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Ivermectin


               
2021 May 9, 10:24pm   93,371 views  696 comments

by Patrick   follow (60)  

https://sebastianrushworth.com/2021/05/09/update-on-ivermectin-for-covid-19/

Back in January I wrote an article about four randomized controlled trials of ivermectin as a treatment for covid-19 that had at that time released their results to the public. Each of those four trials had promising results, but each was also too small individually to show any meaningful impact on the hard outcomes we really care about, like death. When I meta-analyzed them together however, the results suddenly appeared very impressive. Here’s what that meta-analysis looked like:



It showed a massive 78% reduction in mortality in patients treated with covid-19. Mortality is the hardest of hard end points, which means it’s the hardest for researchers to manipulate and therefore the least open to bias. Either someone’s dead, or they’re alive. End of story.

You would have thought that this strong overall signal of benefit in the midst of a pandemic would have mobilized the powers that be to arrange multiple large randomized trials to confirm these results as quickly as possible, and that the major medical journals would be falling over each other to be the first to publish these studies.

That hasn’t happened.

Rather the opposite, in fact. South Africa has even gone so far as to ban doctors from using ivermectin on covid-19 patients. And as far as I can tell, most of the discussion about ivermectin in mainstream media (and in the medical press) has centred not around its relative merits, but more around how its proponents are clearly deluded tin foil hat wearing crazies who are using social media to manipulate the masses.

In spite of this, trial results have continued to appear. That means we should now be able to conclude with even greater certainty whether or not ivermectin is effective against covid-19. Since there are so many of these trials popping up now, I’ve decided to limit the discussion here only to the ones I’ve been able to find that had at least 150 participants, and that compared ivermectin to placebo (although I’ll add even the smaller trials I’ve found in to the updated meta-analysis at the end).

As before, it appears that rich western countries have very little interest in studying ivermectin as a treatment for covid. The three new trials that had at least 150 participants and compared ivermectin with placebo were conducted in Colombia, Iran, and Argentina. We’ll go through each in turn. ...

What we see is a 62% reduction in the relative risk of dying among covid patients treated with ivermectin. That would mean that ivermectin prevents roughly three out of five covid deaths. The reduction is statistically significant (p-value 0,004). In other words, the weight of evidence supporting ivermectin continues to pile up. It is now far stronger than the evidence that led to widespred use of remdesivir earlier in the pandemic, and the effect is much larger and more important (remdesivir was only ever shown to marginally decrease length of hospital stay, it was never shown to have any effect on risk of dying).

I understand why pharmaceutical companies don’t like ivermectin. It’s a cheap generic drug. Even Merck, the company that invented ivermectin, is doing it’s best to destroy the drug’s reputation at the moment. This can only be explained by the fact that Merck is currently developing two expensive new covid drugs, and doesn’t want an off-patent drug, which it can no longer make any profit from, competing with them.

The only reason I can think to understand why the broader medical establishment, however, is still so anti-ivermectin is that these studies have all been done outside the rich west. Apparently doctors and scientists outside North America and Western Europe can’t be trusted, unless they’re saying things that are in line with our pre-conceived notions.


And HCQ falls into that same bucket. Even worse - to admit HCQ works would be to admit Trump was right about something.

Liberals would rather that millions die than that Trump be allowed to be right about anything. They hate Trump more than they love their fellow humans.

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657   stereotomy   2025 Mar 28, 7:00pm  

Just hit up alldaychemist. Although, I don't know how the tariffs and de minimus shipping changes will affect things. I loaded up right before TSHTF.
658   Maga_Chaos_Monkey   2025 Mar 29, 11:54am  

allfamilypharmacy worked out well, with refills. Took about a week to arrive but you can pay extra for overnight.

I tried Redbox Rx too and they also worked out well.

Probably more expensive but no concern of shipping from outside of the US.

This basically:

stereotomy says

All Family is much more expensive, but you don't have to worry about Customs inspections, and you get the fig leaf of a doctor's prescription.
661   Patrick   2025 Apr 17, 12:17pm  

https://www.theepochtimes.com/us/idaho-governor-signs-bill-for-ivermectin-to-be-sold-over-the-counter-5842316?src_src=Bright&src_cmp=bright-2025-04-17


Idaho Governor Signs Bill for Ivermectin to Be Sold Over the Counter

The measure, which the state Legislature passed earlier this year, went into law immediately on April 14.

