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Australians claim to have a cure: an HIV drug, and chloroquine


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2020 Mar 18, 9:57am   2,408 views  42 comments

by Patrick   ➕follow (61)   💰tip   ignore  

https://www.news.com.au/lifestyle/health/health-problems/coronavirus-australia-queensland-researchers-find-cure-want-drug-trial/news-story/93e7656da0cff4fc4d2c5e51706accb5

A team of Australian researchers say they’ve found a cure for the novel coronavirus and hope to have patients enrolled in a nationwide trial by the end of the month.

University of Queensland Centre for Clinical Research director Professor David Paterson told news.com.au today they have seen two drugs used to treat other conditions wipe out the virus in test tubes.

He said one of the medications, given to some of the first people to test positive for COVID-19 in Australia, had already resulted in “disappearance of the virus” and complete recovery from the infection.

Prof Paterson, who is also an infectious disease physician at the Royal Brisbane and Women’s Hospital, said it wasn’t a stretch to label the drugs “a treatment or a cure”.

“It’s a potentially effective treatment,” he said.

“Patients would end up with no viable coronavirus in their system at all after the end of therapy.”

The drugs are both already registered and available in Australia. ...

One of the two medications is a HIV drug, which has been superseded by “newer generation” HIV drugs, and the other is an anti-malaria drug called chloroquine which is rarely used and “kept on the shelf now” due to resistance to malaria. ...

“Our doctors were very, very surprised that a HIV drug could actually work against the novel coronavirus and there was a bit of scepticism,” he said.

“That first wave of Chinese patients we had (in Australia), they all did very, very well when they were treated with the HIV drug.

“That’s reassuring … that we’re onto something really good here.”


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22   Patrick   2020 Mar 18, 3:38pm  

But then, there's this:

https://lasvegassun.com/news/2020/mar/18/the-latest-disappointing-results-in-1st-chinese-vi/

A combination of two antiviral drugs that are used now to treat HIV — lopinavir and ritonavir — did not resolve symptoms quicker than usual care did. The study involving 199 hospitalized, severely ill patients was published Wednesday in the New England Journal of Medicine.

However, "intriguing" signs were seen in some other results. There were slightly fewer deaths among those given the drugs but the comparison group that received just usual care also was sicker, making this information hard to interpret, two editors wrote in an editorial in the journal.

Many other medicines are still being tested in various experiments including remdesivir, an experimental antiviral drug that has shown some promise against viruses similar to the one causing COVID-19.
23   marcus   2020 Mar 18, 3:40pm  

:
I'm glad other countries are moving ahead (competing) and we don't just have to wait for American big pharma to figure out how to cash in. Or do we ?
24   RWSGFY   2020 Mar 18, 3:43pm  

marcus says
:
I'm glad other countries are moving ahead (competing) and we don't just have to wait for American big pharma to figure out how to cash in. Or do we ?


We can always count on marcus to squeeze American-hating message into anything. Way to go, marcus-boy!
25   Patrick   2020 Mar 18, 3:43pm  

marcus says
If we did somehow force things to be made more expensively here (deciding that free trade and capitalism on a global scale doesn't work as we have always claimed it would) why doesn't that raise our cost of living ?


The question is this: who is "we"?

Yes, paying fair wages to Americans instead of outsourcing to China would cause many thing to cost more to consumers.

BUT: American workers would get that money, raising their wages, and allowing them to spend more. And poorer people immediately spend that extra income, benefiting the economy, unlike giving money to rich people, who throw it on the pile in the basement.

And we as a country would not be dependent on China and their extremely poor sanitation practices.

There is some balance to be struck, but the current massive dependency on China is stupid and shameful, definitely treason on the part of US executives.
26   Heraclitusstudent   2020 Mar 18, 3:47pm  

Patrick says
given to some of the first people to test positive for COVID-19 in Australia, had already resulted in “disappearance of the virus” and complete recovery from the infection.


Now you probably need large scale double blind experiments to prove it works and is safe, before these drugs are approved to treat this.

But if you are dying you may find a doctor willing to prescribe it to you anyway if they are not scared of losing their licenses.

I have heard Chinese used HIV drugs and also tried chloroquine.
I also read some French doctor also found chloroquine is efficient, but the guy looks like he escaped from Woodstock:
27   marcus   2020 Mar 18, 3:51pm  

:
I totally disagree. You haven't scratched the surface of convincing me that there is as shred of evidence to back up your assertions.

It's just pure dogma

This is the age of automation and AI coming. We need to be investing in education and preparing for new technologies, developing areas where we can compete. Where we must compete.

Worrying about china's low skills workers taking away our low skills workers jobs/wages is focusing on entirely the wrong thing. IT would make more sense for the govt to subsidize, in new and different ways, the pay of our low skills workers than to bark up that nonsensical tree.

(Perhaps Trumps massive tax cuts in 2017 should have been tied to hiring low skills workers (note by low skill, I simply mean not having skills that the market is paying much for now)).

