Friday Hope: Walnuts: Improving Endothelial/Microvascular Function, Reducing Inflammatory Cytokines and Perhaps Helping Those with Post COVID/Spike Protein Induced Heart Failure This pantry staple used in everything from salads to desserts offers many benefits just by being included in an ad libitum diet. WALTER M CHESNUT AUG 8
Friday Hope: Walnuts: Improving Endothelial/Microvascular Function, Reducing Inflammatory Cytokines and Perhaps Helping Those with Post COVID/Spike Protein Induced Heart Failure This pantry staple used in everything from salads to desserts offers many benefits just by being included in an ad libitum diet. WALTER M CHESNUT AUG 8
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It is amazing. Simply adding two ounces of walnuts per day to your diet over time has been shown to have a significant effect on improving endothelial function. There is additionally a concurrent beneficial effect (though just shy of statistical significance) of controlling blood pressure.
The daily addition of 56 g of walnuts to the diet for 8 weeks significantly improved endothelial function in overweight adults with visceral obesity as compared with an ad libitum diet not supplemented with walnuts. A beneficial trend in systolic blood pressure reduction was observed that did not quite reach statistical significance. Despite the walnut dose representing more than 350 kcal, weight gain was not observed in the walnut treatment arm of the study, and the addition of walnuts was even associated with a decline in waist circumference.
This is wonderful news for all of us in this era of the Spike Protein. We now have one more completely natural food that can help combat the effects of SARS-CoV-2 and its Spike Protein. It is very likely that somewhere in your pantry you have walnuts at this very moment.
The microvasculature is also a known target of SARS-CoV-2 and its Spike Protein. Here, too, there is evidence that walnuts improve microvasculature function.
Microvascular function, assessed as the reactive hyperemia index (RHI), was the primary outcome measure, with serum lipids and plasma epoxides as secondary measures. Compared to 5 g of daily walnut intake, consuming 40 g/d of walnuts for 4 weeks increased the RHI and Framingham RHI. Total cholesterol and low- and high-density cholesterol did not significantly change after walnut intake. The change in RHI after 4 weeks of walnut intake was associated with the change in the sum of plasma epoxides (r=0.65, P=.002) but not with the change in the sum of plasma hydroxyeicosatetraenoic acids. Of the individual plasma epoxides, arachidonic-acid-derived 14(15)-epoxyeicosatrienoic acid was most strongly associated with the change in microvascular function (r=0.72, P<.001). These data support the concept that the intake of walnut-derived fatty acids can favorably affect plasma epoxide production, resulting in improved microvascular function.
Of course, excessive expression of inflammatory cytokines (cytokine storm) is one of the most well-known effects of SARS-CoV-2 and its Spike Protein on the body. Walnuts are able to ameliorate this. A study was conducted which looked at black walnuts, in particular.
We demonstrated cytokine suppressive properties of black walnut extracts using the human promonocytic cell line U-937. Black walnut kernels contain a wealth of bioactive metabolites putatively identified through a metabolomics approach. The five cultivars (Daniel, Mystry, Sparks, Sparrow, and Surprise) tested showed differences in their ability to inhibit the secretion of six cytokines/chemokines (TNF-α, IL-1β, IL-6, IL-8, IL-10, and MCP-1). Sparrow and Surprise showed the strongest inhibitory effects on the secretion of all measured cytokines. Mystry reduced the secretion of IL-6, IL-10, and MCP-1, while Daniel and Sparks only reduced the production of IL-6. Our findings reveal that certain black walnut cultivars may represent promising preventive agents for inflammatory diseases.
Black Walnut (Juglans nigra) Extracts Inhibit Proinflammatory Cytokine Production From Lipopolysaccharide-Stimulated Human Promonocytic Cell Line U-937 https://pmc.ncbi.nlm.nih.gov/articles/PMC6761373/
There is also some hope for those who suffer from heart failure brought on by COVID infection/Spike Protein injury/disease. The black walnut tree possesses a compound which is cardioprotective.
Juglone, a phenolic compound from the black walnut tree (Juglans nigra) can be used as a potential cardioprotective therapeutic agent in elevating the activity of SOD (superoxide dismutase), decreasing oxidative stress, activating the MAPK signalling pathway [239].
Apart from COVID/Spike Protein specific benefits, walnuts also have shown to help improve our blood lipid profiles, a cardiovascular risk factor. They appear to do this without promoting weight gain, which is splendid as they are also delicious.
