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Ivermectin

By Patrick follow Patrick   2021 May 9, 10:24pm 2,930 views   258 comments   watch   nsfw   quote   share    


https://sebastianrushworth.com/2021/05/09/update-on-ivermectin-for-covid-19/

Back in January I wrote an article about four randomized controlled trials of ivermectin as a treatment for covid-19 that had at that time released their results to the public. Each of those four trials had promising results, but each was also too small individually to show any meaningful impact on the hard outcomes we really care about, like death. When I meta-analyzed them together however, the results suddenly appeared very impressive. Here’s what that meta-analysis looked like:



It showed a massive 78% reduction in mortality in patients treated with covid-19. Mortality is the hardest of hard end points, which means it’s the hardest for researchers to manipulate and therefore the least open to bias. Either someone’s dead, or they’re alive. End of story.

You would have thought that this strong overall signal of benefit in the midst of a pandemic would have mobilized the powers that be to arrange multiple large randomized trials to confirm these results as quickly as possible, and that the major medical journals would be falling over each other to be the first to publish these studies.

That hasn’t happened.

Rather the opposite, in fact. South Africa has even gone so far as to ban doctors from using ivermectin on covid-19 patients. And as far as I can tell, most of the discussion about ivermectin in mainstream media (and in the medical press) has centred not around its relative merits, but more around how its proponents are clearly deluded tin foil hat wearing crazies who are using social media to manipulate the masses.

In spite of this, trial results have continued to appear. That means we should now be able to conclude with even greater certainty whether or not ivermectin is effective against covid-19. Since there are so many of these trials popping up now, I’ve decided to limit the discussion here only to the ones I’ve been able to find that had at least 150 participants, and that compared ivermectin to placebo (although I’ll add even the smaller trials I’ve found in to the updated meta-analysis at the end).

As before, it appears that rich western countries have very little interest in studying ivermectin as a treatment for covid. The three new trials that had at least 150 participants and compared ivermectin with placebo were conducted in Colombia, Iran, and Argentina. We’ll go through each in turn. ...

What we see is a 62% reduction in the relative risk of dying among covid patients treated with ivermectin. That would mean that ivermectin prevents roughly three out of five covid deaths. The reduction is statistically significant (p-value 0,004). In other words, the weight of evidence supporting ivermectin continues to pile up. It is now far stronger than the evidence that led to widespred use of remdesivir earlier in the pandemic, and the effect is much larger and more important (remdesivir was only ever shown to marginally decrease length of hospital stay, it was never shown to have any effect on risk of dying).

I understand why pharmaceutical companies don’t like ivermectin. It’s a cheap generic drug. Even Merck, the company that invented ivermectin, is doing it’s best to destroy the drug’s reputation at the moment. This can only be explained by the fact that Merck is currently developing two expensive new covid drugs, and doesn’t want an off-patent drug, which it can no longer make any profit from, competing with them.

The only reason I can think to understand why the broader medical establishment, however, is still so anti-ivermectin is that these studies have all been done outside the rich west. Apparently doctors and scientists outside North America and Western Europe can’t be trusted, unless they’re saying things that are in line with our pre-conceived notions.


And HCQ falls into that same bucket. Even worse - to admit HCQ works would be to admit Trump was right about something.

Liberals would rather that millions die than that Trump be allowed to be right about anything. They hate Trump more than they love their fellow humans.

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219   just_passing_through   ignore (8)   2021 Sep 12, 5:48pm     ↓ dislike (0)   quote   flag      

Patrick says
I really like turmeric too.


I have a big bin of it but to make it work pharmaceutically it needs to be fresh and mine isn't. Buy the root and grind it yourself and eat it within 2-3 weeks. The sooner the better.

Otherwise it's just adding color and flavor.
220   Patrick   ignore (1)   2021 Sep 12, 5:51pm     ↓ dislike (0)   quote   flag      

just_passing_through says
Eat butter too. And olive oil, coconut oil, avacado oil and beef tallow.



I am a convert to your religion!

They all sound good to me.

I like fresh turmeric too, it's kind of like ginger.
221   just_passing_through   ignore (8)   2021 Sep 12, 5:58pm     ↓ dislike (0)   quote   flag      

I lost a lot of weight switching to real animal fats and lowering my carbs, my cooking got better and I eat less because I'm satiated quicker and longer. I can actually fast for long periods quite easily now that my body learned to burn fat.

