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Ivermectin


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2021 May 9, 10:24pm   85,125 views  659 comments

by Patrick   ➕follow (60)   💰tip   ignore  

https://sebastianrushworth.com/2021/05/09/update-on-ivermectin-for-covid-19/

Back in January I wrote an article about four randomized controlled trials of ivermectin as a treatment for covid-19 that had at that time released their results to the public. Each of those four trials had promising results, but each was also too small individually to show any meaningful impact on the hard outcomes we really care about, like death. When I meta-analyzed them together however, the results suddenly appeared very impressive. Here’s what that meta-analysis looked like:



It showed a massive 78% reduction in mortality in patients treated with covid-19. Mortality is the hardest of hard end points, which means it’s the hardest for researchers to manipulate and therefore the least open to bias. Either someone’s dead, or they’re alive. End of story.

You would have thought that this strong overall signal of benefit in the midst of a pandemic would have mobilized the powers that be to arrange multiple large randomized trials to confirm these results as quickly as possible, and that the major medical journals would be falling over each other to be the first to publish these studies.

That hasn’t happened.

Rather the opposite, in fact. South Africa has even gone so far as to ban doctors from using ivermectin on covid-19 patients. And as far as I can tell, most of the discussion about ivermectin in mainstream media (and in the medical press) has centred not around its relative merits, but more around how its proponents are clearly deluded tin foil hat wearing crazies who are using social media to manipulate the masses.

In spite of this, trial results have continued to appear. That means we should now be able to conclude with even greater certainty whether or not ivermectin is effective against covid-19. Since there are so many of these trials popping up now, I’ve decided to limit the discussion here only to the ones I’ve been able to find that had at least 150 participants, and that compared ivermectin to placebo (although I’ll add even the smaller trials I’ve found in to the updated meta-analysis at the end).

As before, it appears that rich western countries have very little interest in studying ivermectin as a treatment for covid. The three new trials that had at least 150 participants and compared ivermectin with placebo were conducted in Colombia, Iran, and Argentina. We’ll go through each in turn. ...

What we see is a 62% reduction in the relative risk of dying among covid patients treated with ivermectin. That would mean that ivermectin prevents roughly three out of five covid deaths. The reduction is statistically significant (p-value 0,004). In other words, the weight of evidence supporting ivermectin continues to pile up. It is now far stronger than the evidence that led to widespred use of remdesivir earlier in the pandemic, and the effect is much larger and more important (remdesivir was only ever shown to marginally decrease length of hospital stay, it was never shown to have any effect on risk of dying).

I understand why pharmaceutical companies don’t like ivermectin. It’s a cheap generic drug. Even Merck, the company that invented ivermectin, is doing it’s best to destroy the drug’s reputation at the moment. This can only be explained by the fact that Merck is currently developing two expensive new covid drugs, and doesn’t want an off-patent drug, which it can no longer make any profit from, competing with them.

The only reason I can think to understand why the broader medical establishment, however, is still so anti-ivermectin is that these studies have all been done outside the rich west. Apparently doctors and scientists outside North America and Western Europe can’t be trusted, unless they’re saying things that are in line with our pre-conceived notions.


And HCQ falls into that same bucket. Even worse - to admit HCQ works would be to admit Trump was right about something.

Liberals would rather that millions die than that Trump be allowed to be right about anything. They hate Trump more than they love their fellow humans.

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627   Patrick   2024 Oct 13, 1:30pm  

https://pubmed.ncbi.nlm.nih.gov/29257278/


Ivermectin as an inhibitor of cancer stem‑like cells

The aim of the present study was to demonstrate that ivermectin preferentially inhibited cancer stem‑like cells (CSC) in breast cancer cells and downregulated the expression of 'stemness' genes. Computational searching of DrugBank, a database of approved drugs, was performed using the principles of two‑dimensional similarity searching; the chemical structure of salinomycin was used as a query. Growth inhibition of the breast cancer cell lin e MDA‑MB‑231 by ivermectin was investigated in the total cell population, in cell spheroids and in sorted cells that expressed cluster of differentiation (CD)44+/CD24‑. The effects of ivermectin treatment on the expression of pluripotency and self‑renewal transcription factors, such as homeobox protein nanog (nanog), octamer‑binding protein 4 (oct‑4) and SRY‑box 2 (sox‑2), were evaluated by reverse transcription‑quantitative polymerase chain reaction and western blotting. Ivermectin exhibited a similarity value of 0.78 in reference to salinomycin. Ivermectin demonstrated an inhibitory effect upon the growth of MDA‑MB‑231 cells in the range of 0.2‑8 µM. Ivermectin preferentially inhibits the viability of CSC‑enriched populations (CD44+/CD24‑ and cells growing in spheroids) compared with the total cell population. The opposite pattern was observed with paclitaxel treatment. Ivermectin exposure reduced the expression of nanog, oct‑4 and sox‑2 at the mRNA and protein levels. Ivermectin preferentially inhibited the CSC subpopulation in the MDA‑MB‑231 cells and downregulated the expression of genes involved in the maintenance of pluripotency and self‑renewal.
632   stereotomy   2025 Feb 2, 8:01pm  