And as I tried to explain, you either accept the idea of free trade or you don't. I wish I had the words to describe how little sense you make from my perspective.

Also, I have tried to show data in the past that indicates our manufacturing has not dropped nearly as much as manufacturing employment, and that is a function of using technologies productively.
28   marcus   2020 Mar 18, 3:57pm  

:
It's just part of Trumps bullshit con, to get the vote of people that don't understand whats going on. It's all lies.

Without Trump lying and sales skills he would have never been elected. I honestly believe he would be the first to agree with me on that, including the lying part. He does have moments of honesty, such as when he talks about how effective lying is in make the sale.

It's called taking advantage of the fact that so many people are going to believe what they want to believe.

But for some of this, it's basically the definition evil.
29   Shaman   2020 Mar 18, 4:02pm  

marcus says
Worrying about china's low skills workers taking away our low skills workers jobs/wages is focusing on entirely the wrong thing


Is that why Trump just enacted the National Production Defense Act? Seems like he needed to because China took that work and is now keeping the product as well. We have no medical supplies because they’ve all been outsourced to Asia! When you’re dying in a hospital bed without meds that could have saved you, just remember that outsourcing to China is not the problem!
30   Heraclitusstudent   2020 Mar 18, 4:05pm  

marcus says
Worrying about china's low skills workers taking away our low skills workers jobs/wages is focusing on entirely the wrong thing.


There are plenty that justifies worrying about it:
1 - the low skill workers in the US get screwed.
2 - China manipulated it's currency and kept its workers underpaid,
3 - we build an economy of buy buy buy, funded by debt debt debt, where everything is temporary held in place only by growing leverage. Everyone knows this will have to stop eventually. And when it happens (and we see the panic now as soon as the financial pyramid is hit) America will wake up poor, with few industries, with few skills, and dependent on China for everything.
4 - We built up a communist undemocratic government into the next superpower. It doesn't stop at low skills jobs. They are building computers chips, AI programs, OSs, rockets, communication networks, Social networks, etc, that are more advanced than what the US has. All subsidized by the government, and all backed by a billion customers.

In exchange of that what did we get?: instant gratification with cheap stuff, and an artificially standard of living for many decades.
Screw this.
31   marcus   2020 Mar 18, 4:20pm  

Heraclitusstudent says
In exchange of that what did we get?: instant gratification with cheap stuff, and an artificially standard of living for many decades.
Screw this.


I'm in agreement with a lot of what you said, but that's not about taking low paying jobs back from China.

Carter's malaise speech was correct, and we started going in the wrong direction in the Reagan's (debt doesn't matter) era. Ironically Dvid Stockman is one of the ones talking about this the most in the past decade or more.

Where I disagree is that it's about bringing back, seamstress or assembly line jobs.

We need to be making the best robots here. We need a few Elon Musks to get behind that. Or behind manufacturing drugs or anything else that can be automated where we can compete. If subsidizing worker pay is what it takes, then fine.

Heraclitusstudent says
instant gratification with cheap stuff, and an artificially standard of living for many decades


Yes, this is what Carter tried to warn us about, and Daddy (Reagan) came in to tell us "don't worry, be happy."

I don't see how that has ANYTHING to do with bringing assembly line level jobs from China to here. They won't pay better than Kinkos or starbucks. And there just aren't that many.
32   marcus   2020 Mar 18, 4:23pm  

:
Again, please see the gap between manufacturing in the US and manufacturing employment. That's about automation not China.
33   RWSGFY   2020 Mar 18, 4:39pm  

marcus says
Worrying about china's low skills workers taking away our low skills workers jobs/wages is focusing on entirely the wrong thing. IT would make more sense for the govt to subsidize, in new and different ways, the pay of our low skills workers than to bark up that nonsensical tree.


Huh? It's totally the right tree to bark and why would anybody need "new and different ways to subsidize the pay of our low skilles workers" when old ways of tariffs would do it pretty much automatically and transparently?

And no, it's not realistic to make every low-skilled worker into programmer/doctor/engineer: some people simply have no natural aptitude for that kind of thing no matter how much time and money you'll waste trying.
34   marcus   2020 Mar 18, 4:51pm  

TEOTWAWKI says
why would anybody need "new and different ways to subsidize the pay of our low skilles workers" when old ways of tariffs would do it pretty much automatically and transparently?


Thanks for asking. Actually the current way our country subsidizes low skills workers is food stamps and other aid to workers that can't pay their bills on Walmart wages or other market low level wages.

Ever wonder why Walmart doesn't have to pay workers more ? If American companies started making shirts here because we somehow managed to set the tarrifs that high, the pay to those employees would be just like the pay to walmart employees. Not enough, the govt provides food stamps or subsidized housing etc.

What I meant "new ways of subsidizing workers in new ways" is tax breaks, write offs or even credits or other indirect ways the government could support actually paying workers decently while companies can still compete globally. If we are going to deficit spend it should be in ways that really do trickle down, not by funding the investment accounts of the 1%.

