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Efficacy of hydroxychloroquine against Wuhan virus


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2020 Mar 21, 10:47am   12,126 views  290 comments

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164   Onvacation   2020 Apr 1, 12:45pm  

rdm says

Give me one example of this from Biden?

Well, Corn-pop was a bad dude.
165   rdm   2020 Apr 1, 12:48pm  

socal2 says
Now a month later, CNN is reluctantly admitting that Trump was correct.
socal2 says
Here is Biden's big Coronavirus speech from a few weeks ago criticizing Trump's travel ban from China and Europe........calling Trump a xenophobe..........saying it wouldn't stop the virus.


For real?
That all you got to go up against Trumps continual blathering of misinformation and a way late, inadequate Federal response? He said the travel bans were not enough, not much if any PC. And do you disagree with anything else in the speech, was it factual? That travel bans may slow the virus but not stop it (this is true) and need to be put in place on a scientific basis rather than political. Never mentioned Trumps name. If we had used the travel bans and the several months they may have bought us constructively, rather than doing almost nothing, we would be in much better shape.

Fact of the matter is Biden wrote a piece for USA today back in January that pointed out the shortcomings of Trumps response, we would be in a much better position today if Biden's ideas had been followed rather than Trumps magical thinking of an April miracle.
https://www.usatoday.com/story/opinion/2020/01/27/coronavirus-donald-trump-made-us-less-prepared-joe-biden-column/4581710002/
166   socal2   2020 Apr 1, 1:30pm  

rdm says
And do you disagree with anything else in the speech, was it factual? That travel bans may slow the virus but not stop it (this is true) and need to be put in place on a scientific basis rather than political


Biden admits that travel bans would slow the spread, but he would not enact a ban because he would piss off his benefactors in China or put a stigma on Chinese Americans?

The only one acting politically on this issue is Biden and the Democrats putting our country's heath at peril.

rdm says
Fact of the matter is Biden wrote a piece for USA today back in January that pointed out the shortcomings of Trumps response, we would be in a much better position today if Biden's ideas had been followed rather than Trumps magical thinking of an April miracle.
https://www.usatoday.com/story/opinion/2020/01/27/coronavirus-donald-trump-made-us-less-prepared-joe-biden-column/4581710002/


An Op-Ed from Biden that spreads the lie that Trump disbanded the Pandemic team and cut the FDA and CDC?
https://www.politifact.com/factchecks/2020/feb/28/michael-bloomberg/did-donald-trump-fire-pandemic-officials-defund-cd/
https://www.factcheck.org/2020/03/dems-misconstrue-trump-budget-remarks/
168   WookieMan   2020 Apr 1, 2:07pm  

ThreeBays says
If HCQ was real, why are the only studies and 'evidence' bening presented by con artists?

Everything and everyone is a con artist in times like this. Trust nothing.
169   Bd6r   2020 Apr 1, 2:08pm  

ThreeBays says
If HCQ was real, why are the only studies and 'evidence' bening presented by con artists?

FDA is now participating in HCQ hoax:

https://www.fda.gov/media/136534/download

Based on the totality of scientific evidence available to FDA, it is reasonable to believe that chloroquine phosphate and hydroxychloroquine sulfate may be effective in treating COVID-19, and that, when used under the conditions described in this authorization, the known and potential benefits of chloroquine phosphate and hydroxychloroquine sulfate when used to treat COVID-19 outweigh the known and potential risks of such products.

I think our media libruls who bashed trump about this should apologize for it...but will never happen because ORANGEMAN BAD FOREVAH
170   WookieMan   2020 Apr 1, 2:14pm  

rd6B says
I think our media libruls who bashed trump about this should apologize for it...but will never happen because ORANGEMAN BAD FOREVAH

You know they're just going to say Trump ordered the FDA to do/say this. I'm no Trump fan boy, but he could cure cancer tomorrow and everyone would still be pissed off. It's become a joke at this point.
171   Bd6r   2020 Apr 1, 2:16pm  

and on a side note -
I have philosophical disagreements with trump with respect to fucking bailouts, but he has been such a paragon of intelligence relative to our media and libruls that I fail to see how his approval would not skyrocket when this is all over (unless economy collapses). He closed China border among librul screeching, he told people not to panic, now he is right about HCQ...being right over and over again, and media plants a minefield and then walks all over it themselves blowing their minuscule credibility leftovers to smithereens.
WookieMan says
You know they're just going to say Trump ordered the FDA to do/say this.

