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Ivermectin


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2021 May 9, 10:24pm   17,388 views  497 comments

by Patrick   ➕follow (49)   💰tip ($0.87 in tips)  

https://sebastianrushworth.com/2021/05/09/update-on-ivermectin-for-covid-19/

Back in January I wrote an article about four randomized controlled trials of ivermectin as a treatment for covid-19 that had at that time released their results to the public. Each of those four trials had promising results, but each was also too small individually to show any meaningful impact on the hard outcomes we really care about, like death. When I meta-analyzed them together however, the results suddenly appeared very impressive. Here’s what that meta-analysis looked like:



It showed a massive 78% reduction in mortality in patients treated with covid-19. Mortality is the hardest of hard end points, which means it’s the hardest for researchers to manipulate and therefore the least open to bias. Either someone’s dead, or they’re alive. End of story.

You would have thought that this strong overall signal of benefit in the midst of a pandemic would have mobilized the powers that be to arrange multiple large randomized trials to confirm these results as quickly as possible, and that the major medical journals would be falling over each other to be the first to publish these studies.

That hasn’t happened.

Rather the opposite, in fact. South Africa has even gone so far as to ban doctors from using ivermectin on covid-19 patients. And as far as I can tell, most of the discussion about ivermectin in mainstream media (and in the medical press) has centred not around its relative merits, but more around how its proponents are clearly deluded tin foil hat wearing crazies who are using social media to manipulate the masses.

In spite of this, trial results have continued to appear. That means we should now be able to conclude with even greater certainty whether or not ivermectin is effective against covid-19. Since there are so many of these trials popping up now, I’ve decided to limit the discussion here only to the ones I’ve been able to find that had at least 150 participants, and that compared ivermectin to placebo (although I’ll add even the smaller trials I’ve found in to the updated meta-analysis at the end).

As before, it appears that rich western countries have very little interest in studying ivermectin as a treatment for covid. The three new trials that had at least 150 participants and compared ivermectin with placebo were conducted in Colombia, Iran, and Argentina. We’ll go through each in turn. ...

What we see is a 62% reduction in the relative risk of dying among covid patients treated with ivermectin. That would mean that ivermectin prevents roughly three out of five covid deaths. The reduction is statistically significant (p-value 0,004). In other words, the weight of evidence supporting ivermectin continues to pile up. It is now far stronger than the evidence that led to widespred use of remdesivir earlier in the pandemic, and the effect is much larger and more important (remdesivir was only ever shown to marginally decrease length of hospital stay, it was never shown to have any effect on risk of dying).

I understand why pharmaceutical companies don’t like ivermectin. It’s a cheap generic drug. Even Merck, the company that invented ivermectin, is doing it’s best to destroy the drug’s reputation at the moment. This can only be explained by the fact that Merck is currently developing two expensive new covid drugs, and doesn’t want an off-patent drug, which it can no longer make any profit from, competing with them.

The only reason I can think to understand why the broader medical establishment, however, is still so anti-ivermectin is that these studies have all been done outside the rich west. Apparently doctors and scientists outside North America and Western Europe can’t be trusted, unless they’re saying things that are in line with our pre-conceived notions.


And HCQ falls into that same bucket. Even worse - to admit HCQ works would be to admit Trump was right about something.

Liberals would rather that millions die than that Trump be allowed to be right about anything. They hate Trump more than they love their fellow humans.

Comments 1 - 40 of 497       Last »

1   Shaman   2021 May 10, 8:01am  

Patrick says
They hate Trump more than they love their fellow humans.


In all honesty, that’s a low low bar. True Leftists love nobody but themselves and love nothing but power.
2   FarmersWon   2021 May 13, 1:01pm  

https://twitter.com/knapproductions/status/1392927268201275399
Just wondering if the WHO and world leaders have really got the public health as interest, or are they lining their pockets with money. I see the India covid cases have started to fall, first time in 2months. Why? Because they are taking Ivermectin:
4   Onvacation   2021 May 31, 2:32pm  

Dr. Pierre Kory on ivermectin for early covid treatment!


original link
/
From six months ago but still relevant.
5   Onvacation   2021 May 31, 2:45pm  

WE did not need an experimental biologic agent to fight this chimera. Ivermectin stops it dead in it's tracks.

The question is, why did THEY need it?
6   Patrick   2021 May 31, 4:58pm  

They needed the "vaccine" to gain profit and power.

