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Ivermectin


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2021 May 9, 10:24pm   81,877 views  629 comments

by Patrick   ➕follow (61)   💰tip   ignore  

https://sebastianrushworth.com/2021/05/09/update-on-ivermectin-for-covid-19/

Back in January I wrote an article about four randomized controlled trials of ivermectin as a treatment for covid-19 that had at that time released their results to the public. Each of those four trials had promising results, but each was also too small individually to show any meaningful impact on the hard outcomes we really care about, like death. When I meta-analyzed them together however, the results suddenly appeared very impressive. Here’s what that meta-analysis looked like:



It showed a massive 78% reduction in mortality in patients treated with covid-19. Mortality is the hardest of hard end points, which means it’s the hardest for researchers to manipulate and therefore the least open to bias. Either someone’s dead, or they’re alive. End of story.

You would have thought that this strong overall signal of benefit in the midst of a pandemic would have mobilized the powers that be to arrange multiple large randomized trials to confirm these results as quickly as possible, and that the major medical journals would be falling over each other to be the first to publish these studies.

That hasn’t happened.

Rather the opposite, in fact. South Africa has even gone so far as to ban doctors from using ivermectin on covid-19 patients. And as far as I can tell, most of the discussion about ivermectin in mainstream media (and in the medical press) has centred not around its relative merits, but more around how its proponents are clearly deluded tin foil hat wearing crazies who are using social media to manipulate the masses.

In spite of this, trial results have continued to appear. That means we should now be able to conclude with even greater certainty whether or not ivermectin is effective against covid-19. Since there are so many of these trials popping up now, I’ve decided to limit the discussion here only to the ones I’ve been able to find that had at least 150 participants, and that compared ivermectin to placebo (although I’ll add even the smaller trials I’ve found in to the updated meta-analysis at the end).

As before, it appears that rich western countries have very little interest in studying ivermectin as a treatment for covid. The three new trials that had at least 150 participants and compared ivermectin with placebo were conducted in Colombia, Iran, and Argentina. We’ll go through each in turn. ...

What we see is a 62% reduction in the relative risk of dying among covid patients treated with ivermectin. That would mean that ivermectin prevents roughly three out of five covid deaths. The reduction is statistically significant (p-value 0,004). In other words, the weight of evidence supporting ivermectin continues to pile up. It is now far stronger than the evidence that led to widespred use of remdesivir earlier in the pandemic, and the effect is much larger and more important (remdesivir was only ever shown to marginally decrease length of hospital stay, it was never shown to have any effect on risk of dying).

I understand why pharmaceutical companies don’t like ivermectin. It’s a cheap generic drug. Even Merck, the company that invented ivermectin, is doing it’s best to destroy the drug’s reputation at the moment. This can only be explained by the fact that Merck is currently developing two expensive new covid drugs, and doesn’t want an off-patent drug, which it can no longer make any profit from, competing with them.

The only reason I can think to understand why the broader medical establishment, however, is still so anti-ivermectin is that these studies have all been done outside the rich west. Apparently doctors and scientists outside North America and Western Europe can’t be trusted, unless they’re saying things that are in line with our pre-conceived notions.


And HCQ falls into that same bucket. Even worse - to admit HCQ works would be to admit Trump was right about something.

Liberals would rather that millions die than that Trump be allowed to be right about anything. They hate Trump more than they love their fellow humans.

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181   Robert Sproul   2021 Sep 6, 9:13pm  

Pierre Kory, MD MPA
@PierreKory
·
2h
Everything I’ve learned in the pandemic, everything I’ve fought for, fought against & and called attention to.. is perfectly described in this article. An education of a lifetime, should be taught to every high school, college or med student in the land.

https://www.thedesertreview.com/opinion/columnists/the-great-ivermectin-deworming-hoax/article_19b8f2a6-0f29-11ec-94c1-4725bf4978c6.html
185   Patrick   2021 Sep 6, 11:36pm  

https://www.yourobserver.com/article/the-battle-for-ivermectin

AUG. 18, 2021 2 weeks ago The battle for ivermectin
You need to read this magazine story. An old-school reporter shines light on a miracle drug and efforts to quash it.
by: Matt Walsh Editor & CEO
We are connecting you this week to an amazing, extraordinary story of a miracle drug that is “the most powerful COVID-19 killer known to science.”