Idaho has become the latest of a handful of states to legalize over-the-counter sales of the anti-parasite drug ivermectin following the COVID-19 pandemic.

Idaho Gov. Brad Little, a Republican, did not offer any comments on the bill, which was among many measures he signed on April 14. The bill had been passed with little resistance in the Idaho Legislature and took effect immediately.

In March, Arkansas Gov. Sarah Huckabee Sanders signed a bill legalizing over-the-counter sales of the drug, as did Tennessee Gov. Bill Lee in 2022.


So far, I have not found any legal US pharmacy that will ship ivermectin to California.
662   stereotomy   2025 Apr 17, 1:54pm  

Patrick says

So far, I have not found any legal US pharmacy that will ship ivermectin to California.

If you order form AlldayChemist and the order is confiscated by customs, there's no criminal or civil penalty other than forfeiture of the meds. They'll resend, and if confiscated again they'll refund your money.

I wouldn't buy much more than your family could reasonably use in several months. Massive orders are usually prima facie evidence of intent to distribute ("Dallas Buyer's Club") and should be avoided.
663   Patrick   2025 Apr 22, 2:13pm  

https://www.thefocalpoints.com/p/new-study-ivermectin-shows-striking


Largest review to date of ivermectin use in cancer patients finds no safety concerns, promising anecdotal reports, and strong preclinical evidence of tumor suppression.
664   stereotomy   2025 Apr 22, 2:43pm  

Ivermectin is the bomb. Artemisin might be just as good or better - @Rin recommended it.

That plus fenbendazole or its human prescription equivalents, should protect you from anything other than libtard homicidal violence.
666   Maga_Chaos_Monkey   2025 Apr 26, 10:40am  

stereotomy says

fenbendazole


I use that stuff to treat flukes on fish I purchase during their quarantine for my reef tank.
667   DemoralizerOfPanicans   2025 Apr 26, 11:48am  

It's IMPOSSIBLE that humans in China and Europe were using wormwood on themselves and domestic animals as a parasite and symptom cure (Artemisia)
They didn't have THE SCIENCE (tm).
However people did discover that barley seeds could be fermented in water by accident.
668   Maga_Chaos_Monkey   2025 Apr 26, 12:51pm  

Citric acid powder is another thing I use on my reef tank - to clean components I don't want to clean with harsher vinegar. It's what they sprinkle on sour patch kids candy to give that sour taste.

I've been growing a miracle berry bush now for almost 2 years and picked my 1st miracle berry last Wednesday. It contains miraculin which binds to sweet receptors basically turning them off.

However, they react to acids and 'bend' the sweet receptors causing them to explode in sweet flavor. So I had a bunch of stuff I'd never eat alone all lined up: lemon slices, kiwi slices, sauerkraut etc.

OMFG, I ate the whole lemon and it tasted like lemon candy! The kiwis and some other sour fruit were superb as well. I was surprised the sauerkraut didn't really taste any better. Maybe a bit.

It doesn't effect the flavor of non-sweet things either, like the beer I was drinking with it. Lasted about 30mins after I chewed the berry and swished it around in my mouth for a few mins.

I tested it in intervals 10mins, then about every 5 mins until things started tasting like shit again.

After that 1st berry the plant is blooming like crazy so I'm going to have a LOT of these soon. I'd truly wished it would have made sauerkraut taste better because I pop a table spoon of that with dinner and wash it down quickly near daily for the natural pre and pro biotics.

You can easily buy it freeze dried. No need to grow it like I am. Some people throw miracle berry parties haha. Obviously I'm not going to keep eating lemons like candy that has to be terrible for the teeth.

Was fun though!
669   Maga_Chaos_Monkey   2025 Apr 26, 12:56pm  

Ivermectin is supposed to treat scabies but the scabies are becoming drug resistant for anyone looking to use it for that, maybe try Benzyl Benzoate instead but you can't get that in the US anymore - unless you buy the horse emulsion which is identical to what docs used to prescribe in the US for people.