There is nothing more to it.
7   Patrick   2021 Jun 5, 4:41pm  

https://www.medrxiv.org/content/10.1101/2021.05.31.21258081v1

Favorable outcome on viral load and culture viability using Ivermectin in early treatment of non-hospitalized patients with mild COVID-19 – A double-blind, randomized placebo-controlled trial
View ORCID ProfileAsaf Biber, Michal Mandelboim, Geva Harmelin, Dana Lev, Li Ram, Amit Shaham, Ital Nemet, Limor Kliker, Oran Erster, Eli Schwartz
doi: https://doi.org/10.1101/2021.05.31.21258081
This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.
AbstractFull TextInfo/HistoryMetrics Preview PDF
Abstract
Background Ivermectin, an anti-parasitic agent, also has anti-viral properties. Our aim was to assess whether ivermectin can shorten the viral shedding in patients at an early-stage of COVID-19 infection.

Methods The double-blinded trial compared patients receiving ivermectin 0·2 mg/kg for 3 days vs. placebo in non-hospitalized COVID-19 patients. RT-PCR from a nasopharyngeal swab was obtained at recruitment and then every two days. Primary endpoint was reduction of viral-load on the 6th day (third day after termination of treatment) as reflected by Ct level>30 (non-infectious level). The primary outcome was supported by determination of viral culture viability.

Results Eighty-nine patients were eligible (47 in ivermectin and 42 in placebo arm). Their median age was 35 years. Females accounted for 21·6%, and 16·8% were asymptomatic at recruitment. Median time from symptom onset was 4 days. There were no statistical differences in these parameters between the two groups.

On day 6, 34 out of 47 (72%) patients in the ivermectin arm reached the endpoint, compared to 21/ 42 (50%) in the placebo arm (OR 2·62; 95% CI: 1·09-6·31). In a multivariable logistic-regression model, the odds of a negative test at day 6 was 2.62 time higher in the ivermectin group (95% CI: 1·06–6·45). Cultures at days 2 to 6 were positive in 3/23 (13·0%) of ivermectin samples vs. 14/29 (48·2%) in the placebo group (p=0·008).

Conclusions There were significantly lower viral loads and viable cultures in the ivermectin group, which could lead to shortening isolation time in these patients.


Fauci suppressed not only HCQ but also Ivermectin.

Fauci is a mass murderer.
8   Blue   2021 Jun 5, 5:56pm  

A month back, a friend of mine back in India got Covid, 25 days after his first jab just before second one due and recovered fully in 10 days. He was able to convince the family to admit in hospital only if the oxygen level drops to significant low level. It was a stressful situation to the entire family.
He used Ivermectin (along with a second name I forgot) suggested by his doctor over the phone, instead of going to hospital after he heard lot of victims who are admitted got all sort of medications from nursing staff where doctors are absent in many cases! Medications include heavy doses of steroids, antibiotics etc, I suspect many cannot handle all these medications in a short period of the time and dies. Yet hospital charges exorbitant amount of money from their victims. In some cases they refuse to return dead body unless pay the bill in full. What a sad situation for those victim families. Still not too many are realizing the true picture of the medical and pharma industries.
9   richwicks   2021 Jun 5, 6:01pm  

Patrick says
They needed the "vaccine" to gain profit and power.

There is nothing more to it.


I don't think profit is an incentive anymore. It's only power.

The Federal Reserve can create as much money as they goddamned please.
10   mell   2021 Jun 5, 6:10pm  

richwicks says
Patrick says
They needed the "vaccine" to gain profit and power.

There is nothing more to it.


I don't think profit is an incentive anymore. It's only power.

The Federal Reserve can create as much money as they goddamned please.


Not without it eventually becoming worthless. Look at the dollar. They can print a lot to keep inflating their assets and not care about inflation for the common people, but they do have limits. Most of the wealth is created by creating demand artificially or coercion. The covid vaccines are a perfect example.
11   Onvacation   2021 Jun 5, 6:24pm  

richwicks says
The Federal Reserve can create as much money as they goddamned please.

And they know their days are numbered.
Fiat money only has value until it doesn't.
12   richwicks   2021 Jun 5, 6:47pm  

Onvacation says
richwicks says
The Federal Reserve can create as much money as they goddamned please.

And they know their days are numbered.
Fiat money only has value until it doesn't.


How many people own their car, their home, etc - outright?

The end of this is going to be a mass confiscation of physical wealth.
13   AmericanKulak   2021 Jun 5, 9:35pm  

richwicks says
I don't think profit is an incentive anymore. It's only power.