Twenty-six clinical trials with a total of 1059 participants were included. The following weighted mean differences (WMDs) in reductions were obtained for walnut-enriched diets compared with control groups: -6.99 mg/dL (95% CI: -9.39, -4.58 mg/dL; P < 0.001) (3.25% greater reduction) for total blood cholesterol (TC) and -5.51 mg/dL (95% CI: -7.72, -3.29 mg/dL; P < 0.001) (3.73% greater reduction) for low-density lipoprotein (LDL) cholesterol. Triglyceride concentrations were also reduced in walnut-enriched diets compared with control [WMD = -4.69 (95% CI: -8.93, -0.45); P = 0.03; 5.52% greater reduction]. More pronounced reductions in blood lipids were observed when walnut interventions were compared with American and Western diets [WMD for TC = -12.30 (95% CI: -23.17, -1.43) and for LDL = -8.28 (95% CI: -13.04, -3.51); P < 0.001]. Apolipoprotein B (mg/dL) was also reduced significantly more on walnut-enriched diets compared with control groups [WMD = -3.74 (95% CI: -6.51, -0.97); P = 0.008] and a trend towards a reduction was observed for apolipoprotein A [WMD = -2.91 (95% CI: -5.98, 0.08); P = 0.057].
Effects of walnut consumption on blood lipids and other cardiovascular risk factors: an updated meta-analysis and systematic review of controlled trials https://pubmed.ncbi.nlm.nih.gov/29931130/
Of course, and especially with regard to the tree oils, always consult your Primary Care Provider before using any supplement or medication.
To quote the title of a song from the decade of my youth, “The Heat is On” here in northern Vermont. Canadian wildfire smoke hangs heavy in the air and we will be moving up from the 80s into the 90s over the weekend and into next week. Thank God for the glories of Autumn in Vermont, they are a superb reward for enduring the hot summer.
Thank you, as always, for your continued support, readership and dialogue. Please have a blessed weekend.
I will always keep my work free and available to all. Of the 14,139 subscribers, 358 are paid subscribers, which is 2.5%. I am extremely thankful for this support. It is an important goal to reach 700 paid subscribers to keep my work financially sustainable. Please consider becomine a paid subscriber, if you are not already one. If one in every forty subscribers were to become a paid subscriber today, the sustainability goal would be reached. “Donating a Coffee” once a month will keep these engines running. Still, I will continue to work and report back to you, which has always been an honor. 星期五希望：核桃：改善内皮/微血管功能，减少炎症细胞因子，也许有助于患有Covid /尖刺蛋白诱导的心力衰竭的那些储层钉从沙拉到甜点中的一切 Walter M Chesnut 8月8日阅读应用程序很棒。 