Resistant to permethrin too which is a problem with all of the illegal aliens showing up here.

They've been put up in hotels for free (even the very nice ones) and you can catch that shit from the sheets.

Australia still prescribes Benzyl Benzoate for scabies.
670   stereotomy   2025 Apr 26, 5:13pm  

Maga_Chaos_Monkey says

I've been growing a miracle berry bush now for almost 2 years and picked my 1st miracle berry last Wednesday. It contains miraculin which binds to sweet receptors basically turning them off.

What is this stuff? Do tell.
671   stereotomy   2025 Apr 26, 5:15pm  

FYI Ivermectin is getting tougher to get - probably supply chain disruptions.
672   Maga_Chaos_Monkey   2025 Apr 26, 7:39pm  

stereotomy says


What is this stuff? Do tell.


https://mberry.us/products/mberry-freeze-dried-miracle-berries

I hear the vinegar claim they made (watched someone do it on utube) is BS. But the lemon I ate definitely tasted like yummy candy. Way better than candy like lemon drops in fact.

I don't know if freeze dried is as good as a fresh berry like I ate.

I think next time I'm going to eat a little bit of my citric acid fish tank pump cleaning powder.
673   DemoralizerOfPanicans   2025 Apr 26, 10:09pm  

Glad the berry is working out for ya.

I eat like half a pint of sauerkraut with every sausage or hotdog, with a good tablespoon or two of mustard to boot, and put ONLY balsamic vinegar in my salad (sometimes with a little mustard, too).

Pickles too and sometimes a tablespoon of Pickle Juice in a cold cup of water for rehydration power. Better than sugary gatorade or expensive powdery concoctions. A shot of pickle juice before bed when you have muscle strains or cramps is better than ANY OTC and probably most Rx.

One big reason our health might be going to shit is because compared to earlier generations that had only limited/no refrigeration in the house, we eat a lot less fermented vegetables. Interestingly, ALL of the longest lived people - Japanese, Greek Islanders, Scandinavians - eat a ton of fermented foods.
674   DemoralizerOfPanicans   2025 Apr 26, 10:22pm  

Maga_Chaos_Monkey says

But the lemon I ate definitely tasted like yummy candy. Way better than candy like lemon drops in fact.

Awesome, reading about the history now.
675   HeadSet   2025 Apr 27, 7:45am  

AmericanKulak says

Pickles too and sometimes a tablespoon of Pickle Juice in a cold cup of water for rehydration power

I remember as a kid that pickled eggs and picked beets were common. Also, kids drank the pickle juice after the pickles were gone.
676   Maga_Chaos_Monkey   2025 Apr 27, 7:51am  

AmericanKulak says

Better than sugary gatorade or expensive powdery concoctions. A shot of pickle juice before bed when you have muscle strains or cramps is better than ANY OTC and probably most Rx.


I'm going to try that!
679   Patrick   2025 Jun 12, 11:29am  

It's criminal that ivermectin is not available over the counter in every state.

Is safer than aspirin.
682   HeadSet   2025 Jun 23, 2:47pm  

Patrick says





No irony here, with your comments on Canola Oil originally being an engine lubricant?
683   Patrick   2025 Jun 27, 2:29pm  

https://www.coffeeandcovid.com/p/civil-wars-friday-june-27-2025-c


No drug in history has been more unfairly targeted for reputational destruction than ivermectin. The FDA —before being slapped down by courts— ran a smirking negative public relations campaign against the medication, not in the science journals, but on social media. Its efforts were crowned with the infamous folksy tweet that finally broke the legal straw: “You are not a horse,” it said. “You are not a cow. Seriously, y’all. Stop it.”

Two years later, the courts forced the FDA to delete that tweet. Ironically —and tellingly— the FDA’s lawyers rode into court arguing the horse tweet was not medical advice. The judge gave that claim the old horse’s laugh. Seriously, y’all aren’t doctors.