Yup. This is a great answer to "But if we regulate Twitter..." Twitter I think rarely makes a profit. WaPo also. They are "Loss Leaders" whose costs are paid to push a certain line, rather than traditional profit-seeking entities. This theory explains a lot of things they do that are counter productive, such as endorsing positions on CULTURAL issues that 2/3rd of Americans disagree with - including a solid majority of youth 18-29. So that throws the "Appeal to youth because future customers".

On a side note, I wonder if there is any research comparing the LOSS of long term customers turned off by BLM/LGBTQ+ vs. new customers onboarding. It certainly isn't appearing in current viewership, which is collapsing by double digits YoY.

ESPN, NBA, etc. have to be smoking crack not to see that the loss of long time viewership isn't offset by onboarding youths. IF they were profit maximizers, they wouldn't be pursuing the strategy they are, as today's 50-something sports fans are tomorrow's 70-something sports fans.
14   Patrick   2021 Jun 5, 10:51pm  

MisdemeanorRebellionNoCoupForYou says
Twitter I think rarely makes a profit. WaPo also. They are "Loss Leaders" whose costs are paid to push a certain line, rather than traditional profit-seeking entities.


This is the only rational explanation for their continuous alienation of large segments of the population.
16   Patrick   2021 Jun 9, 1:07pm  

https://vitamindwiki.com/High-altitude+Cusco%2C+Peru+has+far+lower+rate+of+COVID-19+than+others+%28high+UVB+and+Vitamin+D%29+-+June+2020


Many of the COVID-19 infections are in tourists (who have not gotten lots of UVB), not locals

"....Cusco, 6.7 % of men are obese, compared to Lima, where 24.4 % are."


Maybe Ivermectin just isn't enough to save you if you're obese.
17   Patrick   2021 Jul 24, 3:19pm  

https://www.theepochtimes.com/mkt_breakingnews/doctors-raise-awareness-on-ivermectin-as-treatment-for-covid-19-to-help-end-the-pandemic_3916366.html?utm_source=patrick.net&utm_medium=patrick.net&utm_campaign=patrick.net

Doctors Raise Awareness on Ivermectin Treatment for COVID-19
BY MEILING LEE July 24, 2021

In an effort to help end the pandemic, an international coalition of medical experts is holding worldwide events Saturday to raise awareness about the effectiveness of ivermectin as a treatment for COVID-19.
18   Ceffer   2021 Jul 24, 3:28pm  

You can buy apple flavored horse ivermectin in syringes on Amazon. Just adjust the dose for your weight compared to horse weight, squeeze a little out of the syringe to get the proper dosage. Quercetin is also available non prescription.
19   richwicks   2021 Jul 24, 4:00pm  

Patrick says
They needed the "vaccine" to gain profit and power.

There is nothing more to it.


I can't believe it has anything to do with profit. The federal reserve can, and does, print as much money as they wish. The pharma companies, you KNOW they got a ton of the Covid bailout money. Don't know what the point of the vaccine actually was, but we can pontificate.
20   Baloo   2021 Jul 24, 4:05pm  

Hi, did you know today is World Ivermectin day? Some outstanding videos about Ivermectin on Trialsitenews today. https://trialsitenews.com/world-ivermectin-day-north-america-panel/
It's beyond criminal that this medicine is not being used in every hospital with a coof patient.
21   Patrick   2021 Aug 3, 9:22pm  

https://www.medrxiv.org/content/10.1101/2021.05.31.21258081v1


Favorable outcome on viral load and culture viability using Ivermectin in early treatment of non-hospitalized patients with mild COVID-19 – A double-blind, randomized placebo-controlled trial
22   Patrick   2021 Aug 3, 9:23pm  

https://www.jpost.com/health-science/israeli-scientist-says-covid-19-could-be-treated-for-under-1day-675612


Israeli scientist says COVID-19 could be treated for under $1/day
Double-blind study shows ivermectin reduces disease’s duration and infectiousness
23   Patrick   2021 Aug 4, 12:52am  

Twenty countries are using Ivermectin to treat Covid-19. They include Mexico, Guatemala, Argentina, Brazil, Bolivia, Slovakia, the Czech Republic, Portugal, Nigeria, and Egypt. In South Africa doctors are allowed to prescribe Ivermectin, but it is not being rolled out everywhere and in hospitals and clinics.