随着时间的推移，只需为您的饮食添加两盎司的核桃，已经显示出对改善内皮功能的显着影响。 另外还有一个并发的有益效果（虽然只是害羞的统计显着性）控制血压。 每日添加56克核桃到饮食中的8周，显着提高了内皮功能，其超重成年人的内皮功能与内脏肥胖相比，没有补充核桃的广告性饮食。 观察到收缩压减少的有益趋势并没有完全达到统计学意义。 尽管核桃剂量代表了350多千卡，但在研究的核桃治疗臂中未观察到体重增加，并且加入核桃甚至与腰围的下降相关。 核桃对内皮肥胖的超重成人内皮功能的影响：随机，受控，交叉试验HTTPS：//www.tandfonline.com/doi/full/10.1080/07315724。 我们现在有一种更完全的天然食物，可以帮助解决SARS-COV-2及其尖峰蛋白的影响。 很可能在你的食品室里的某个地方你有核桃在这个时刻。 微血管特征也是SARS-COV-2及其尖峰蛋白的已知靶标。 这里也有证据表明核桃改善了微血管结构功能。 作为反应性高血量指数（RHI）评估的微血管功能是主要的结果测量，血清脂质和血浆环氧化物作为次要措施。 与5克日常的核桃摄入量相比，40克/天核桃4周增加了Rhi和Framingham Rhi。 在核桃摄入后，总胆固醇和低密度和高密度胆固醇没有显着变化。 核桃摄入4周后Rhi的变化与血浆环氧化物和（R = 0.65，P = .002）的变化有关，但不是血浆羟基辛酸四烯酸和的变化。 在单独的血浆环氧化物中，与微血管功能的变化（R = 0.72，P <0.001）的变化最强烈地相关的单独血浆环氧化物。 这些数据支持核桃衍生脂肪酸的摄入能够有利地影响血浆环氧化物产生的概念，导致微血管功能改善。 短期核桃消耗对人微血管功能及其与血浆环氧化物含量的影响HTTPS://www.scienceRect.com/science/article/abs/pii/s095528631500176 核桃能够改善这一点。 进行了一项研究，尤其考虑着黑核桃。 我们使用人普罗金尼细胞系U-937证明了黑核桃提取物的细胞因子抑制性能。 黑核桃仁含有一定程度的生物活性代谢物，通过代谢组方法识别。 测试的五种品种（丹尼尔，神秘，火花，麻雀和惊喜）表现出抑制六种细胞因子/趋化因子的分泌的能力差异（TNF-α，IL-1β，IL-6，IL 麻雀和惊喜显示出对所有测量细胞因子的分泌的最强的抑制作用。 Mystry减少了IL-6，IL-10和MCP-1的分泌，而Daniel和Sparks仅降低了IL-6的产生。 我们的研究结果表明，某些黑核桃品种可能代表炎症性疾病的有前途预防剂。 黑核桃（Juglans Nigra）提取物从脂多糖刺激的人普罗新醛细胞系U-937 HTTPS://pmc.ncbi.nlm.抑制抑制促炎细胞因子生产。 黑核桃树具有含有心脏保护的化合物。 juglone，来自黑核桃树（Juglans nigra）的酚类化合物可以用作潜在的心脏保护治疗剂，以提高SOD（超氧化物歧化酶）的活性，降低氧化应激，激活 用于缓解Covid-19危机的植物化学物质：来自临床前和临床研究的证据HTTPS：//www.explorationpub.com/journals/eds/article/100824除Covid / Spike之外 他们似乎在没有促进体重增加的情况下这样做，这很灿烂，因为它们也很美味。 包括共有1059名参与者的二十六项临床试验。 与对照组相比，得到以下加权平均差异（WMDS），用于富含核桃富含的饮食：-6.99mg / dl（95％Ci：-9.39，-4.58mg / dl; p <0.001） 与对照相比，富含甘油三酯浓度的浓度也降低了核桃富含饮食[WMD = -4.69（95％CI：-8.93，-0.45）; p = 0.03; 减少5.52％]。 当核桃干预与美国和西方饮食进行比较时，观察到血脂中更明显的血脂减少[Tc = -12.30（95％Ci：-23.17，-1.43）和LDL = -8.2 p <0.001]。 与对照组相比，载脂蛋白B（Mg / D1）也比核桃富含饮食更低[WMD = -3.74（95％CI：-6.51，-0.97）; p = 0.008]和对载脂蛋白A [WMD = -2.91（95％CI：-5.98,0.08）进行减少的趋势; p = 0.057]。 核桃消耗对血脂和其他心血管危险因素的影响：一次性荟萃分析和对照试验的系统审查HTTPS://pubmed.ncbi.nlm.nih.gov/29931130/ 从我年轻时十年引出一首歌的标题，“热火正在靠近佛蒙特州”。 加拿大野火烟雾在空中沉重，我们将在周末从80年代到90年代，并进入下周。 感谢上帝为佛蒙特州秋天的荣耀，他们是持久炎热的夏天的奖励。 衷心感谢您继续支持，读者和对话。 请有一个幸福的周末。 我将始终保持工作，并可供所有工作。 在14,139名用户中，358名是支付用户，其价值2.5％。 我非常感谢这种支持。 达到700名付费订户的重要目标是保证我的工作经济可持续。 如果您尚未成为一个，请考虑成为一名付费订阅者。 如果每位40名订户都在今天成为支付订户，则将达到可持续发展目标。 “捐赠咖啡”一次每月一次会保持这些发动机运行。 尽管如此，我仍然会继续努力并报告给您，这一直是荣誉。
Friday Hope: Walnuts: Improving Endothelial/Microvascular Function, Reducing Inflammatory Cytokines and Perhaps Helping Those with Post COVID/Spike Protein Induced Heart Failure
This pantry staple used in everything from salads to desserts offers many benefits just by being included in an ad libitum diet.
