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Regulatory and Safety Assessment of COVID-19 mRNA-LNP Genetic Vaccines in Japan: Evidence for Revocation of Approval and Market Withdrawal
Jun Ueda
Miki Gibo
Takayuki Kikuchi
Yuriko Hirai
Mariko Miyokawa
Isamu Shima
Shinichiro Kodama
Masanori Fukushima
08/26/2025
... Despite numerous reports of health injuries both domestically and internationally as of June 2025, the Japanese government has not conducted a nationwide health injury survey into these adverse health effects. These vaccines were approved without adequate non-clinical testing and long-term safety evaluation, and administration continued without sufficient disclosure of adverse events. This paper discusses in detail the scientific deficiencies in the regulatory review of genetic vaccines, inadequacies in post-marketing risk management, and issues concerning significant adverse drug reactions and potential DNA contamination in genetic vaccines. It is evident that genetic vaccines that received special approval for emergency by the Japanese government lack sufficient evidence of efficacy, and their potential risks to public health cannot be overlooked. A comparison with previous cases of pharmaceutical approval revocations indicates that revoking the approval and withdrawing genetic vaccines from the market is not only reasonable but also necessary.
The millions of molecules of MRNA entering the cell is creating biochemical havoc. It's disrupting protein metabolism, it's interfering with tumor suppressor genes. It had to be stopped interfering with tumor suppressor genes. In other words, it may be a risk factor for cancer. And I've been asked today to share this isn't just his opinion, many other doctors feel the same way. But one of Britain's most eminent oncologists, Professor (Dalgleish), said to me to share with you today, that he thinks it's highly likely that the COVID vaccines have been a factor, a significant factor in the cancer of members of the royal family.
“Fall-related mortality among older adults has been climbing sharply.”
And there it was. Seniors are not so much climbing sharply as they are toppling over faster than bowling pins in an earthquake. ...
The scholarly 2011 article mentioned no trend in increased fall rates. Nor did a CDC pamphlet from 2019. You’d think if there were a steadily increasing trend in fatal falls, either source would’ve said something. ...
Annoyingly, the one thing they won’t look at is the most likely cause: the jabs.
Irish racing in shock as top point-to-point jockey dies suddenly aged just 44
Mikey O’Connor, who had ridden 429 point-to-point winners during his career, collapsed and died while at his yard at the age of 44.

Popular liberal radio host and Democratic Party darling Lenard McKelvey, aka Charlamagne, has made a confession to his listeners about his thoughts on Covid “vaccines.”
Charlamagne shocked his audience after revealing that he has suffered ongoing chest pain since receiving the Covid “vaccine” and admitted he regrets taking the shot.
The exchange happened live on New York City’s Power 105.1 FM “The Breakfast Club” during the popular “Get It Off Your Chest” segment.
A caller, identified as James from North Carolina, phoned in to blast Health and Human Services Secretary Robert F. Kennedy Jr., calling him unfit to speak on public health. ...
Charlamagne, the show’s lead host and a longtime Democrat supporter, immediately pushed back. ...
Then Charlamagne dropped the bombshell.
“I ain’t going to lie. Every time I have chest pain now, I be like, ‘Man, I should have never got that damn Covid shot,’” he admitted.
“I had no cardiovascular issues until I got that goddamn Covid shot.”
Co-host DJ Envy also weighed in, blasting the government and corporations for forcing people into the jab.
“[They] kind of forced us to get the Covid shot. Right,” Envy said.
“We didn’t have an option if we wanted to continue to work, which sucks.”

".
Swedish Health Minister #ElisabethLann fainted during a press conference.
She collapsed along with the podium as she was being introduced to the post.
Local media reports that Lann's blood sugar dropped, but she was quickly revived.
The ultimate red flag: the very first person paraded out to take the COVID jab collapsed almost immediately. That moment alone should have shattered the narrative, yet media spun it as normal. Obvious warning ignored.
The ultimate red flag: the very first person paraded out to take the COVID jab collapsed almost immediately.
56% Suspect COVID-19 Vaccines Caused Deaths
Thursday, September 11, 2025
More than half of voters think COVID-19 vaccines may have killed many people, and back Health and Human Services (HHS) Secretary Robert F. Kennedy Jr.’s criticism of government health officials.
The latest Rasmussen Reports national telephone and online survey finds that 56% of Likely U.S. Voters consider it likely that side effects of COVID-19 vaccines have caused a significant number of unexplained deaths, including 32% who believe it’s Very Likely. Thirty-five percent (35% say it’s not likely there were significant deaths from COVID-19 vaccines, including 17% who think it’s Not At All Likely. These findings have changed little since September 2024.