According to Jackie Stone, a doctor in Zimbabwe, since January – when Ivermectin began to be used – it has cut COVID hospital admissions and deaths over 70%.

“The death rate rose sharply in January and peaked on the 25th at 70 deaths per day. Official authorisation for the use of Ivermectin was granted on 26th January. Just one month later, on 26th February, the COVID death rate had fallen to zero”.


https://www.biznews.com/health/2021/07/29/ivermectin-treatment
24   Rin   2021 Aug 4, 8:38am  

Just a reminder, we never needed any Rx for Covid. The answer was at our local (or mail order) Vitamin store all along. Here's the study in Italy for Quercetin Phytosome

https://patrick.net/post/1340407/2021-08-01-i-guess-better-late-than-never-but-here

Rin says
When co-morbidities are removed from the study ...


27   Patrick   2021 Aug 12, 12:07pm  

https://today.duke.edu/2021/08/why-covid-19-therapies-are-needed-help-curb-pandemic

DURHAM, N.C. -- A new study led by the Duke Clinical Research Institute is looking at whether three existing medications would treat mild-to-moderate COVID-19 effectively. (More information on the study is available here.)

The three repurposed medications, already approved by the U.S. Food and Drug Administration for other uses, are:

Ivermectin, used to treat parasitic infections;
Fluticasone, an inhaled steroid commonly prescribed for asthma and chronic obstructive pulmonary disease; and
Fluvoxamine, a selective serotonin reuptake inhibitor (SSRI), often prescribed for depression.
On Tuesday, institute executive director Adrian Hernandez discussed the study with reporters in a virtual media briefing, where he touched on the need for COVID-19 therapies and making it easy for people across the country to take part in the study.

Watch the briefing on YouTube.

Here are excerpts:

TREATING MILD-TO-MODERATE COVID-19
A study led by the Duke Clinical Research Institute has expanded its testing platform to evaluate three repurposed medications in the search for effective, safe treatments for mild-to-moderate COVID-19. Repurposed medications are those already approved by the U.S. Food and Drug Administration for other indications.

READ MORE
On the importance of testing COVID therapies

“We are in another surge here and it’s important to get answers for people who have mild to moderate COVID-19. What has been set up is a platform that will allow people anywhere across the country to join together to get those answers.”

“As we see COVID-19 surge, how can we actually address those issues by understanding what drugs work the best way and the easiest way for people to take at home if they, unfortunately, get COVID-19. We’ll be able to evaluate a number of different drugs that have a proven safety track record.”

On why the clinical trial matters now

“We are all interested in making sure we protect and prevent people from getting COVID-19 through vaccination and other efforts, but there are going to be cases when people get COVID-19 either through breakthrough cases or because someone hasn’t been vaccinated.”

“We have new variants that have developed over the last several months and we need to understand what are the best treatments that will make people feel better, faster, and also prevent them from going to the hospital or having any other poor outcomes.”


This is a nightmare for Pfizer!

Effective treatments make the clot shot unnecessary.

On the other hand:


@QMichelle17
4h
Replying to @CCoxley @RWMaloneMD @alexandrosM
Why are we expecting effective and appropriate trials when we have read the Pfizer contracts? No treatment can be found.


https://twitter.com/CCoxley/status/1425822559996682240#m

I know it sounds insane that a contract stipulates that no treatment is permitted be found or used to cure people, but I think that's literally what the Pfizer contract says.
28   Patrick   2021 Aug 13, 6:54pm  

https://rumble.com/vkhvzz-my-dads-ivermectin-story.html

His primary care doctor and his urgent care doctor both refused to prescribe Ivermectin. Once I found a doctor who would prescribe it, we had to get PERMISSION from the pharmacists to fill it. Then, this decades-old generic drug cost $120 (prices have gone up since then), when a comparable dose for my horses would cost less than $10. Here is the story.
29   Ceffer   2021 Aug 13, 6:59pm  

My first dose of horse ivermectin (I took it when healthy) did not seem to bother me at all that I can determine. That means we are compatible.
30   GNL   2021 Aug 13, 7:57pm  

I mentioned that both of my 83 year old parents tested positive for Covid. They have no breathing problems but complain of being terribly tired. Dad did go to Urgent Care at Kaiser last night. He was there for 17 hours and they sent him home with blood thinners because they are concerned he may have some blood clots (no, he did not take the clot shot). He took 2 doses of horse Ivermectin this past Saturday (a week ago). I do not know if it helped him or not. Mom took 2 doses of HCQ and no more. She took these last Saturday and Sunday. The hospital has offered both of my parents an infusion of antibiotics to combat Covid.