You're right, but fed bureaucracy does not work like that. They will not stick their necks out unless they are 120% sure about being right.
172   Rin   2020 Apr 1, 2:34pm  

WookieMan says
FOREVAH


Is that a Boston or a NY accent?

I think it's FOEVAH in Boston.
173   Heraclitusstudent   2020 Apr 1, 3:33pm  

Onvacation says
Do you really think all of the Trump's supporters blindly love him like Obama's did?

That's EXACTLY what the trumpsters are all doing in this thread.
174   socal2   2020 Apr 1, 3:45pm  

Heraclitusstudent says
That's EXACTLY what the trumpsters are all doing in this thread.


Because you all are putting up lame chicken-shit complaints and trying to polarize our country in a time of crisis.

- "He said he hoped the country would be open by Easter!"
- "He is hopeful and talking up hydroxchloroquine!"
- "He said Wuhan Virus!!!"

Of course Trumpers are going to circle the wagons over stupid complaints.

Besides, as of right now - the US is doing better than virtually every single modern Western European country in terms of deaths per capita - despite having a high population of obese and diabetic citizens and tens of thousands of Chinese flying into the country every single day up until Feb 1.
175   Heraclitusstudent   2020 Apr 1, 4:46pm  

That's all the fault of the infidels.
176   Onvacation   2020 Apr 1, 5:02pm  

Heraclitusstudent says
That's all the fault of the infidels.

You finally get it!
177   rdm   2020 Apr 1, 5:06pm  

socal2 says
Biden admits that travel bans would slow the spread, but he would not enact a ban because he would piss off his benefactors in China or put a stigma on Chinese Americans


Where does Biden say he wouldn't have enacted the travel ban(s)? Just make shit up, so we do just like the "media" one so complains about? That's the Trump play book

.socal2 says
An Op-Ed from Biden that spreads the lie that Trump disbanded the Pandemic team and cut the FDA and CDC?


Apparently reading comprehension is a problem too, don't know the difference between cut and proposed cuts? Which Trump absolutely did.

"He proposed draconian cuts to the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC) and the Agency for International Development — the very agencies we need to fight this outbreak and prevent future ones."
178   MisdemeanorRebel   2020 Apr 1, 5:16pm  

The most important chart. "IF ONLY WE HAD A NATIONAL HEALTH SERVICE!"

179   Bd6r   2020 Apr 1, 5:56pm  

Rin says
Is that a Boston or a NY accent?

I think it's FOEVAH in Boston.

German English
182   joshuatrio   2020 Apr 3, 6:09am  

BOOM!!!! Here you go @patrick:

https://www.citizenfreepress.com/breaking/laura-ingraham-bombshell-infectious-disease-md-reveals-results-of-hcq-trials/

Looks like we got a fix! How soon before they roll this out and the media stops hiding it?
183   theoakman   2020 Apr 3, 6:48am  

rdm says
Biden
rdm says
Where does Biden say he wouldn't have enacted the travel ban(s)? Just make shit up, so we do just like the "media" one so complains about? That's the Trump play boo


"We have, right now, a crisis with the coronavirus,” Biden said in Iowa Friday. “This is no time for Donald Trump’s record of hysteria and xenophobia – hysterical xenophobia – and fearmongering to lead the way instead of science"


That's clearly the words of someone who would have supported a travel ban from China. Dems were against it from the get go, and they used the WHO statements as their justification. After the Europe travel ban, the EU was against it, as were the Dems. Sorry...the left was late to the party and probably would have cost more lives initially. That's a fact. Trump should have shut the borders Jan 1st...unfortunately, the information just wasn't out there to justify that at the time. No country was fast enough to stop the entry and spread...none...it caught everyone by surprise. But the right actions were taken and initially fought by some.
184   Patrick   2020 Apr 3, 7:51am  

Patrick says


from https://public-cdn.sermo.com/covid19/c8/be4e/4edbd4/dbd4ba4ac5a3b3d9a479f99cc5/wave-i-sermo-covid-19-global-analysis-final.pdf


That same report shows Span and Italy have the highest use of hydroxychloroquine, at about 75% of doctors using it, which may help explain why their graphs of deaths are now flat.

The US has only 25% of doctors using it, and our death rate is still rising.

The hate for Trump is literally costing innocent lives. #TrumpPills
186   RWSGFY   2020 Apr 3, 5:22pm  

ThreeBays says
Welp, France might have done something to include more deaths in their statistics.



Ahh here's the reason.