Carb addicts may have a hard time at first until their body is retrained. It takes a while. Fortunately I've always sort of eaten that way so it wasn't hard for me.

Lately I've been eating broccoli sprouts daily. #1 super food. I grow it in mason jars. Check out some of Dr. Rhonda Patrick's videos. She's pretty awesome.
222   Patrick   ignore (1)   2021 Sep 12, 5:59pm     ↓ dislike (0)   quote   flag      

I'm trying to eat nothing with any cane sugar in it for all of September.

It's rather difficult. I think I'm making it up in alcohol.
223   just_passing_through   ignore (8)   2021 Sep 12, 6:00pm     ↓ dislike (0)   quote   flag      

Oh, and fish oil. I just supplement with that or eat fish. Lately lots of shrimp too to counteract any iodine issues from the broccoli sprouts. I should really start eating smoked oysters for zinc or something.
224   Patrick   ignore (1)   2021 Sep 12, 6:02pm     ↓ dislike (0)   quote   flag      

I still tend to eat fish on Friday, just because it was a thing when I was growing up. And because I like fish.
225   HeadSet   ignore (3)   2021 Sep 12, 7:59pm     ↓ dislike (0)   quote   flag      

just_passing_through says
Eat butter too. And olive oil, coconut oil, avacado oil and beef tallow.

Coconut oil is on the good list? I thought is was as bad as vegetable oil. Coconut oil has cooking advantages, so I want it to be healthy.
226   Shaman   ignore (2)   2021 Sep 12, 8:32pm     ↓ dislike (0)   quote   flag      

My dietician wife says coconut oil is fine.
We use it for cooking a fair bit.
227   Patrick   ignore (1)   2021 Sep 12, 10:07pm     ↓ dislike (0)   quote   flag      

It makes good popcorn.
228   just_passing_through   ignore (8)   2021 Sep 13, 5:13am     ↓ dislike (0)   quote   flag      

Ghee and clarified butter have a relatively high smoke point.
230   Karloff   ignore (0)   2021 Sep 13, 1:49pm     ↓ dislike (0)   quote   flag      

There's accusations that hospitals in Australia are now treating vaxxed covid patients with Ivermectin, but not unvaxxed.

https://gab.com/Arturo1960/posts/106921705547994992

Evil, murderous swine if this is true.
233   Rin   ignore (9)   2021 Sep 14, 10:32am     ↓ dislike (0)   quote   flag      

just_passing_through says
Buy the root and grind it yourself and eat it within 2-3 weeks.


I have an herbalist in Boston do that for me, every month with fresh peppercorn and olive oil.
234   mell   ignore (6)   2021 Sep 14, 4:59pm     ↓ dislike (0)   quote   flag      

Got all my covid emergency meds from India, nice mix of the most effective and safe, will go to the !covid! war-chest and last for years. Just in case of an emergency...
Neigh!
235   Patrick   ignore (1)   2021 Sep 14, 10:54pm     ↓ dislike (0)   quote   flag      

https://www.thedesertreview.com/opinion/columnists/the-ivermectin-deworming-hoax---part-ii-eric-clapton-s-human-rights-warning/article_284902bc-14be-11ec-8d43-43e98275cff8.html

On September 10, 2021, Uttarakhand had just 20 new cases in a population of 11.4 million, or about two cases for every million people. They had ZERO new deaths. Goa had 45 cases and two deaths, while Kerala had 25,010 new cases and 177 new deaths.

Other Indian states also decided to go "all-in" on Ivermectin, and they did exceedingly well. So, on September 10, these are the numbers of the other Ivermectin-using Indian states.

This data was compiled by the Johns Hopkins University Center for Systems Science and Engineering – the JHU CSSE.

https://systems.jhu.edu/

On September 10, 2021, Uttar Pradesh, a population of 240 million, saw nine new cases, or about one for every 24 million people. One death. Delhi saw only 36 new cases and ZERO deaths. Bihar, a population of 127 million, saw 12 new cases, or one per 10 million population. ZERO deaths.

In stark contrast, we see Kerala, a population of 34 million people, with 25,010 new cases on September 10, or nearly one per thousand. Deaths are 177 out of the entire country's total of 308. Thus, more than half of all of India's September 10 COVID deaths occurred in Kerala.