I believe this is what they have been offered...https://www.wral.com/coronavirus/unc-health-to-expand-use-of-antibody-treatment-to-prevent-covid-19-hospitalization/19819347/
31   porkchopexpress   2021 Aug 14, 8:50am  

WineHorror1 says
Mom took 2 doses of HCQ and no more
She needs to take zinc with HCQ since HCQ is the vehicle to get zinc into the cells to kill the virus.
32   GNL   2021 Aug 14, 10:25am  

porkchopexpress says
WineHorror1 says
Mom took 2 doses of HCQ and no more
She needs to take zinc with HCQ since HCQ is the vehicle to get zinc into the cells to kill the virus.

My sister and I put both of them on a daily regimen of Quercetin, D3, C and Zinc also. There are 5 of us kids and we are not all on the same page. My parents live with my sister and she is, I would say, in charge although she would not say that. I gave what I had to the cause (Ivermectin and HCQ) and voiced my opinion. We shall see what happens. So far, so good. They are mostly tired. Dad had a fever and went to Urgent care yesterday. He is now home and was given a blood thinner in case he has blood clots (no, they did not take the clot shot).
33   just_passing_through   2021 Aug 14, 1:21pm  

WineHorror1 says
I believe this is what they have been offered..


Antibodies are pretty safe as far as I know. For example that's what lots of cancer drugs are: antibodies matched with the cancer to guide the immune system to go in for the kill.

As opposed to chemotherapy which is basically just poison that one hopes kills the weaker cancer cells more than the normal cells.
34   GNL   2021 Aug 14, 3:21pm  

just_passing_through says
WineHorror1 says
I believe this is what they have been offered..


Antibodies are pretty safe as far as I know. For example that's what lots of cancer drugs are: antibodies matched with the cancer to guide the immune system to go in for the kill.

As opposed to chemotherapy which is basically just poison that one hopes kills the weaker cancer cells more than the normal cells.

Doesn't it sound like the vax delivered in a different way?
35   Patrick   2021 Aug 14, 3:39pm  

No injections at all for me thanks, not until Fauci has been tried for mass murder at least.

Equal opportunity.
36   just_passing_through   2021 Aug 14, 6:55pm  

Nope, totally different thing. Read up on humanized monoclonal antibodies if you're interested in the tech. It's not mRNA, spike protein or any of that crap.

They gave this to Trump when he had the coof.

It's expensive as all hell.
37   Patrick   2021 Aug 14, 6:58pm  

What I'm saying is that I no longer trust any injections.

Our criminal "public health" officials may decide to put the clot-shot under a different label, "for you own good" you know.

Clearly anyone who trusts "public health" officials at this point is naive to a life-threatening degree
38   PeopleUnited   2021 Aug 14, 7:21pm  

just_passing_through says
Nope, totally different thing. Read up on humanized monoclonal antibodies if you're interested in the tech. It's not mRNA, spike protein or any of that crap.

They gave this to Trump when he had the coof.

It's expensive as all hell.


Here is one example. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125377s096lbl.pdf
And a government approved fact sheet about monoclonal antibodies.

It is true they are expensive. They are also not without risk and thus we would only give them to those who have a serious illness. Trump did get them (not the kind cited above but an experimental formulation for treating his Wuhan flu), and promised that everyone who needed them would also get them. But obviously that did not happen. Sometimes I think Trump has no idea what he is saying, we probably don’t have the capacity to create enough monoclonal antibodies to treat everyone with the coof. The good news is that your chances of a bad outcome if infected are small.

There are protocols online for treatment based on stage of infection/severity of disease.
Scroll down to the middle of the page for the charts.
https://www.survivalistboards.com/threads/treating-covid-with-ivermectin.956864/page-38#post-20915284
Here is another reference. https://covid19criticalcare.com/covid-19-protocols/i-mask-plus-protocol/

This is not medical advice, just sharing some sources of info for those who are interested in seeing what others have published.
39   GNL   2021 Aug 14, 9:13pm  

Got to tell ya, I do not know what to believe. Too much information. Too much disagreement between every source. Too many lies and too much censorship.
40   Patrick   2021 Aug 14, 11:39pm  



So will they remove the emergency authorization for the jab now that there is a proven effective alternative treatment?

Any bets?

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