Multisystem Endothelial Inflammation: A Key Driver of Adverse Events Following mRNA-Containing COVID-19 Vaccines
One widely discussed aspect of these vaccines is their uniquely broad spectrum and increased incidence of adverse events (AEs), collectively referred to as post-vaccination syndrome (PVS). ...
A prominent manifestation of PVS is multisystem inflammation, hypothesized to result from the systemic transfection of organ cells with genetic instructions for a toxin, the spike protein, delivered with lipid nanoparticles (LNPs). In this narrative review, we focus on endothelial cells in the microcirculatory networks of various organs as primary sites of transfection with mRNA-LNP and consequent PVS. We outline the anatomical variations in the microcirculation contributing to the individual variability of symptoms and examine the molecular and cellular responses to vaccine nanoparticle exposure at the endothelial cell level with a focus on the pathways of a sustained cascade of toxic and autoimmune processes.
The FDA reportedly confirmed during the sweeping review of “vaccine” safety data that many of those deaths were caused by Covid mRNA injections.
The federal agency linked the injections to the deaths of American children, marking a devastating blow to years of official claims that the so-called “vaccines” are “safe and effective.”
According to a bombshell report in The Washington Post, FDA officials plan to formally acknowledge 25 child deaths in the U.S. that were identified during the investigation as being directly caused by the shots.
Wall Street responded swiftly to the news.
Pfizer, BioNTech, and Moderna all saw shares plunge in Friday trading as investor confidence in the “safe and effective” narrative evaporated.
A Georgia golf sensation has collapsed and died unexpectedly, according to local officials and family members.
Seventeen-year-old Hadden Kelly was a junior at Dodge County High School.
He was “TPing” a yard while taking part in a homecoming prank with friends in his hometown on Monday morning when he suddenly collapsed, relatives said.
A friend discovered him unresponsive around 9:00 a.m.
One of the world’s leading data analysts has sounded the alarm, revealing that the insurance industry is now tracking up to 5,000 deaths every single week linked to the Covid mRNA “vaccines.”
The revelation comes from Edward Dowd, a former Wall Street executive and respected data expert, who disclosed the findings in a recent interview with the Commodity Culture podcast.
Dowd, who has been monitoring life insurance and disability trends since the rollout of the shots, warned that the number of “healthy young adults dropping dead” has skyrocketed at an unprecedented rate.
Injuries 10–15 Times Higher Than Before
According to Dowd, it’s not only deaths spiking but also devastating injuries.
“Injuries are 10–15 times higher” than pre-2021 levels, he explained.
Dowd said the hardest-hit demographic is people in their 30s, 40s, and 50s, age groups that previously had low mortality risk but are now appearing in excess death data across the insurance industry.
“30–50-year-olds are dropping dead,” Dowd said bluntly.
Equally disturbing, Dowd noted, is that families of victims and the injured are being silenced, not by law but by fear.
“The victims fear backlash or can’t accept they were misled,” he explained, adding that corporate media and Big Tech platforms are actively censoring reports of vaccine-linked injuries and deaths.
Suppression by Media and Tech
Dowd argues the scale of the crisis is being hidden in plain sight:
“The media and tech giants actively suppress these stories,” he warned.
The suppression campaign has allowed officials and pharmaceutical companies to continue pushing the narrative of “safe and effective,” even as insurance companies quietly pay out billions in claims tied to sudden deaths, disabilities, and long-term illnesses.
RNA – VACCINES: INTERIM RESULTS OF THEIR USE
Seliverstova Angelina Alekseevna, Makeev Oleg Germanovich
Department of Biology and Biotechnologies
Ural State Medical University
Yekaterinburg, Russia
Results. A correlation has been found between the increased incidence of cancer and the widespread use of COVID – 19 vaccinations.

Data from 8,407,849 individuals between 2021 and 2023 were obtained from the Korean National Health Insurance database. The participants were categorized into two groups based on their COVID-19 vaccination status. The risks for overall cancer were assessed using multivariable Cox proportional hazards models, and data were expressed as hazard ratios (HRs) and 95% confidence intervals (CIs). The HRs of thyroid (HR, 1.351; 95% CI, 1.206–1.514), gastric (HR, 1.335; 95% CI, 1.130–1.576), colorectal (HR, 1.283; 95% CI, 1.122–1.468), lung (HR, 1.533; 95% CI, 1.254–1.874), breast (HR, 1.197; 95% CI, 1.069–1.340), and prostate (HR, 1.687; 95% CI, 1.348–2.111) cancers significantly increased at 1 year post-vaccination. In terms of vaccine type, cDNA vaccines were associated with the increased risks of thyroid, gastric, colorectal, lung, and prostate cancers; mRNA vaccines were linked to the increased risks of thyroid, colorectal, lung, and breast cancers; and heterologous vaccination was related to the increased risks of thyroid and breast cancers. Given the observed associations between COVID-19 vaccination and cancer incidence by age, sex, and vaccine type, further research is needed to determine whether specific vaccination strategies may be optimal for populations in need of COVID-19 vaccination.