The_Deplorable says

https://x.com/VigilantFox/status/1862727748189401143

Fenbendazole (the drugs approved for human use are mebendazole and abendazole) is an antiparasitic most commonly used as a dog dewormer, and sold under the name Panacur, produced by Merck. It's available everywhere - just search for "panacur."
634   Maga_Chaos_Monkey   2025 Feb 9, 7:51pm  

stereotomy says

Fenbendazole (the drugs approved for human use are mebendazole and abendazole) is an antiparasitic most commonly used as a dog dewormer, and sold under the name Panacur, produced by Merck. It's available everywhere - just search for "panacur."


I use it for my marine fish when they are in quarantine.
635   AmericanKulak   2025 Feb 9, 7:57pm  

The_Deplorable says




https://jonfleetwood.substack.com/p/arkansas-bill-would-make-ivermectin

All non-opiate, non-psychoactive, and non-Black Label drugs should be over the counter.

There is no 4th branch of government called "Professional Associations"
636   Maga_Chaos_Monkey   2025 Feb 9, 8:01pm  

Maga_Chaos_Monkey says

stereotomy says


Fenbendazole (the drugs approved for human use are mebendazole and abendazole) is an antiparasitic most commonly used as a dog dewormer, and sold under the name Panacur, produced by Merck. It's available everywhere - just search for "panacur."


I use it for my marine fish when they are in quarantine.


Tryptophan microtubule crystals may in fact be the source of consciousness with quantum interactions. In vitro the quantum interactions have already been proven pretty recently.
639   iloveCefferMemes   2025 Feb 9, 10:57pm  

Maga_Chaos_Monkey says

Tryptophan microtubule crystals may in fact be the source of consciousness with quantum interactions


I had no idea tryptophan had such unique properties.
Found this article, with both audio and text. A tad bit robotic and repetitive. Good images.

Long-range Collective Quantum Coherence in Tryptophan Mega-Networks of Biological Architectures,
https://spacefed.com/biology/long-range-collective-quantum-coherence-in-tryptophan-mega-networks-of-biological-architectures/

Origins of consciousness (before life) is fun to ponder. I was listening to an interview with E. Witten in 2023. He thinks consciousness will remain a permanent mystery.
640   Al_Sharpton_for_President   2025 Feb 10, 6:57am  

iloveCefferMemes says

He thinks consciousness will remain a permanent mystery.

How can you study consciousness with consciousness?
641   HeadSet   2025 Feb 10, 2:03pm  

Al_Sharpton_for_President says

How can you study consciousness with consciousness?

Subconsciously.
645   Maga_Chaos_Monkey   2025 Feb 22, 10:12pm  

https://allfamilypharmacy.com/

Seems like a good legal place to get Ivermectin and the prices are reasonable:

3350 NW 2nd Ave Suite A34
Boca Raton, FL 33431

Lots of great reviews. There was a $20 physician screening fee to get the prescription. It's a weekend so my order hasn't been handled yet. A real brick and mortar US location.

All Family Pharmacy

is a family owned licensed pharmacy located in Boca Raton, Florida. We work with doctors all over the country to help get access to medications normal pharmacies don't or are unwilling to dispense including but not limited to Ivermectin and Hydroxychloroquine. All orders include a prescription from our licensed doctors.
646   stereotomy   2025 Feb 23, 9:45am  

Maga_Chaos_Monkey says


https://allfamilypharmacy.com/

Seems like a good legal place to get Ivermectin and the prices are reasonable:

3350 NW 2nd Ave Suite A34
Boca Raton, FL 33431

Lots of great reviews. There was a $20 physician screening fee to get the prescription. It's a weekend so my order hasn't been handled yet. A real brick and mortar US location.