Ivermectin is available over the counter in most of the third world, a fact glaringly conspic. by its a. from the Atlantic’s story. Apparently, in the government’s view, Americans are less trustworthy in making their own health decisions than sub-Saharan Africans and rural Indians. During the pandemic, India’s government tried to move ivermectin behind the counter, but gave it up as a lost cause after irate citizens grabbed pitchforks and began melting tar. ...

A growing group of states are flatly rejecting the scientific-medical establishment. States are using their legislative authority to claw back control over pharmaceutical access— bucking FDA orthodoxy and the entire pandemic-era narrative.

Most significantly, the rebellion isn’t found amongst hemp-clad mushroom circles or barefoot health-retreat crowds storming the Capitol with peace signs. It’s sober, straight-laced state legislators — churchgoers, Rotarians, small-town mayors turned senators — who now don’t trust the FDA even to regulate a generic anti-parasitic.
684   stereotomy   2025 Jun 30, 10:19pm  

Alldaychemist.com has a 10% off coupon good up to $30 (FIREWORKS10). It's probably good up until 7/3/25, and is good for multiple orders. They have ivermectin for $1 per 12 mg pill when you buy a box of 100.

Things I've found out from putting in multiple orders with ADC:

You can only order 1 of each SKU - this is to minimize customs red flags.

Order 3+ items for lowest shipping ($10 per order). 1 item is $20, 2 are $15.

If you pay by eCheck, you need to wait 24 hours between orders if doing multiple orders.

It takes anywhere from 2 weeks to over a month to get your stuff, depending on the customs ports.

They have a shipment guarantee if there's an interception and will reship. They're pretty careful though, so I've never had problems with them. I tried another place once and that got intercepted.
.
Customer service is good - one time I got an empty blister pack in a box of ivermectin. I sent them a photo and they refunded me more than the difference via Paypal. I had Paypal send me a check (fuck linking any bank account to Paypal), so the refund worked out even with the check processing fee.
688   stfu   2025 Jul 16, 4:27am  

I have an anecdotal story from a friend I talked to yesterday.

His Wife tested positive for Lyme disease a month or two ago. They are super red pilled so she refused the anti-biotics that is the normal treatment. My friend has a shit ton of Ivermectin - so they started treating her with this under supervision of their family physician (also red pilled surprisingly) and last week she tested negative for Lyme disease.

I don't know the dosages or duration but I thought it was worth sharing.
690   Patrick   2025 Aug 17, 11:40am  

https://publicacoes.cespu.pt/index.php/sl/article/view/305


Ivermectin decreases the expression of ALDH1 in ovarian cancer cell lines in combination with chemotherapy

Conclusions: High levels of ALDH1 are associated with chemoresistance. The low levels of ALDH1 found in ovarian cancer cells treated with Ivermectin plus carboplatin or paclitaxel reveal a more sensitive profile, which could be a promising alternative for ovarian cancer treatment.
691   Patrick   2025 Sep 15, 11:26am  

https://www.coffeeandcovid.com/p/accelerating-monday-september-15


Rounding out our New York Times review this morning, behold this astonishing headline: “What Ivermectin Can (and Can’t) Do.” I bet you never expected to see an ivermectin headline appear in the Times without a dire warning. Let the retconning begin. ("retroactive continuity" where the NYT pretends that they were telling the truth before when they were clearly lying as usual - Patrick)

The story began by carefully mocking claims the drug cures covid, don’t even think about that. But it explained in gruesome detail how well the Nobel-prize-winning drug kills intestinal worms. Then the story finally got around to what it really wanted to sneer at: people who claim ivermectin cured their cancer. The Times contemptuously smirked:

A wealth of research has shown the drug does not treat Covid. And
there is not evidence to support people taking ivermectin to treat
cancer.

Got it, dummies? Y’all aren’t horses with parasite problems. Stop munching ivermectin pills for your skin cancer. “There is not evidence.” Get that through your thick, Cro-Magnon skulls. No evidence. None.

But wait. Um.