A world-renowned Swiss doctor has issued a chilling alert to the public, warning that Covid mRNA “vaccines” have triggered a “pandemic of severe illnesses and sudden, unexpected deaths.”
“This modified RNA [mRNA] genocide is the greatest medical crime in human history,” he declares.
“A humanitarian disaster of unprecedented proportions.”
He continued by warning about the push by the pharmaceutical industry to shift all “vaccinations” to use dangerous-but-profitable mRNA technology.
Binder raised the alarm in a video message to the world, shared on social media.
https://rumble.com/v6zmpye-top-doctor-sounds-alarm-covid-vaccines-triggered-sudden-unexpected-death-pa.html
25. Indeed, prior to the public’s Covid-19 vaccination beginning Spring 2021, Plaintiff
roughly estimated that CRMC’s third floor units averaged about four unborn baby deaths per year, or
one or two per month. Whatever the exact number, staff considered that “normal” or the baseline.
Plaintiff’s ability to estimate the number was limited to her personal observations, such as reviewing
her patient charts, conversations with patients and colleagues, and watching the boards that track
patients through the hospital units.
26. But beginning in Spring 2021 and thereafter, Plaintiff estimated CMC’s fetal demise
rate spiked to approximately 4 per week—an exponential increase (between 767% to 5,100%) from
pre-2021 levels according to her rough estimate. Lacking access to a full data set (i.e., CMC-wide
medical records), Plaintiff could only estimate from her limited observation. And yet her observation
was not isolated because Plaintiff and colleagues observed that the spike in unborn baby deaths
(whatever the exact number) caused a nightmarish time at the hospital. Plaintiff would come to work
at CRMC Fresno and there would often be a dead baby (even if not on that day, recently enough to
be discussed by staff as current). Management circulated an email to staff about this matter that was
so shocking it could not be ignored. See Exhibit A – Record High Dead Babies Email. Not only did
the increase in unborn baby deaths occur, but mothers suddenly (beginning March 2021 and
continuing thereafter during the Covid-19 vaccine distribution to pregnant women per hospital
policies) began having more frequent and more significant health problems (i.e., vascular, clotting,
hemorrhaging) that did not occur prior to Spring 2021 based on Plaintiff’s direct observations and
conversations with colleagues.
Yesterday, the UK Daily Mail made history by running a story headlined, “Covid jabs ‘might raise the risk of cancer’, contentious study claims.” Somehow the new peer-reviewed study survived the editorial gauntlet, presumably by careening over the highway bridge and racing up the stormwater drain or something. Anyway, it’s out now, disturbing Daily Mail readers who’ve just awakened from comas and only remember that the government promised that the jabs were the most studied and safest vaccines ever made since Washington pricked his soldiers with something gross that came off a cow.
The article began with a mandatory mention that the latest covid variant “Nimbus” is even more infectious than the previous six hundred variants, each more infectious than the last, having become so infectious now that Nimbus actually travels back in time and infects your great-great-grandfather long before you were born. So if you don’t get your shot, you’re literally killing great-great-grandpa.
But then came the devastating bombshell, in the form of a new, peer-reviewed Korean study of the health records of 8.4 million South Koreans.
https://biomarkerres.biomedcentral.com/articles/10.1186/s40364-025-00831-w
This news may shock you, but the researchers concluded that people who took the covid mRNA shots were significantly more likely to get loads of different kinds of cancers, making the shots equal opportunity killers that can qualify for various kinds of pro-social government grants.
Worse, the study only looked at the first year following the shots. So the real figures could be much, much worse.
As if to immunize itself from criticism about publishing “misinformation” that might make people “hesitate,” the article carefully quoted several sneering experts who dismissed the study, calling it ‘superficially alarming’ and warning that its conclusions were ‘hugely overblown.’ They didn’t provide any specifics, because they are experts and you’re not.
But the article also included the study’s more-than-superficially alarming chart showing rather actually-alarming dots and lines next to scary labels like: overall cancer, brain, thyroid, salivary, gastric, colorectal, lung, breast, and prostate— which are all things and places on the body where the last thing most people want is a strange new growth.
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