On April 2, France reported 884 additional deaths that have occurred in nursing homes over the past days and weeks


#fuckingmorons
187   Patrick   2020 Apr 4, 11:53pm  

Another common drug might also work:

https://www.breitbart.com/border/2020/04/04/common-anti-parasite-drug-may-kill-coronavirus-in-under-48-hours-say-researchers/

Researchers in Australia report that Ivermectin, an FDA-approved drug commonly used to treat parasites, appears to be effective in treating the SARS-COV-2 coronavirus (COVID-19). The drug is widely available and can be “repurposed” for this application, doctors said.

The ScienceDirect journal, Antiviral Research, published an article by a group of Australian researchers from Monash University in Melbourne reporting that Ivermectin appears to be effective at inhibiting the coronavirus that causes COVID-19.

The article states:

Ivermectin is an inhibitor of the COVID-19 causative virus (SARS-CoV-2) in vitro.
A single treatment able to effect ∼5000-fold reduction in virus at 48h in cell culture.
Ivermectin is FDA-approved for parasitic infections, and therefore has a potential for repurposing.
Ivermectin is widely available, due to its inclusion on the WHO model list of essential medicines.
188   Tenpoundbass   2020 Apr 5, 6:27am  

It is amazing how everyone is dancing around the truth and racing to come up with an alternative for Chloroquine, because I'll be damned if they'll allow that Pompous Frog to get all of the credit for saving the World.

These people all need to be locked up and fed nothing but baloney and processed cheese.
189   Patrick   2020 Apr 5, 10:49am  

https://www.acsh.org/news/2020/03/26/problem-remdesivir-making-it-14665

Here's the important point of this article:

Two of the experimental coronavirus drugs, chloroquine, and hydroxychloroquine are a breeze to synthesize.


There should never be any real shortages of those.
190   HeadSet   2020 Apr 5, 11:41am  

Two of the experimental coronavirus drugs, chloroquine, and hydroxychloroquine are a breeze to synthesize.

No bear bile needed?
191   Patrick   2020 Apr 5, 11:50am  

Cool dashboard of clinical trials:

https://www.quiverquant.com/covidtreatments/
192   Rin   2020 Apr 5, 11:55am  

Ok, here is all that's needed, and just to be politically correct, the following is not approved by the FDA, it's just someone's speculation:

From the Russian-American doctor in NY... Zinc Sulfate, found in cold lozenges.

From the United Kingdom, active ingredient in garlic, Allicin: purified, stable, and bio-available. And for the trolls, not cooked or aged Garlic as all the Allicin there is gone. So please dispense with that bullshit rigged Stanford study. Here's the British website ( https://www.allicin.co.uk/section.php/2/1/about_us )

And now, for the main character in the play, Hydroxychloroquine, a.k.a Plaquenil.

This is it! And for a safety test, doctors can run an EKG on a patient, before and after, administrating a 25% dose of Plaquenil to see the person's physiology can handle it.
194   mell   2020 Apr 5, 10:22pm  

Yep. And here despicable leftoid lamestream media, the failing NYT: Orange man bad! pushing dangerous unproven drugs! Waah!

https://www.nytimes.com/2020/04/05/world/coronavirus-live-news-updates.html
195   marcus   2020 Apr 5, 10:49pm  

:
http://theconversation.com/a-small-trial-finds-that-hydroxychloroquine-is-not-effective-for-treating-coronavirus-135484

This talks about much more than that one small study. But who knows, maybe he's a paid shill by big pharma. Or maybe not.
197   Tenpoundbass   2020 Apr 6, 7:37am  

This really is a battle to the death, the Commie Democrats wants millions of deaths. Hang these mother fuckers until they shit their pants when it is proved that Trump Pills work and more importantly They Fucking Know it Does!

https://www.breitbart.com/politics/2020/04/06/democrat-tavia-galonski-trump-chloroquine-crimes-against-humanity/
198   Patrick   2020 Apr 6, 8:44am  

https://www.lemonde.fr/afrique/article/2020/04/06/l-afrique-potentiel-prochain-foyer-du-coronavirus-mise-sur-la-chloroquine_6035668_3212.html

Patients treated with hydroxychloroquine "heal faster," said Professor Moussa Seydi, head of the infectious disease department at Fann Hospital in Dakar, during a public address Thursday, April 2. “This finding reassures me and my teams. In the coming days, we are going to combine it with azithromycin, an antibiotic that would allow us to have better results, "he continued.
199   WookieMan   2020 Apr 6, 8:53am  

Patrick says
https://www.lemonde.fr/afrique/article/2020/04/06/l-afrique-potentiel-prochain-foyer-du-coronavirus-mise-sur-la-chloroquine_6035668_3212.html

Patients treated with hydroxychloroquine "heal faster," said Professor Moussa Seydi, head of the infectious disease department at Fann Hospital in Dakar, during a public address Thursday, April 2. “This finding reassures me and my teams. In the coming days, we are going to combine it with azithromycin, an antibiotic that would allow us to have better results, "he continued.

