm  

marcus says
One would think this would lead or would have led to rogue doctors using it more. I wonder how that works, if a drug that hasn't been approved for certain use is known to work. Does word get around ? It must right ?


The Chinese guy who brought the disease to Seattle was cured when he had severe pneumonia and it was allowed out of "compassionate use". There seem to be exceptions like that.

As for word getting out, sure, doctors talk, and maybe this very post is helping.
971   MisdemeanorRebel   2020 Mar 18, 3:45pm  

BALTIMORE (WJZ) — Baltimore Mayor Jack Young urged residents to put down their guns and heed orders to stay home after multiple people were shot Tuesday night amidst the coronavirus pandemic.

Young said hospital beds are needed to treat positive COVID-19 patients and not for senseless violence. Seven people were shot Tuesday night in the Madison Park neighborhood, as Baltimore reported its fifth positive coronavirus case Wednesday.

“I want to reiterate how completely unacceptable the level of violence is that we have seen recently,” Young said. “We will not stand for mass shootings and an increase in crime.”
https://baltimore.cbslocal.com/2020/03/18/we-need-those-beds-baltimore-mayor-urges-people-to-put-down-guns-after-violence-continues-during-covid-19-pandemic/
972   FuckTheMainstreamMedia   2020 Mar 18, 4:03pm  

NoCoupForYou says
BALTIMORE (WJZ) — Baltimore Mayor Jack Young urged residents to put down their guns and heed orders to stay home after multiple people were shot Tuesday night amidst the coronavirus pandemic.

Young said hospital beds are needed to treat positive COVID-19 patients and not for senseless violence. Seven people were shot Tuesday night in the Madison Park neighborhood, as Baltimore reported its fifth positive coronavirus case Wednesday.

“I want to reiterate how completely unacceptable the level of violence is that we have seen recently,” Young said. “We will not stand for mass shootings and an increase in crime.”
https://baltimore.cbslocal.com/2020/03/18/we-need-those-beds-baltimore-mayor-urges-people-to-put-down-guns-after-violence-continues-during-covid-19-pandemic/


I mean they could have been out arresting Obama’s sons in the severa years prior to this.
973   socal2   2020 Mar 18, 4:23pm  

This is from 2007.
https://cmr.asm.org/content/cmr/20/4/660.full.pdf

Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) is a novel virus that caused the first major pandemic of the new millennium (89, 180, 259). The rapid economic growth in southern China has led to an increasing demand for animal proteins including those from exotic game food animals such as civets. Large numbers and varieties of these wild game mammals in overcrowded cages and the lack of biosecurity measures in wet markets allowed the jumping of this novel virus from animals to human (353, 376). Its capacity for human-to-human transmission, the lack of awareness in hospital infection control, and international air travel facilitated the rapid global dissemination of this agent.

Coronaviruses are well known to undergo genetic recombination (375), which may lead to new genotypes and outbreaks. The presence of a large reservoir of SARS-CoV-like viruses in horseshoe bats, together with the culture of eating exotic mammals in southern China, is a time bomb. The possibility of the reemergence of SARS and other novel viruses from animals or laboratories and therefore the need for preparedness should not be ignored.
975   Ceffer   2020 Mar 18, 5:15pm  

CovfefeButDeadly says

“I want to reiterate how completely unacceptable the level of violence is that we have seen recently,” Young said. “We will not stand for mass shootings and an increase in crime.”


Yeah, lip service will get it done. You don't like those suitcases full of cash from the drug lords?
976   Patrick   2020 Mar 18, 6:14pm  

Many good things are happening because of coronavirus:

Germany Stops Refugee Program (9:34 a.m. NY)
Germany has stopped the resettlement program for refugees as part of the government’s measures against the coronavirus, a spokesman for the interior ministry said on Wednesday. As part of the EU-Turkey agreement, Germany has taken in refugees from Syria and Turkey since 2012.


Many borders being closed, countries becoming acutely away of the massive hidden harm of dependency on China and similar countries, illegals out of work with restaurants closed, international flights now justifiably suspect as disease vectors, and on and on.

Now if only it would take out Saudi Arabia.
977   Onvacation   2020 Mar 18, 7:52pm  

What was the first thing people picked up during the panic shopping?