Many paragraphs later —in the same story— the Times said this:

Studies in human cells suggest that the drug may kill certain types
of cancer cells in a way that triggers the immune system, said Dr.
Peter P. Lee, chair of the department of immuno-oncology at
Beckman Research Institute of City of Hope in Duarte, Calif. In
mouse studies, Dr. Lee has seen that the drug, on its own, does not
shrink breast tumors. But it's possible that the drug may have
benefits for breast cancer when used alongside existing cancer
immunotherapy, he said. Researchers are studying a combination
of ivermectin and an investigational cancer drug in people with
breast cancer.
While some inaccurate social media posts claim that ivermectin
can treat cancer because tumors themselves are parasitic, the
promise of ivermectin for cancer has nothing to do with its anti-
parasitic effect, Dr. Lee said. Rather, it seems that the drug may be
able to modulate a signal involved with cancer growth.

In other words, studies, research trials, and doctors’ opinions all credibly suggest that ivermectin might help stop cancer. So … when the Times said there is not evidence for ivermectin as a cancer treatment, it meant there IS evidence. Reading the Times requires a certain amount of mental flexibility. Orwell would nod ruefully.

Should we line our parakeet’s cage with this contradictory story? Or should we perhaps recognize that the reporter managed to smuggle in the hopeful, heterodox information about ivermectin and cancer, while still regurgitating the party line about its uselessness? As a hopeless optimist, I choose the latter. I suspect the reporter is secretly convinced.
692   stereotomy   2025 Sep 15, 11:44am  

Alldaychemist is currently not shipping to the US until they figure out the new rules after the elimination of de minimus (<$800) customs and duty exclusions. I hope everyone backed up the truck before this.

Otherwise it's the horse paste for low-cost ivermectin in the meantime.
693   Patrick   2025 Sep 26, 11:08am  

https://www.coffeeandcovid.com/p/the-storm-begins-friday-september


On Tuesday, Republican State Representative Jeff Holcomb filed a bill (HB 29) to allow ivermectin to be legally purchased without a prescription. In other words, over the counter. It’s still early, and the bill is far from being approved. But I’ve learned from insiders that the lower the bill number, the better. (Long-shot bills unsupported by the party usually get numbers in triple digits.) ...

The left-leaning paper saw an apocalypse of peril approaching. Look out! Misinformation! “Despite the potential health risks,” FlaPol warned readers, “several states including Arkansas, Idaho, Louisiana, Tennessee and Texas have passed laws this year permitting over-the-counter sales of ivermectin.” Oh, no!

But on the other hand, Tylenol— by all means, eat them by the handfuls. Who cares what the FDA says?

The second Ivermectin story was even better. The Florida Pheonix ran another story about Florida and the anti-parasitic, headlined, “Ivermectin, from the Capitol to state-funded cancer research — it’s a thing in Florida.”

Let’s be honest. Thanks to chronic Trump Derangement, Ivermectin triggers liberals. Just hearing that word makes them fume and angrily clench their jaws until they crack their crowns. They fervently wish the Nobel-winning drug would just go away, or at least return to Africa or whatever uncredentialed hellhole it wriggled out of.

Covid was bad enough. But the idea of conservatives being allowed to treat their cancers with the inexpensive medicine makes liberals want to scream in futile rage.

So you can imagine how upset they were when, on Tuesday, Governor Ron DeSantis, First Lady Casey DeSantis, and Surgeon General Joe Ladapo held a press conference at the University of South Florida for World Cancer Research Day, and announced $60 million in new cancer research grants.

Everything was going fine until Casey said she expected some part of the new funding to be used for cancer research on ivermectin. “We should look at it,” Mrs. DeSantis said. “We should look at the benefits of it. We shouldn’t just speculate and guess,” she added innocently, seemingly unaware of how badly progressives would take that news.

For purposes of full disclosure, I personally know two people so far who’ve been diagnosed with late-stage cancers, took ivermectin in combination with other treatments (but not high levels of chemo and radiation), and both made a full recovery and are now cancer-free. ...

Liberals like the Phoenix have shot far past admitting ivermectin-cancer studies exist. They could have stopped short at demanding a large-scale, peer-reviewed, “gold standard” double-blinded study. That would have been their best move. Large-scale studies on ivermectin and cancer were always unlikely, since pharma won’t fund them.

But instead, liberals have decided to simply refuse to concede even any possibility ivermectin might help. ...

You have to hand it to them. That level of disbelief takes work. Even a quick lawyer’s search turned up dozens of studies showing ivermectin’s promise for treating cancer.