This debacle occurred despite Kerala being among the most vaccinated states in all of India. The Chief Minister proudly reports that 93 percent of Kerala's residents over 45 have one vaccination while 50 percent are fully vaccinated.

https://m.economictimes.com/news/india/kerala-to-complete-vaccination-of-all-above-18-years-by-september-30-cm-pinarayi-vijayan/articleshow/86100022.cms

Like Kerala, the United Kingdom is "all-in" on vaccines and "all-out" against Ivermectin. Notice the remarkable similarity of the United Kingdom COVID graph when compared with Kerala's.
236   Patrick   ignore (1)   2021 Sep 14, 10:55pm     ↓ dislike (0)   quote   flag      

https://osf.io/preprints/socarxiv/r93g4/


Ivermectin and the odds of hospitalization due to COVID-19: evidence from a quasi-experimental analysis based on a public intervention in Mexico City

José Merinoi (i Digital Agency for Public Innovation, Mexico City)Victor Hugo Borja ii (ii, Mexican Social Security Institute)Oliva López, José Alfredo Ochoa iii (iii, Ministry of Health, Mexico City)Eduardo Clark, Lila Petersen, Saul Caballero iv (iv Digital Agency for Public Innovation, Mexico City)

Code: https://github.com/nasaul/paper_ivermectinaData:https://docs.google.com/spreadsheets/d/1VtXKW1IuCm4qRowlotXnTWZlhLoQYYmEsZp7ERUIeAQSummaryObjectiveTo measure the effect of Mexico City’s population-level intervention –an ivermectin-based Medical Kit––in hospitalizations during the COVID-19 pandemic.

Methods

A quasi-experimental research design with a Coarsened Exact Matching method using administrative data from hospitals and phone-call monitoring. We estimated logistic-regression models with matched observations adjusting by age, sex, COVID severity, and comorbidities. For robustness checks separated the effect of the kit from phone medical monitoring; changed the comparison period; and subsetted the sample by hospitalization occupancy,

Results

We found a significant reduction in hospitalizations among patients who received the ivermectin-based medical kit; the range of the effect is 52%-76% depending on model specification.ConclusionsThe study supports ivermectin-based interventions to assuage the effects of the COVID-19 pandemic on the health system.
237   Patrick   ignore (1)   2021 Sep 14, 10:58pm     ↓ dislike (0)   quote   flag      

http://www.pagina16.com.ar/ivermectina-brindan-resultados-parciales-de-monitoreo-en-el-uso-ampliado-en-pacientes-positivos/


Effectiveness
In the total population analyzed, a positive evolution of Covid-19 disease was observed, with an improvement in related symptoms of 48% and 77% at day 7 and day 14, respectively, after starting treatment. For most symptoms, improvement is observed within the first 48-72 hours after initiation of the Ivermectin protocol treatment regimen.


(translated)
238   Patrick   ignore (1)   2021 Sep 14, 11:00pm     ↓ dislike (0)   quote   flag      

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3765018


For the 24 states with early IVM treatment (and Lima), excess deaths dropped 59% (25%) at +30 days and 75% (25%) at +45 days after day of peak deaths. Case fatalities likewise dropped sharply in all states but Lima, yet six indices of Google-tracked community mobility rose over the same period. For nine states having mass distributions of IVM in a short timeframe through a national program, Mega-Operación Tayta (MOT), excess deaths at +30 days dropped by a population-weighted mean of 74%, each drop beginning within 11 day after MOT start. Extraneous causes of mortality reductions were ruled out. These sharp major reductions in COVID-19 mortality following IVM treatment thus occurred in each of Peru’s states, with such especially sharp reductions in close time conjunction with IVM treatments in each of the nine states of operation MOT. Its safety well established even at high doses, IVM is a compelling option for immediate, large scale national deployments as an interim measure and complement to pandemic control through vaccinations.


