44
1

Funny picture thread


 invite response                
2011 Dec 9, 1:03am   1,310,308 views  9,648 comments

by zzyzzx   ➕follow (9)   💰tip   ignore  

« First        Comments 6,360 - 6,399 of 9,648       Last »     Search these comments

6366   Onvacation   2023 Aug 8, 3:40pm  

I fought the law...
6367   Onvacation   2023 Aug 8, 3:45pm  

"I had to steal the bike! The garage was open"
6378   richwicks   2023 Aug 8, 10:47pm  

Patrick says






Where's this place? I'd love to go to it.
6380   HeadSet   2023 Aug 9, 2:38pm  

The definition of luck:


6386   Onvacation   2023 Aug 11, 3:55pm  

Almost half west Asian...

original link
6388   richwicks   2023 Aug 12, 10:05pm  

Patrick says





This animal is on the edge or over the edge of self awareness. It's recognizing it sees itself.
6389   Ceffer   2023 Aug 12, 10:09pm  

Onvacation says


Almost half west Asian...

Nothing worse than a Khazarian Mafia Iguana.



6390   RC2006   2023 Aug 13, 6:44am  

All this proves is the reason why jews are working with lizard people overlords.
6396   Maga_Chaos_Monkey   2023 Aug 13, 12:07pm  

Onvacation says

Almost half west Asian...


The lizard DNA won't bind to the beads in the Illumina bead chip microarray. (I used to help design them; 23andme buys them from ILMN) The swab was contaminated with human DNA. (sorry for the spoiler)
6397   Patrick   2023 Aug 13, 12:16pm  

@just_passing_through

My wife does not match a known 3rd cousin at all on 23andme. Yet the 3rd cousin and my wife both match with a 2nd cousin of my wife.

I think this is actually possible, because maybe the 3rd cousin just didn't happen to inherit enough overlap with my wife to be detectable.
6398   Maga_Chaos_Monkey   2023 Aug 13, 12:24pm  

Arrays are cheap and old technology. It's like taking a sample of a word from every page in a decent sized phone book. But super duper cheap. If you really want to do genetic analysis these days you'd use NGS (Next Generation Sequencing) capable of reading every word in the phone book. The step after that would be variant calling (typically) where your phone book is compared to a reference phone book and differences are noted. (outputs a VCF file if you care to dig into that)

The reason the lizard DNA isn't legit is the chip is covered in short sequences of human dna. Only complementary DNA (other strand of human DNA) would bind to it. Now if it were the case that 'some' of the lizard DNA just happened to bind it wouldn't be much and would fail QC. You'd at least need most of the beads hybridized with DNA to pass QC, thus, it's human DNA. Or the whole thing might just be BS.

There are dropouts in microarrays so that would explain your situation. A certain amount is tolerated. Same with NGS sequencing but it's called missing coverage - you just don't get a read over certain areas.. However good sequencing panel designs are aware of difficult regions and enrich for them.

Someday these ancestry companies will switch to sequencing but it's still ~$500-1K per genome. Most people wouldn't pay for that.
6399   Maga_Chaos_Monkey   2023 Aug 13, 12:28pm  

Patrick says





low concrete wall hidden behind the wooden fence.

« First        Comments 6,360 - 6,399 of 9,648       Last »     Search these comments

Please register to comment:

api   best comments   contact   latest images   memes   one year ago   random   suggestions   gaiste