WALTER M CHESNUT
AUG 8
https://open.substack.com/pub/wmcresearch/p/friday-hope-walnuts-improving-endothelialmicrova
周五希望：核桃：改善内皮/微血管功能，减少炎症性细胞因子，也许帮助那些患有新冠肺炎/尖峰蛋白诱导心力衰竭的人
这种用于从沙拉到甜点的储藏室主食，只要加入随意饮食，就能提供许多好处。
沃尔特·M·栗子
8月8日
Friday Hope: Walnuts: Improving Endothelial/Microvascular Function, Reducing Inflammatory Cytokines and Perhaps Helping Those with Post COVID/Spike Protein Induced Heart Failure
This pantry staple used in everything from salads to desserts offers many benefits just by being included in an ad libitum diet.
WALTER M CHESNUT
AUG 8
READ IN APP
It is amazing. Simply adding two ounces of walnuts per day to your diet over time has been shown to have a significant effect on improving endothelial function. There is additionally a concurrent beneficial effect (though just shy of statistical significance) of controlling blood pressure.
The daily addition of 56 g of walnuts to the diet for 8 weeks significantly improved endothelial function in overweight adults with visceral obesity as compared with an ad libitum diet not supplemented with walnuts. A beneficial trend in systolic blood pressure reduction was observed that did not quite reach statistical significance. Despite the walnut dose representing more than 350 kcal, weight gain was not observed in the walnut treatment arm of the study, and the addition of walnuts was even associated with a decline in waist circumference.
Effects of Walnuts on Endothelial Function in Overweight Adults with Visceral Obesity: A Randomized, Controlled, Crossover Trial
https://www.tandfonline.com/doi/full/10.1080/07315724.2012.10720468#d1e181
This is wonderful news for all of us in this era of the Spike Protein. We now have one more completely natural food that can help combat the effects of SARS-CoV-2 and its Spike Protein. It is very likely that somewhere in your pantry you have walnuts at this very moment.
The microvasculature is also a known target of SARS-CoV-2 and its Spike Protein. Here, too, there is evidence that walnuts improve microvasculature function.
Microvascular function, assessed as the reactive hyperemia index (RHI), was the primary outcome measure, with serum lipids and plasma epoxides as secondary measures. Compared to 5 g of daily walnut intake, consuming 40 g/d of walnuts for 4 weeks increased the RHI and Framingham RHI. Total cholesterol and low- and high-density cholesterol did not significantly change after walnut intake. The change in RHI after 4 weeks of walnut intake was associated with the change in the sum of plasma epoxides (r=0.65, P=.002) but not with the change in the sum of plasma hydroxyeicosatetraenoic acids. Of the individual plasma epoxides, arachidonic-acid-derived 14(15)-epoxyeicosatrienoic acid was most strongly associated with the change in microvascular function (r=0.72, P<.001). These data support the concept that the intake of walnut-derived fatty acids can favorably affect plasma epoxide production, resulting in improved microvascular function.
Effects of short-term walnut consumption on human microvascular function and its relationship to plasma epoxide content
https://www.sciencedirect.com/science/article/abs/pii/S095528631500176X
Of course, excessive expression of inflammatory cytokines (cytokine storm) is one of the most well-known effects of SARS-CoV-2 and its Spike Protein on the body. Walnuts are able to ameliorate this. A study was conducted which looked at black walnuts, in particular.
We demonstrated cytokine suppressive properties of black walnut extracts using the human promonocytic cell line U-937. Black walnut kernels contain a wealth of bioactive metabolites putatively identified through a metabolomics approach. The five cultivars (Daniel, Mystry, Sparks, Sparrow, and Surprise) tested showed differences in their ability to inhibit the secretion of six cytokines/chemokines (TNF-α, IL-1β, IL-6, IL-8, IL-10, and MCP-1). Sparrow and Surprise showed the strongest inhibitory effects on the secretion of all measured cytokines. Mystry reduced the secretion of IL-6, IL-10, and MCP-1, while Daniel and Sparks only reduced the production of IL-6. Our findings reveal that certain black walnut cultivars may represent promising preventive agents for inflammatory diseases.
Black Walnut (Juglans nigra) Extracts Inhibit Proinflammatory Cytokine Production From Lipopolysaccharide-Stimulated Human Promonocytic Cell Line U-937
https://pmc.ncbi.nlm.nih.gov/articles/PMC6761373/
There is also some hope for those who suffer from heart failure brought on by COVID infection/Spike Protein injury/disease. The black walnut tree possesses a compound which is cardioprotective.