You may have heard of it: ivermectin.

Ivermectin use in Florida

Are doctors and hospitals in Florida using ivermectin to treat COVID-19?

It appears the numbers are few. Doctors repeatedly have told journalist Michael Capuzzo the pressure against its use from the medical establishment and government agencies is unprecedented.

Nonetheless, cardiologist Dr. Bruce Boros, who operates three clinics in the Florida Keys, was among the first Florida physicians to surface as a prescriber of ivermectin.

Boros told the Miami Herald he had prescribed it as early as spring 2020 and that more than a dozen of his COVID-19 patients recovered after taking the drug.

In Broward County, Dr. Jean-Jacques Rajter, a Fort Lauderdale pulmonologist, also began prescribing ivermectin in April 2020 with successful outcomes. Soon after, the five-hospital Broward Health System approved the drug for use, one of the first and few hospital groups in Florida to do so.

When we polled the six hospitals in Sarasota and Manatee counties on whether they are allowing doctors to prescribe ivermectin, three hospitals responded before deadline:

Neither Blake Hospital in Bradenton nor Doctors Hospital in Sarasota, both owned by HCA Healthcare, is allowing the use of ivermectin.

“Ivermectin is not approved by the FDA for use in treating COVID-19 and has not been shown effective,” wrote Dr. Mitchell Rubinstein, Blake’s chief medical officer. “The FDA.gov website advises against using ivermectin.” ...

For information on ivermectin
FLCCC.net: The website of the Front Line COVID-19 Critical Care Alliance. It is teeming with information about ivermectin and treatments for COVID-19.
Journalists Michael and Teresa Capuzzo have started a new publication on Substack.com called RESCUE, independent reporting on the world’s best COVID-19 doctors and treatments. To get it delivered free to your inbox, contact them at Rescue@substack.com .

Dr. Paul Marik, famous in world medical circles, the second-most published critical care doctor in the history of medicine, told a former colleague of mine and friend, journalist Michael Capuzzo, if ivermectin “were universally distributed at a dose that costs 10 American cents in India and about the cost of a Big Mac in the U.S., ivermectin would save countless lives, crush variants, eliminate the need for endless big pharma booster shots and end the pandemic all over the world.”

That sounds like over-the-top, not-to-be-believed hype. But it’s not.

If you do anything today, or this week, you must read Capuzzo’s story, “The Drug That Cracked COVID,” which was published in the May edition of his and wife Teresa’s Pennsylvania magazine, Mountain Home.


https://cdn.digitalobservermedia.com/yourobserver.com/pdfs/The-Drug-that-Cracked-Covid-by-Michael-Capuzzo.pdf
187   Patrick   2021 Sep 7, 9:42am  

https://spectatorworld.com/topic/ivermectin-horse-skeptics-joe-rogan-covid/

The ivermectin skeptics
Horse dewormer or miracle drug?

September 5, 2021 | 10:58 am

... Pfizer had the first vaccine ready to go before the 2020 election, but selflessly waited until just after the election to make the announcement. They, and the other drug companies in on Operation Warp Speed, have been playing the opening bars of Pink Floyd’s song ‘Money’ nonstop at corporate headquarters ever since. Everyone must be vaccinated, twice (plus boosters) at government (i.e. taxpayer) expense immediately and forever. ...

He showed me a few boxes of ivermectin, told me it was probably an effective therapeutic but it had some serious disadvantages, chief among them is that it was very cheap, and therefore was unsupported by Big Pharma. Consequently, the experts looked down their noses at it, so far down that the politicians, who like the contributions they get from drug companies, basically outlawed its use for COVID. If he prescribed it for COVID, he told me, he could lose his license to practice medicine. ...