Wait until the first person is diagnosed as dying from the drug though because of a 1 in a million side effect and underlying condition. It's coming. Get the popcorn ready.
200   socal2   2020 Apr 6, 8:54am  

More "anecdotal" evidence.

*LA doctor seeing success with hydroxychloroquine to treat COVID-19*
Dr. Anthony Cardillo said he has seen very promising results when prescribing hydroxychloroquine in combination with zinc for the most severely-ill COVID-19 patients.

"Every patient I've prescribed it to has been very, very ill and within 8 to 12 hours, they were basically symptom-free," Cardillo told Eyewitness News. "So clinically I am seeing a resolution."
https://abc7.com/coronavirus-drug-covid-19-malaria-hydroxychloroquine/6079864/
201   Bd6r   2020 Apr 6, 1:07pm  

thomasdong1776 says
Fauci: no evidence anti-malaria drug pushed by Trump works against novel coronavirus

https://www.theguardian.com/world/2020/apr/05/coronavirus-fauci-trump-anti-malaria-drug

Let's see what Fauci says:

“In terms of science, I don’t think we can definitively say it works,” he told CBS’s Face the Nation.

“The data are really just at best suggestive. There have been cases that show there may be an effect and there are others to show there’s no effect.”

That does not qualify as Fauci saying that there is no evidence. He says "I don't think we can definitely say it works" which is different from headline and narrative of article, which, once more, shows that media are idiotic hacks.

Also, FDA says differently: https://www.fda.gov/media/136534/download

Based on the totality of scientific evidence available to FDA, it is reasonable to believe that chloroquine phosphate and hydroxychloroquine sulfate may be effective in treating COVID-19, and that, when used under the conditions described in this authorization, the known and potential benefits of chloroquine phosphate and hydroxychloroquine sulfate when used to treat COVID-19 outweigh the known and potential risks of such products.
202   rdm   2020 Apr 6, 2:28pm  

rd6B says
Based on the totality of scientific evidence available to FDA, it is reasonable to believe that chloroquine phosphate and hydroxychloroquine sulfate may be effective in treating COVID-19, and that, when used under the conditions described in this authorization, the known and potential benefits of chloroquine phosphate and hydroxychloroquine sulfate when used to treat COVID-19 outweigh the known and potential risks of such products.


All this says is that the FDA is now a politicized agency, really it always has been. Because " the totality of [real]scientific evidence available to FDA" is almost zero. Yes, there is the suggestion that it may have some effect, maybe a great effect and maybe no effect and it could simply be the placebo effect which can be significant. And Fauci is walking on eggshells, guarantee if Trump wasn't so gung ho on this he would be much harsher in his characterization of the purported treatment. Now I hear Trump is talking to Dr. Ozz and his trade rep Navaro and Rudi Giuliani as experts on the subject, hmmm doesn't that give one pause? Fortunately there are some real studies going on now, saw a guy from the University of Minnesota was working on two true double blind studies. Preliminary results may be fairly soon. I really hope it is effective as its cheap and available with side effects that are significant but usually tolerable, but will wait for the scientists to make that determination.
203   Bd6r   2020 Apr 6, 2:37pm  

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300808/

BMJ. 2003 Dec 20; 327(7429): 1459–1461.
doi: 10.1136/bmj.327.7429.1459

Objectives To determine whether parachutes are effective in preventing major trauma related to gravitational challenge.

Design Systematic review of randomised controlled trials.

Data sources: Medline, Web of Science, Embase, and the Cochrane Library databases; appropriate internet sites and citation lists.

Study selection: Studies showing the effects of using a parachute during free fall.

Main outcome measure Death or major trauma, defined as an injury severity score > 15.

Results We were unable to identify any randomised controlled trials of parachute intervention.

Conclusions As with many interventions intended to prevent ill health, the effectiveness of parachutes has not been subjected to rigorous evaluation by using randomised controlled trials. Advocates of evidence based medicine have criticised the adoption of interventions evaluated by using only observational data. We think that everyone might benefit if the most radical protagonists of evidence based medicine organised and participated in a double blind, randomised, placebo controlled, crossover trial of the parachute.

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