I’ve cited others before, but here’s another new one, published this April in Medical Oncology:

https://pubmed.ncbi.nlm.nih.gov/40257544/
Antitumor potential of ivermectin against T-cell lymphoma-bearing hosts

“Ivermectin,” the researchers began, “has shown promising anticancer potential.” They continued, “Originally developed for veterinary and human use against parasitic infections, ivermectin demonstrated significant antitumor effects in our study against tumor cells.”

Over the last four years, other independent studies have found more remarkable results combining ivermectin with traditional chemotherapy or other repurposed drugs, like metformin (a diabetes drug) and tamoxifen (an estrogen antagonist).

You can show these studies to progressives, but what’s the point? They won’t listen. They’ll just sneer, gobble some Tylenol, and sarcastically ask, Doing your own research again? It’s kind of tragic.

“Generic medicines are often overlooked,” First Lady DeSantis said, “because they are off-patent and don’t necessarily promise big profits.” Florida’s 2025 budget allocated $218 million total for cancer, with $60 million carved out for nutrition and “the repurposing of generic drugs such as ivermectin for cancer treatment.”

As they say, talk is cheap. But Florida just did more than talk. It allocated $60 million for grants to study repurposed drugs in treating cancer. That is a tangible step toward Making America Healthy Again. So far as I can tell, this level of investment by any U.S. state in repurposed cancer drugs is a historic first.
694   stereotomy   2025 Sep 26, 11:21am  

Ivermectin is the shit. It inhibits everything. Even better, with another related drug, it fights cancer.

From Makis:


695   Patrick   2025 Oct 11, 9:59am  

https://www.coffeeandcovid.com/p/dizzying-dichotomies-saturday-october


Another ivermectin study is out, and like the long list of similar studies lately, it shows more cancer treatment potential. This one was published in July in ACS Biomaterials Science, titled, “Intranasal Delivery of Ivermectin Nanosystems as an Antitumor Agent: Focusing on Glioma Suppression.”

https://pubs.acs.org/doi/10.1021/acsbiomaterials.5c00642

In short, the study found low-dose ivermectin shrank brain tumors by a whopping 70% in rats. The treated rodents also had less dead tissue, less swelling, and fewer new blood vessels forming, which means the remaining tumors were less invasive and less aggressive.

The ivermectin was delivered using a nasal spray in a very fine (nanoscale) form, since oral ivermectin can’t cross the blood-brain barrier. The rats that got the treatment showed no negative side effects.

The serendipitous discovery of ivermectin is one of the most remarkable stories in medical science. In the 1970s, Japanese microbiologist Satoshi Ōmura set out to find new microorganisms that might produce useful medicines. He collected hundreds of soil samples from around Japan, including one from a golf course in Kawana, south of Tokyo.

In one of his golf-course soil samples, Ōmura’s team isolated a previously unknown bacterium that produced compounds found to be extraordinarily effective at killing parasitic worms. He sent it to a U.S. lab at Merck, which developed ivermectin: a safer and even more potent chemical derivative of the bacterial compound.

As you know, in 2015, Ōmura and Merck researcher Bill Campbell jointly received the Nobel Prize in Medicine for a cheap dirt drug that has saved millions from disease and blindness. If ivermectin’s cancer-fighting abilities bear out —and the studies and anecdotes keep mounting up— it will become the single most beneficial accidental discovery in human history.

Here’s a question to ponder: would ivermectin have broken out of the pharma wilderness absent its high-profile role during the pandemic as a cultural and political flashpoint? Without this extraordinary exposure, efforts to study ivermectin as a cancer agent would almost certainly have remained niche— buried in the literature amid hundreds of other “drug repurposing” efforts, lacking funding, conference time, or media coverage.

Ivermectin may wind up being the greatest covid miracle of all.
696   stereotomy   2025 Oct 17, 2:51pm  

alldaychemist is no longer shipping to the US because of the changes in de minimus rules for customs. They say they're figuring it out, but I'm not optimistic. I guess we'll have to take an annual pilgrimage to Mexico to get the goods - $5 a pill in the USA is bullshit.

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