Was the recovery propter hoc, because of the ivermectin and other agents, or merely post hoc? Who knows?

But I do know this. It is utterly irresponsible for the establishment media machine to to trash ivermectin categorically. NBC, for example, in reporting Rogan’s diagnosis, screamed that he was taking the ‘widely discredited drug ivermectin’.

Discredited by whom? By St Anthony Fauci, maybe, and Big Pharma, for whom the media acts as PR flaks. ...

The current hostility to ivermectin is of a piece with the earlier hostility to hydroxychloroquine: it was cheap, Donald Trump took it, it must be bad. What really is bad are the proliferating health nazis who are sprouting up like mushrooms — toadstools — everywhere. In some places — Australia, for example, they come bearing the police power of the state and are harassing and incarcerating people for going about their everyday lives. It’s ridiculous. COVID, the original and all its variations thus far, is dangerous to a tiny part of the population. For most of us, it is no more (but also no less) dangerous than the flu. Sure, we should wash our hands and if you are vulnerable you should be take measures to isolate yourselves from risky situations. If I were you, I would also consider stocking up on ivermectin and the other items of Joe Rogan’s cocktail.
188   Patrick   2021 Sep 7, 9:49am  

Joe Rogan Criticized As 'Anti-Science' For Surviving COVID


https://babylonbee.com/news/progressives-outraged-as-another-person-recovers-from-covid

Joe Rogan: 'I'm Doing Better But I'm Still A Little Hoarse'
189   mell   2021 Sep 7, 9:56am  

Patrick says
Joe Rogan: 'I'm Doing Better But I'm Still A Little Hoarse'


should read: 'I'm Doing Better But I'm Still A Little Horse(paste)'
192   Patrick   2021 Sep 8, 2:11pm  

Exactly.

The Pfizer-government complex must prevent all cheap and effective cures or their whole EUA lie about the necessity for mandating the jab falls apart.
193   Robert Sproul   2021 Sep 8, 4:48pm  

Extremely well written series on 'mectin. The whole story, worthy of rubbing your favorite loony-horse-paste-lefty's nose in. I'm sending to my old pal who always claims she believes "the science" when she really just believes "the TV".
https://rescue.substack.com/p/the-drug-that-cracked-covid-part
https://rescue.substack.com/p/the-drug-that-cracked-covid-part-ab9
https://rescue.substack.com/p/the-drug-that-cracked-covid-part-0b9
195   Patrick   2021 Sep 10, 10:32am  

https://rescue.substack.com/p/pierre-kory-responds-to-critics-hollywood?token=patrick.net


Pierre Kory Responds to Critics, Hollywood Style

How does this passionate New York City-born liberal like it when he reads The Washington Post headline: “How the right’s ivermectin conspiracy theories led to people buying horse dewormer.” In other words, how does he handle all the horse-#&%@ that has been piled on ivermectin the past couple weeks?

He doesn’t like it. He loves it. “Bring it on!” Kory often tells his 120,000 Twitter followers. Nobody ever debates Kory. Here’s why: Kory’s technical round knockout of Dr. Garegnani.

So he was delighted when Florida newspaper publisher Matt Walsh asked him to respond to a ferocious critic of the newspaper’s ivermectin coverage, a critic with real credentials—a University of Michigan professor—in a Q&A debate. “I’ve never had more fun than answering these questions,” Kory says. “It was like shooting fish in a barrel.” ...

Dr. Pierre Kory responds: 63 positive studies exceed most approved drugs
The most easily quantifiable way to describe the indefensible lack of “approval” for ivermectin in COVID-19 is to note the actual amount of supportive clinical trials evidence in COVID-19, both randomized (31) and observational (32), including more than 26,000 patients with the near majority of all studies finding at least some important benefit with treatment.
198   mell   2021 Sep 11, 9:02am  

just_passing_through says
Rin's recipe with a horse paste twist:

http://orthomolecular.org/resources/omns/v17n15.shtml


I'm still positing that sars cov2 is mainly a respiratory virus where it usually does not leave lasting damage (most of the lung damage was from developed pneumonia as confection). However whenever viruses "escape" their infection habitat they can have serious effects, such as high inflammation/clotting in other organs. This is common to many viruses or bacteria and not a unique feature of sars cov2. For example, there are bacteria which are normally found in the mouth region causing no symptoms but when they escape into the GI tract or other parts of the body (e.g. after Trauma/surgery) they can cause serious symptoms. The goal should be to let the infection play out in the resp. tract while reducing viral load actively.
199   Patrick   2021 Sep 11, 10:21am  

https://www.tga.gov.au/media-release/new-restrictions-prescribing-ivermectin-covid-19




It is nothing short of criminal to prohibit doctors from using a life-saving drug.
200   Maga_Chaos_Monkey   2021 Sep 11, 11:21am  

mell says
For example, there are bacteria which are normally found in the mouth region causing no symptoms but when they escape


Those are called opportunistic infections.
201   mell   2021 Sep 11, 11:40am  

just_passing_through says
mell says
For example, there are bacteria which are normally found in the mouth region causing no symptoms but when they escape


Those are called opportunistic infections.


Right. And there are several streptococcus and other species that live in the mouth and cause great havoc if they escape and cause opportunistic infections in other areas of the body (heart, gi tract etc.). I believe sars cov2 is not much different and should be contained to the upper respiratory tract if possible with medications and general good health.
202   Maga_Chaos_Monkey   2021 Sep 11, 11:42am  

mell says
I'm still positing that sars cov2 is mainly a respiratory virus


It is... Some people, I think I've heard Malone above say it, think that perhaps the spike protein was engineered to cause clotting etc., I really don't know. Out of my domain.

Naturally I've understood it infects any cells with an ACE-2 receptor. mRNA vaccines on the other hand can potentially go everywhere.
203   Rin   2021 Sep 11, 5:43pm  

just_passing_through says
Rin's recipe with a horse paste twist:

http://orthomolecular.org/resources/omns/v17n15.shtml


The only thing I'd change on that web site is the fact that both HCQ and Ivermectin are Rx pharmaceuticals, re-purposed for Covid-19, whereas the Rin Pill, Quercetin (or better yet, Quercetin Phytosome) is an all natural dietary supplement.

There is absolutely nothing that the FDA can do to it but slander it or its vendors from saying that it has any effect against Covid, which is fine because some customers can say, "Not only have my allergies subsided but my PCRs for Covid have been negative for the entire past year". The FDA can't throw that customer in jail, only say that he's naive or stupid and remind the vendor that it can't put testimonials on its shipping label but on its website site as an opinion piece/testimonial.
204   Rin   2021 Sep 11, 6:18pm  

just_passing_through says
mell says
For example, there are bacteria which are normally found in the mouth region causing no symptoms but when they escape


Those are called opportunistic infections.


See Rin's Allisure Allicin, it's got a synergy, on the antiviral side as an immunomodulatory agent and on the antibacterial side, containing [ though not 100% eliminating ] the growth of bacterial pathogens w/o the side effects of an antibiotic.
205   Maga_Chaos_Monkey   2021 Sep 11, 9:48pm  

Rin says
Not only have my allergies subsided


I wish I could say that; maybe I will, it's only been about 6 weeks for me so far.
206   Maga_Chaos_Monkey   2021 Sep 11, 9:49pm  

Rin says
Allicin


That was something that was commonly yacked about in the molecular genetics lab I worked in during the late 90s.
207   Maga_Chaos_Monkey   2021 Sep 11, 9:53pm  

mell says
Right. And there are several streptococcus and other species


Yup, 'commonly opportunistic pathogens'.

I used to play with those in my 'micro'biology lab class in school. Fun stuff! Get to play with Bunsen burners, douse the bench with EtOH and light it ON FIRE! to sterilize the work area (mol-bio does this as well but by then that's not the cool stuff)

That class smelled like shit some days though. Depending on what we were growing.
208   Rin   2021 Sep 12, 10:49am  

just_passing_through says

I wish I could say that; maybe I will, it's only been about 6 weeks for me so far.