Declaring through our actions that America is no longer for free trade is beyond retarded. It would end us.

By the way, this was largely proven long ago. But somehow right wing populism and demagoguery have brought the idea back. Never mind the evidence to the contrary.
35   Heraclitusstudent   2020 Mar 18, 5:31pm  

marcus says
Carter's malaise speech was correct, and we started going in the wrong direction in the Reagan's (debt doesn't matter) era.


The debt is just the result of massive imports. Reagan was facing high inflation and he found a simple answer: crush the US workers negotiating power using offshoring to workaround them (and immigration for low skills immigration in the US). Initially this was US companies producing abroad. Soon these were all Chinese companies as US skills, IP and capital were offered to the Chinese.

marcus says
That's about automation not China.

No it's not. Automation was happening all the time before Reagan, but it always resulted in better US worker s pay. Not throwing the entire lower half of the US under the bus.
Automation always meant more productivity. Workers move to more productive occupations and get paid more - and consume new things.
This equation stop applying when you add many hundreds of millions poor workers to the labor supply. Automation never disrupted the position of labor in the US this way.
36   RWSGFY   2020 Mar 18, 5:47pm  

marcus says
If American companies started making shirts here because we somehow managed to set the tarrifs that high, the pay to those employees would be just like the pay to walmart employees.


Why would the pay stay flat? Makes no sense. Right now walmart employees have no alternative and must agree to the low pay. If shirt/socks/TV/phone manufacturers move back to the US the workers will have a choice where to work and the salaries for BOTH walmart and shirt-making employees will have to go up simple because of increased competition for the same labour pool.
37   Patrick   2020 Mar 18, 5:57pm  

Heraclitusstudent says
In exchange of that what did we get?: instant gratification with cheap stuff, and an artificially standard of living for many decades.


The cheap stuff was just a justification for massive CEO bonuses for screwing America.

Really, all those CEOs should be shot. They put us in this position, with the help from paid-off Congressmen. That may explain why so many CEOs are suddenly "retiring". They know that the bill has come due, and people are going to be looking right at them.
38   Patrick   2020 Mar 18, 5:59pm  

OccasionalCortex says
Where do you think the capital for the vast majority of loans being made come from? The 'basement', that's where. :)



No, there is way too much money in the basement. All those loans could be made with only a fraction of what is sloshing around looking for something to do.

Most of the money that the rich have is doing nothing productive at all.
39   SunnyvaleCA   2020 Mar 18, 6:52pm  

Patrick says
SunnyvaleCA says
If only we had a president who would start a trade war with China. Then, even if manufacturing doesn't come back here, it'll be distributed to a variety of countries that the USA can man-handle into complying with our needs and whims. Such a president could be called a "stability genius" ... or just "stable genius" for short.


Can't tell if you're joking, but it actually does sound like a pretty good idea not to be dependent on China at all, for anything. Ever.

And to start executing US executives (ironic word) who outsource anything to China.
No. Not joking. The trade war has a variety of benefits. This is one of them.
40   HeadSet   2020 Mar 18, 7:28pm  

marcus says
:
Again, please see the gap between manufacturing in the US and manufacturing employment. That's about automation not China.


No. If that were the case, the items would be manufactured in America using all that technology. Manufacturing is only outsourced because China has lower costs due to slave labor and lax pollution laws. Nothing wrong with free trade, but an exception should be made when the only comparative advantage is allowing severe labor exploitation and zero environmental protection. Apple produces at Foxconn in China so they can make $400/phone vs a mere $200/phone by producing in the US.
41   Patrick   2020 Mar 19, 9:27am  

https://techstartups.com/2020/03/19/two-anti-malarial-drugs-chloroquine-and-hydroxychloroquine-show-early-promising-results-in-coronavirus-treatment-u-s-doctors-now-say/

As we reported yesterday night (New York Time), a new controlled clinical study conducted by doctors ​in France shows that Hydroxychloroquine is effective in the fight against coronavirus. The study, which was conducted by Didier Raoult​ M.D/Ph.D, et. al in France showed that 100% of patients that received a combination of HCQ and Azithromycin tested negative and were virologically cured within 6 days of treatment. Chloroquine and his sister drug, hydroxychloroquine, have been used to treat malaria since Word War II.
42   Heraclitusstudent   2020 Mar 19, 9:59am  

Patrick says
The cheap stuff was just a justification for massive CEO bonuses for screwing America.

The Chinese have been playing the greed card against our elites and it's been like shooting an elephant in a corridor.
I would bet most economic literature justifying the current framework is just motivated reasoning from elites. It would insist on stuff like "Americans get the benefit of cheaper products at the store." while blissfully ignoring the US doesn't even produce the income to buy these without debts. It would look at debt and just say: "It's normal for a richer nation to run an account deficit." without explaining in what sense we are richer: the fact we have better credit score.

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