Cases of Corona.
978   RC2006   2020 Mar 18, 7:53pm  

No surprise on what city has the most.
980   Patrick   2020 Mar 18, 8:40pm  

https://www.sciencedirect.com/science/article/pii/S0924857920300662

The novel coronavirus currently isolated in China has been, with staggering speed, evaluated regarding its sensitivity to already used drugs [12]. Thus, the new antiviral drug remdesivir [13] as well as chloroquine, at an EC50 of 1.1 µM, were found to be effective in preventing replication of this virus [12]. Chloroquine is perhaps one of the most prescribed drugs in the world [14,15]. As a matter of fact, all Europeans visiting malaria-endemic geographic areas for decades received chloroquine prophylaxis and continued it for 2 months after their return. In addition, local residents took chloroquine continuously, and treatment of malaria has long been based on this drug. In addition, hydroxychloroquine has been used for decades at much higher doses (up to 600 mg/day) to treat autoimmune diseases [16]. It is difficult to find a product that currently has a better established safety profile than chloroquine. Furthermore, its cost is negligible.
981   Patrick   2020 Mar 18, 8:55pm  

The Chinese say so too:

http://english.www.gov.cn/statecouncil/ministries/202002/17/content_WS5e4a944dc6d0595e03c20f35.html

BEIJING — Chinese experts, based on the result of clinical trials, have confirmed that Chloroquine Phosphate, an antimalarial drug, has a certain curative effect on the novel coronavirus disease (COVID-19), a Chinese official said here on Feb 17.

The experts have "unanimously" suggested the drug be included in the next version of the treatment guidelines and applied in wider clinical trials as soon as possible, Sun Yanrong, deputy head of the China National Center for Biotechnology Development under the Ministry of Science and Technology, said at a press conference.

Chloroquine Phosphate, which has been used for more than 70 years, was selected from tens of thousands of existing drugs after multiple rounds of screening, Sun said.

According to her, the drug has been under clinical trials in over 10 hospitals in Beijing, as well as in South China's Guangdong province and Central China's Hunan province, and has shown fairly good efficacy.

In the trials, the groups of patients that have taken the drug have shown better indicators than their parallel groups, in abatement of fever, improvement of CT images of lungs, the percentage of patients who became negative in viral nucleic acid tests and the time they need to do so, she said.

Patients taking the drug also take shorter time to recover, she added.

Sun gave an example of a 54-year-old patient in Beijing, who was admitted to hospital four days after showing symptoms. After taking the drug for a week, he saw all indicators improve and the nucleic acid turn negative.

So far, no obvious serious adverse reactions related to the drug have been found among the over 100 patients enrolled in the clinical trials, she said.
982   SoTex   2020 Mar 18, 9:00pm  

WookieMan says
I wonder if the couples cam porn industry is going to boom now?


We're finally gonna get a baby boom out of these millennials!
983   FortWayneAsNancyPelosiHaircut   2020 Mar 18, 9:12pm  

Tarzana Medical Center right now is full with Corona patients, one is a doctor. Those numbers are not yet reported. But they went up a lot lately.
984   SoTex   2020 Mar 18, 9:25pm  

I started listening to the local 10PM news broadcast on the TV the past 2 days. I haven't done that in a few years.
985   RWSGFY   2020 Mar 19, 8:24am  

A Coronavirus Explosion Was Expected in Japan. Where Is It?

Japan was one of first countries outside of China hit by the coronavirus and now it’s one of the least-affected among developed nations. That’s puzzling health experts.
Unlike China’s draconian isolation measures, the mass quarantine in much of Europe and big U.S. cities ordering people to shelter in place, Japan has imposed no lockdown. While there have been disruptions caused by school closures, life continues as normal for much of the population. Tokyo rush hour trains are still packed and restaurants remain open.
The looming question is whether Japan has dodged a bullet or is about to be hit.

....

“Italy’s mortality rate is almost triple Japan’s,” said Yoko Tsukamoto, a professor of infection control at the Health Sciences University of Hokkaido. “Part of the reason is if you get tested, you get quarantined, so it means that they don’t have enough beds for relatively non-severe patients.”
Japan has tested more than 15,000 people as of Wednesday, and despite discouraging checks on those who don’t have symptoms or contact with a carrier, the infection rate lies at 5.6%. That compares to around 3% in South Korea, but 18% in Italy.
“We don’t see a need to use all of our testing capacity, just because we have it,” Health Ministry official Yasuyuki Sahara said at a briefing Tuesday. “Neither do we think it’s necessary to test people just because they’re worried.”

....


https://apple.news/AGmpWO7u_TGK0WtLBco5A7g
987   Patrick   2020 Mar 19, 8:50am  

https://www.nature.com/articles/d41586-020-00758-2

How does COVID-19 compare to other diseases?
Current estimates of COVID-19’s case fatality rate — a measure of the proportion of infected people who eventually die — suggest that the coronavirus is less deadly than the pathogens behind other large-scale outbreaks, such as of SARS (severe acute respiratory syndrome), MERS (Middle East respiratory syndrome) and Ebola.

But the infection also seems to spread more easily than other diseases, including seasonal influenza. Calculations of the virus’s basic reproduction number, or R0 — the number of people on average one infected person will pass the virus to — suggest a range of 2–2.5.


989   mell   2020 Mar 19, 6:20pm  

TEOTWAWKI says
A Coronavirus Explosion Was Expected in Japan. Where Is It?