Juglone, a phenolic compound from the black walnut tree (Juglans nigra) can be used as a potential cardioprotective therapeutic agent in elevating the activity of SOD (superoxide dismutase), decreasing oxidative stress, activating the MAPK signalling pathway [239].
Phytochemicals for mitigating the COVID-19 crisis: evidence from pre-clinical and clinical studies
https://www.explorationpub.com/Journals/eds/Article/100824
Apart from COVID/Spike Protein specific benefits, walnuts also have shown to help improve our blood lipid profiles, a cardiovascular risk factor. They appear to do this without promoting weight gain, which is splendid as they are also delicious.
Twenty-six clinical trials with a total of 1059 participants were included. The following weighted mean differences (WMDs) in reductions were obtained for walnut-enriched diets compared with control groups: -6.99 mg/dL (95% CI: -9.39, -4.58 mg/dL; P < 0.001) (3.25% greater reduction) for total blood cholesterol (TC) and -5.51 mg/dL (95% CI: -7.72, -3.29 mg/dL; P < 0.001) (3.73% greater reduction) for low-density lipoprotein (LDL) cholesterol. Triglyceride concentrations were also reduced in walnut-enriched diets compared with control [WMD = -4.69 (95% CI: -8.93, -0.45); P = 0.03; 5.52% greater reduction]. More pronounced reductions in blood lipids were observed when walnut interventions were compared with American and Western diets [WMD for TC = -12.30 (95% CI: -23.17, -1.43) and for LDL = -8.28 (95% CI: -13.04, -3.51); P < 0.001]. Apolipoprotein B (mg/dL) was also reduced significantly more on walnut-enriched diets compared with control groups [WMD = -3.74 (95% CI: -6.51, -0.97); P = 0.008] and a trend towards a reduction was observed for apolipoprotein A [WMD = -2.91 (95% CI: -5.98, 0.08); P = 0.057].
Effects of walnut consumption on blood lipids and other cardiovascular risk factors: an updated meta-analysis and systematic review of controlled trials
https://pubmed.ncbi.nlm.nih.gov/29931130/
Of course, and especially with regard to the tree oils, always consult your Primary Care Provider before using any supplement or medication.
To quote the title of a song from the decade of my youth, “The Heat is On” here in northern Vermont. Canadian wildfire smoke hangs heavy in the air and we will be moving up from the 80s into the 90s over the weekend and into next week. Thank God for the glories of Autumn in Vermont, they are a superb reward for enduring the hot summer.
Thank you, as always, for your continued support, readership and dialogue. Please have a blessed weekend.