All Family Pharmacy

is a family owned licensed pharmacy located in Boca Raton, Florida. We work with doctors all over the country to help get access to medications normal pharmacies don't or are unwilling to dispense including but not limited to Ivermectin and Hydroxychloroquine. All orders include a prescription from our licensed doctors.

I guess it's good that there are legit US sources for ivermectin, but $5 per pill for 12 mg? You can get 100 packs of 12 mg ivermectin for $100 at Alldaychemist.

However, if the de minimus exemption for postal packages is ended, bye bye Alldaychemist. All Family is much more expensive, but you don't have to worry about Customs inspections, and you get the fig leaf of a doctor's prescription.
647   Maga_Chaos_Monkey   2025 Feb 23, 10:15am  

stereotomy says

I guess it's good that there are legit US sources for ivermectin, but $5 per pill for 12 mg? You can get 100 packs of 12 mg ivermectin for $100 at Alldaychemist.

However, if the de minimus exemption for postal packages is ended, bye bye Alldaychemist. All Family is much more expensive, but you don't have to worry about Customs inspections, and you get the fig leaf of a doctor's prescription.


No shiite! I hadn't heard of them - will check them out!
649   Glock-n-Load   2025 Mar 11, 5:31am  

Where can I get antibiotics?
650   The_Deplorable   2025 Mar 11, 5:39pm  

Glock-n-Load says
"Where can I get antibiotics?"

In my thinking you do not need antibiotics unless you have an actual bacterial
infection. Just take your prophylactic medications - HCQ, Ivermectin, Artemisinin
etc.
651   stereotomy   2025 Mar 13, 10:51am  

Glock-n-Load says

Where can I get antibiotics?

alldaychemist.com
652   stereotomy   2025 Mar 13, 10:57am  

If I need antibiotics I usually hit the z-pack, since it only takes 3 days to kick in as opposed to 7-10 days for the others.

There's a nasty sinus infection going around. The 'mectin + @Rin cocktail beat it down, but not enough for me to completey kick it. I had to add a z-pack to finally get rid of it.
654   stereotomy   2025 Mar 26, 5:27pm  

I already have convinced one friend about the 'mectin + @Rin cocktail. Now I'll be hooking up another friend.

The silver lining with the scamdemic was that I finally became so fucking enraged, which motivated me to take complete control over my family's health, and now that choice is allowing me to help friends as needed.
655   Patrick   2025 Mar 28, 2:13pm  

https://www.kark.com/news/politics/gov-sarah-huckabee-sanders-signs-over-the-counter-ivermectin-sales-bill-into-law/


Gov. Sarah Huckabee Sanders signs over-the-counter ivermectin sales bill into law

Legislation approving ivermectin for human use without a prescription has been signed into law.

Gov. Sarah Huckabee Sanders signed Senate Bill 189 into law Tuesday.

The legislation states that, “ivermectin suitable for human use may be sold or purchased as an over-the-counter medication in this state without a prescription or consultation with a healthcare professional.” ...

Despite the U.S. Food and Drug Administration opposing its use, it became a popular alternate treatment for vaccine opponents during the COVID-19 pandemic.


Yes, because it works and because it's safer than aspirin. That cheapness and safety threatened the $100 billion that Pfizer charged for the dangerous and worse-than-ineffective mRNA death jabs. So the criminally corrupt FDA chose to protect Pfizer profits instead of human lives.
656   Patrick   2025 Mar 28, 2:15pm  

https://www.coffeeandcovid.com/p/accountability-robots-friday-march


It’s not over yet. The FDA has not approved ivermectin for OTC sale. So some Arkansan pharmacists may avoid carrying it over the counter and will still require a prescription. The FDA should either approve the drug for OTC sale, or change the rules so states can decide. I am sure FDA officials have heard about Arkansas’s new law. It’s their move.


Hopefully Trump's FDA will be less criminal that the FDA under Biden.
657   stereotomy   2025 Mar 28, 7:00pm  

Just hit up alldaychemist. Although, I don't know how the tariffs and de minimus shipping changes will affect things. I loaded up right before TSHTF.
658   Maga_Chaos_Monkey   2025 Mar 29, 11:54am  

allfamilypharmacy worked out well, with refills. Took about a week to arrive but you can pay extra for overnight.

I tried Redbox Rx too and they also worked out well.

Probably more expensive but no concern of shipping from outside of the US.

This basically:

stereotomy says

All Family is much more expensive, but you don't have to worry about Customs inspections, and you get the fig leaf of a doctor's prescription.

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