Japan was one of first countries outside of China hit by the coronavirus and now it’s one of the least-affected among developed nations. That’s puzzling health experts.
Unlike China’s draconian isolation measures, the mass quarantine in much of Europe and big U.S. cities ordering people to shelter in place, Japan has imposed no lockdown. While there have been disruptions caused by school closures, life continues as normal for much of the population. Tokyo rush hour trains are still packed and restaurants remain open.
The looming question is whether Japan has dodged a bullet or is about to be hit.

....

“Italy’s mortality rate is almost triple Japan’s,” said Yoko Tsukamoto, a professor of infection control at the Health Sciences University of Hokkaido. “Part of the reason is if you get tested, you get quarantined, so it means that they don’t have enough beds for relatively non-severe patients....


Well you know why. The Japanese are polite and clean. Basic hygiene and manners go a long way.
993   Patrick   2020 Mar 19, 10:45pm  

Strangely, the general health of the public gets better during depressions:

Recent events highlight the importance of examining the impact of economic downturns on population health. The Great Depression of the 1930s was the most important economic downturn in the U.S. in the twentieth century. We used historical life expectancy and mortality data to examine associations of economic growth with population health for the period 1920–1940. We conducted descriptive analyses of trends and examined associations between annual changes in health indicators and annual changes in economic activity using correlations and regression models. Population health did not decline and indeed generally improved during the 4 years of the Great Depression, 1930–1933, with mortality decreasing for almost all ages, and life expectancy increasing by several years in males, females, whites, and nonwhites. For most age groups, mortality tended to peak during years of strong economic expansion (such as 1923, 1926, 1929, and 1936–1937). In contrast, the recessions of 1921, 1930–1933, and 1938 coincided with declines in mortality and gains in life expectancy. The only exception was suicide mortality which increased during the Great Depression, but accounted for less than 2% of deaths. Correlation and regression analyses confirmed a significant negative effect of economic expansions on health gains. The evolution of population health during the years 1920–1940 confirms the counterintuitive hypothesis that, as in other historical periods and market economies, population health tends to evolve better during recessions than in expansions.


https://www.pnas.org/content/106/41/17290
994   Patrick   2020 Mar 20, 8:23am  

Huh, Wuhan virus disproportionately affects areas that vote for globalist Democrats. Karma at work?

To be certain, COVID-19 is hammering the entire U.S., regardless of geographic location or political affiliation. And the coming economic calamity is expected to leave no industry or region unscathed.

Yet as the virus brings activity on both coasts — which overwhelmingly voted for Hillary Clinton in 2016 — to a grinding halt, the demographics underscore how Democratic areas are being more heavily impacted than Republican ones. ...

According to the CDC, there are over 4,600 confirmed cases in New York State, and in New York City, there are nearly 4,000 infections and rising. That was double the figures that had been released just the day prior.

Meanwhile the partisan skew is obvious: The unabashedly liberal Big Apple hasn’t voted for a Republican president since 1924; and in 2016, Clinton won roughly 87% of Manhattan’s vote against fellow New York resident Donald Trump.


https://finance.yahoo.com/news/coronavirus-hitting-democrat-communities-more-than-republican-ones-143813828.html
995   NDrLoR   2020 Mar 20, 8:30am  

Patrick says
Wuhan virus disproportionately affects areas that vote for globalist Democrats
Yes, I noticed that, while the disgusting flyover country is relatively mild.

https://www.livescience.com/coronavirus-updates-united-states.html
996   Patrick   2020 Mar 20, 8:44am  

Also, this mass self-quarantine may wipe out certain strains of cold, flu, and other diseases because the chains of transmission are being broken.

Hell, venereal diseases will probably also decrease for the same reason.

And even though the economy is getting whacked, many countries have lived through economic devastation before and then rebounded. Could take years, but things will recover.
997   Patrick   2020 Mar 20, 8:54am  

Lol, the rich are getting access to Wuhan virus tests ahead of everyone else:

https://www.cnbc.com/2020/03/20/how-one-elite-new-york-medical-provider-got-its-patients-coronavirus-tests.html

Not surprising.
998   Patrick   2020 Mar 20, 8:56am  

More about the French experience with chloroquine:

This week, French researchers released results from a preliminary trial using 36 COVID-19 patients. The study, headed by Didier Raoult from Aix-Marseille University in France, has not yet been peer-reviewed but shows promising results.Twenty of the patients received 600 milligrams of hydroxychloroquine daily, and the remainder did not to act as a control group.After six days, 70% of the patients who received the drug were considered cured, compared with only 12.5% of the control group, according to Newsweek.
999   RWSGFY   2020 Mar 20, 9:03am  

Patrick says
Huh, Wuhan virus disproportionately affects areas that vote for globalist Democrats. Karma at work?


Not karma: just density, public transportation, uncontrolled immigration, outsized homeless population, etc.
1000   RWSGFY   2020 Mar 20, 9:04am  

Patrick says
Lol, the rich are getting access to Wuhan virus tests ahead of everyone else


Test-shmest. I fail to see a point for an individual to test for that shit: if your symptoms are mild just ride it out, if they are severe - get hospitalized.

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