I will always keep my work free and available to all. Of the 14,139 subscribers, 358 are paid subscribers, which is 2.5%. I am extremely thankful for this support. It is an important goal to reach 700 paid subscribers to keep my work financially sustainable. Please consider becomine a paid subscriber, if you are not already one. If one in every forty subscribers were to become a paid subscriber today, the sustainability goal would be reached. “Donating a Coffee” once a month will keep these engines running. Still, I will continue to work and report back to you, which has always been an honor. 星期五希望：核桃：改善内皮/微血管功能，减少炎症细胞因子，也许有助于患有Covid /尖刺蛋白诱导的心力衰竭的那些储层钉从沙拉到甜点中的一切 Walter M Chesnut 8月8日阅读应用程序很棒。 随着时间的推移，只需为您的饮食添加两盎司的核桃，已经显示出对改善内皮功能的显着影响。 另外还有一个并发的有益效果（虽然只是害羞的统计显着性）控制血压。 每日添加56克核桃到饮食中的8周，显着提高了内皮功能，其超重成年人的内皮功能与内脏肥胖相比，没有补充核桃的广告性饮食。 观察到收缩压减少的有益趋势并没有完全达到统计学意义。 尽管核桃剂量代表了350多千卡，但在研究的核桃治疗臂中未观察到体重增加，并且加入核桃甚至与腰围的下降相关。 核桃对内皮肥胖的超重成人内皮功能的影响：随机，受控，交叉试验HTTPS：//www.tandfonline.com/doi/full/10.1080/07315724。 我们现在有一种更完全的天然食物，可以帮助解决SARS-COV-2及其尖峰蛋白的影响。 很可能在你的食品室里的某个地方你有核桃在这个时刻。 微血管特征也是SARS-COV-2及其尖峰蛋白的已知靶标。 这里也有证据表明核桃改善了微血管结构功能。 作为反应性高血量指数（RHI）评估的微血管功能是主要的结果测量，血清脂质和血浆环氧化物作为次要措施。 与5克日常的核桃摄入量相比，40克/天核桃4周增加了Rhi和Framingham Rhi。 在核桃摄入后，总胆固醇和低密度和高密度胆固醇没有显着变化。 核桃摄入4周后Rhi的变化与血浆环氧化物和（R = 0.65，P = .002）的变化有关，但不是血浆羟基辛酸四烯酸和的变化。 在单独的血浆环氧化物中，与微血管功能的变化（R = 0.72，P <0.001）的变化最强烈地相关的单独血浆环氧化物。 这些数据支持核桃衍生脂肪酸的摄入能够有利地影响血浆环氧化物产生的概念，导致微血管功能改善。 短期核桃消耗对人微血管功能及其与血浆环氧化物含量的影响HTTPS://www.scienceRect.com/science/article/abs/pii/s095528631500176 核桃能够改善这一点。 进行了一项研究，尤其考虑着黑核桃。 我们使用人普罗金尼细胞系U-937证明了黑核桃提取物的细胞因子抑制性能。 黑核桃仁含有一定程度的生物活性代谢物，通过代谢组方法识别。 测试的五种品种（丹尼尔，神秘，火花，麻雀和惊喜）表现出抑制六种细胞因子/趋化因子的分泌的能力差异（TNF-α，IL-1β，IL-6，IL 麻雀和惊喜显示出对所有测量细胞因子的分泌的最强的抑制作用。 Mystry减少了IL-6，IL-10和MCP-1的分泌，而Daniel和Sparks仅降低了IL-6的产生。 我们的研究结果表明，某些黑核桃品种可能代表炎症性疾病的有前途预防剂。 黑核桃（Juglans Nigra）提取物从脂多糖刺激的人普罗新醛细胞系U-937 HTTPS://pmc.ncbi.nlm.抑制抑制促炎细胞因子生产。 黑核桃树具有含有心脏保护的化合物。 juglone，来自黑核桃树（Juglans nigra）的酚类化合物可以用作潜在的心脏保护治疗剂，以提高SOD（超氧化物歧化酶）的活性，降低氧化应激，激活 用于缓解Covid-19危机的植物化学物质：来自临床前和临床研究的证据HTTPS：//www.explorationpub.com/journals/eds/article/100824除Covid / Spike之外 他们似乎在没有促进体重增加的情况下这样做，这很灿烂，因为它们也很美味。 包括共有1059名参与者的二十六项临床试验。 与对照组相比，得到以下加权平均差异（WMDS），用于富含核桃富含的饮食：-6.99mg / dl（95％Ci：-9.39，-4.58mg / dl; p <0.001） 与对照相比，富含甘油三酯浓度的浓度也降低了核桃富含饮食[WMD = -4.69（95％CI：-8.93，-0.45）; p = 0.03; 减少5.52％]。 当核桃干预与美国和西方饮食进行比较时，观察到血脂中更明显的血脂减少[Tc = -12.30（95％Ci：-23.17，-1.43）和LDL = -8.2 p <0.001]。 与对照组相比，载脂蛋白B（Mg / D1）也比核桃富含饮食更低[WMD = -3.74（95％CI：-6.51，-0.97）; p = 0.008]和对载脂蛋白A [WMD = -2.91（95％CI：-5.98,0.08）进行减少的趋势; p = 0.057]。 核桃消耗对血脂和其他心血管危险因素的影响：一次性荟萃分析和对照试验的系统审查HTTPS://pubmed.ncbi.nlm.nih.gov/29931130/ 从我年轻时十年引出一首歌的标题，“热火正在靠近佛蒙特州”。 加拿大野火烟雾在空中沉重，我们将在周末从80年代到90年代，并进入下周。 感谢上帝为佛蒙特州秋天的荣耀，他们是持久炎热的夏天的奖励。 衷心感谢您继续支持，读者和对话。 请有一个幸福的周末。 我将始终保持工作，并可供所有工作。 在14,139名用户中，358名是支付用户，其价值2.5％。 我非常感谢这种支持。 达到700名付费订户的重要目标是保证我的工作经济可持续。 如果您尚未成为一个，请考虑成为一名付费订阅者。 如果每位40名订户都在今天成为支付订户，则将达到可持续发展目标。 “捐赠咖啡”一次每月一次会保持这些发动机运行。 尽管如此，我仍然会继续努力并报告给您，这一直是荣誉。