If you're using Quercetin Dihydrate, drop it, and buy the Quercetin Phytosome.

The former is not very bioavailable and needs all kinds of adjuvants like Bromelain and Olive oil to get any absorption. So for most Dihydrate users, they need to use massive doses like some 2000 to 3000 mg per day to get the same effects as 750-1000 mg of the Phytosome one.
209   Rin   2021 Sep 12, 10:51am  

just_passing_through says
Get to play with Bunsen burners, douse the bench with EtOH and light it ON FIRE! to sterilize the work area


I know of one guy in my lab section, who got kicked out of the group, due to such a stunt in front of the TA.
210   Maga_Chaos_Monkey   2021 Sep 12, 12:12pm  

Rin says
I know of one guy in my lab section, who got kicked out of the group, due to such a stunt in front of the TA.


Odd, that is sterilization protocol.
211   Maga_Chaos_Monkey   2021 Sep 12, 12:13pm  

Rin says
If you're using Quercetin Dihydrate, drop it, and buy the Quercetin Phytosome.


I have Phytosome.
212   Maga_Chaos_Monkey   2021 Sep 12, 12:15pm  

Rin says
who got kicked out


I probably would have been disciplined at least if it was ever found out I was the guy putting dry ice into micro centrifuge tubes and depositing into the trash can of a co-worker I liked to eff with. When they exploded they'd often hit the ceiling.
213   Robert Sproul   2021 Sep 12, 12:33pm  

Rin says
If you're using Quercetin Dihydrate, drop it, and buy the Quercetin Phytosome.

Dang it I just reordered. Q is getting scarce on the online vitamin sites BTW. If it doesn't specify on the bottle it is Dihydrate do you reckon?
214   Rin   2021 Sep 12, 5:22pm  

Robert Sproul says
If it doesn't specify on the bottle it is Dihydrate do you reckon?


It should say Quercetin Dihydrate in the ingredient list, not on the label.
215   Rin   2021 Sep 12, 5:23pm  

just_passing_through says
I have Phytosome.


The ppl I know, who got rid of their allergies, used some 2000 mg of Turmeric w/ bioperine along with 1000 mg of Quercetin.
216   Maga_Chaos_Monkey   2021 Sep 12, 5:40pm  

I eat a little tumeric with eggs (plus pepper and bacon fat) each morning but that much, nor have I tried that high of a Quercetin dose. I'll try it out.
217   Patrick   2021 Sep 12, 5:43pm  

Mmmm, bacon fat. I used to throw it out, but that was insane!

It's tastier than butter, and a "free" byproduct of cooking bacon. And I honestly think it's not that bad for you.

I really like turmeric too. My sister sent me a big container of it and it makes a nice addition to lots of things for the flavor. And if there really is a health benefit, then that's a bonus.
218   Maga_Chaos_Monkey   2021 Sep 12, 5:46pm  

Patrick says
And I honestly think it's not that bad for you.


It isn't. Fat doesn't make you fat, low fat food items do. Shit the store that says fat free or low fat I stay away from.

You need saturated fat for your brain among other things.

Just stay away from polyunsaturated fats - what they've been pushing on us the past 50 years. "vegetable oil" is really "seed oil", full of omega-6 which is highly inflammatory and will fuck up your arteries.

Eat butter too. And olive oil, coconut oil, avacado oil and beef tallow.
219   Maga_Chaos_Monkey   2021 Sep 12, 5:48pm  

Patrick says
I really like turmeric too.


I have a big bin of it but to make it work pharmaceutically it needs to be fresh and mine isn't. Buy the root and grind it yourself and eat it within 2-3 weeks. The sooner the better.

Otherwise it's just adding color and flavor.
220   Patrick   2021 Sep 12, 5:51pm  

just_passing_through says
Eat butter too. And olive oil, coconut oil, avacado oil and beef tallow.



I am a convert to your religion!

They all sound good to me.

I like fresh turmeric too, it's kind of like ginger.

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