I suspect that ivermectin is far more effective than the vaxx, and with nearly zero side effects, unlike the vaxx which obviously kills with blood clots at first, and maybe ADE later.
239   Patrick   ignore (1)   2021 Sep 16, 3:57pm     ↓ dislike (0)   quote   flag      

https://rescue.substack.com/p/if-it-can-save-lives-the-world-needs?token=patrick.net

What motivates my writing about ivermectin is the enormous amount of misinformation and disinformation being heaped on this drug’s apparent life-saving potential in the fight against Covid. I want to be clear that I personally believe vaccines are the best resource available against this deadly virus, and I urge everyone to be vaccinated. That said, there is also an abundance of evidence that ivermectin: A) has virucidal properties; B) safely provides some protection against contracting Covid, and; C) appears to be efficacious in the treatment of Covid infection when used with other medicines.
240   Patrick   ignore (1)   2021 Sep 16, 3:57pm     ↓ dislike (0)   quote   flag      

https://rescue.substack.com/p/a-lifeline-from-buenos-aires?token=patrick.net

A Lifeline from Buenos Aires
Dr. Hector Carvallo's discovery that ivermectin prevents COVID-19 is saving thousands of lives and helping open regions and cities of the world to normal life. So why is he constantly attacked?
241   porkchopexpress   ignore (0)   2021 Sep 16, 4:40pm     ↓ dislike (0)   quote   flag      

The deep state is shitting their pants that Ivermectin is exploding across the globe. The genie is out of the bottle.
242   DhammaStep   ignore (0)   2021 Sep 16, 5:25pm     ↓ dislike (0)   quote   flag      

Started to feel sick today. Headache, sneezing, coughing, general fatigue, light and sound sensitivity. No loss of smell or taste though.

Even though I've had Covid, I immediately began the I-MASK+ protocol. Big thanks to all of you that pointed me in the right direction in obtaining the mectins. And Rin for the Quercetin Phytosome recommendation.

Now it's wait and see.
243   just_passing_through   ignore (8)   2021 Sep 16, 8:25pm     ↓ dislike (0)   quote   flag      

DhammaStep says
No loss of smell or taste though.


For me that was a week out after I was mostly recovering. I noticed when I was smoking some ribs. I couldn't smell the smoke. Thought I need to relight it until I SAW the smoke.
244   porkchopexpress   ignore (0)   2021 Sep 16, 10:34pm     ↓ dislike (0)   quote   flag      

If he had the 'vid already, he may not even lose taste and smell. It also could be the flu or a cold or something else.
245   Patrick   ignore (1)   2021 Sep 17, 9:42am     ↓ dislike (0)   quote   flag      

https://www.thegatewaypundit.com/2021/09/huge-uttar-pradesh-india-announces-state-covid-19-free-proving-effectiveness-deworming-drug-ivermectin/

Uttar Pradesh, India Announces State Is COVID-19 Free Proving the Effectiveness of “Deworming Drug” IVERMECTIN
246   Eric Holder   ignore (0)   2021 Sep 17, 11:46am     ↓ dislike (0)   quote   flag      

Robert Sproul says
For anyone interested, I finally found a source for ‘mectin that is easy to navigate and with easy payment options. Not the cheapest prices, but not gouging Westerners like some sources seem to be set up to do. Pay with PayPal, as I did, or credit card instead of cumbersome bank transfer boondoggles. I ordered a full compliment of FLCCC recommended early treatment medications. Free shipping over 200 bucks. Response was within hours and order fulfillment in 1 day. Now I wait for 20-30 days for delivery. I will report at that time.
https://www.genericcures.com


@Robert Sproul

Did you also get separate e-mail with request to transfer money via paypal to what looks like private person's account? Was it this guy?


247   mell   ignore (6)   2021 Sep 17, 12:02pm     ↓ dislike (0)   quote   flag      

@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.
248   Eric Holder   ignore (0)   2021 Sep 17, 12:02pm     ↓ dislike (0)   quote   flag      

mell says
@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.


Thanks!
249   DhammaStep   ignore (0)   2021 Sep 17, 12:04pm     ↓ dislike (0)   quote   flag      

DhammaStep says
Started to feel sick today. Headache, sneezing, coughing, general fatigue, light and sound sensitivity. No loss of smell or taste though.

Even though I've had Covid, I immediately began the I-MASK+ protocol. Big thanks to all of you that pointed me in the right direction in obtaining the mectins. And Rin for the Quercetin Phytosome recommendation.

Now it's wait and see.


Update: Feeling pretty good today. The mildest of headaches I don't even notice most of the time. All of the other symptoms are gone.

Dr. Pierre Kory and the FLCCC are courageous heroes as far as I'm concerned. They will be rewarded one way or another for their service to humanity, I am sure of it.
250   stereotomy   ignore (0)   2021 Sep 17, 12:10pm     ↓ dislike (0)   quote   flag      

mell says
@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.


Thanks for the info; I've had mine held up at JFK Customs since 9/1 (14 bidness days so far)

OTOH, my shipment from alldaypharmacy has already been delivered. Their stuff looks like doctors' pharma samples (1 pill in individual packaging as opposed to multiple pill blister packs). Manufacture date 6/21, so at least it's fresh.

EDIT: At least with PP, if customs confiscates I have recourse, unlike alldaypharmacy which is ACH.
251   Shaman   ignore (2)   2021 Sep 18, 3:38pm     ↓ dislike (0)   quote   flag      

New website for buying human versions of Ivermectin. India based. Bit more expensive but seems legit!
https://www.riverpharmacy.ca/drug/invermectin
252   WineHorror1   ignore (2)   2021 Sep 18, 3:41pm     ↓ dislike (0)   quote   flag      

mell says
@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

How did you find out it was held up in customs?
253   mell   ignore (6)   2021 Sep 18, 4:19pm     ↓ dislike (0)   quote   flag      

WineHorror1 says
mell says
@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

How did you find out it was help up in customs?


The company sends you a tracking number and website where you can track the package.
254   mell   ignore (6)   2021 Sep 18, 4:22pm     ↓ dislike (0)   quote   flag      

stereotomy says
mell says
@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.


Thanks for the info; I've had mine held up at JFK Customs since 9/1 (14 bidness days so far)

OTOH, my shipment from alldaypharmacy has already been delivered. Their stuff looks like doctors' pharma samples (1 pill in individual packaging as opposed to multiple pill blister packs). Manufacture date 6/21, so at least it's fresh.

EDIT: At least with PP, if customs confiscates I have recourse, unlike alldaypharmacy which is ACH.


Yep I would have charged back my payment if it hadn't arrived, no matter the reason. They have a fat margin so they can eat a few charge backs. I'd assume the total production cost of a $300 order is no more than $20-$30. And that's probably still way too high cause they produce high volume.
255   Patrick   ignore (1)   2021 Sep 19, 2:51pm     ↓ dislike (0)   quote   flag      

https://www.redvoicemedia.com/2021/09/india-state-that-pushed-ivermectin-now-free-of-active-covid-19-cases/


India State That Pushed Ivermectin Now Free of Active COVID-19 Cases
Ivermectin for the win?
256   Blue   ignore (0)   2021 Sep 19, 4:56pm     ↓ dislike (0)   quote   flag      

Patrick says
https://www.redvoicemedia.com/2021/09/india-state-that-pushed-ivermectin-now-free-of-active-covid-19-cases/


India State That Pushed Ivermectin Now Free of Active COVID-19 Cases
Ivermectin for the win?


Its interesting that this is the largest state turned to right wing party during few years back. At the same time there is another state (Kerala - politically far left) with highest level of vaccine rates experiencing highest number of daily cases.
At personal level, I do hear people sense the horror show if they get in to hospitals, instead take Ivermectin when they experience any symptoms.
257   Patrick   ignore (1)   2021 Sep 19, 5:04pm     ↓ dislike (0)   quote   flag      

@Blue That is indeed interesting.

The same basic dynamics are probably at work. A righteous and violently intolerant left claims to be open-minded, peaceful and tolerant.

They are typically the managerial and professional class which depends on suppressing critical thinking to keep their own positions. Too many questions = fired.

The poorer people, with a better grasp of reality and no need to lie to themselves or others to keep their jobs, if they even have jobs, correctly sees the jab as a threat to their lives and to their families. It's obvious to them, because they deal directly with corruption all the time and can easily recognize it.

I'm afraid that a lot of naive leftists are going to die directly due to their inability to recognize corruption.
258   WineHorror1   ignore (2)   2021 Sep 19, 5:11pm     ↓ dislike (0)   quote   flag      

Patrick says
I'm afraid that a lot of naive leftists are going to die directly due to their inability to recognize corruption.

I've got a long way to go to believe the overall death rate will be noticeably higher this winter.

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