patrick.net

California Gov. Gavin Newsom released a sweeping executive order on Thursday that allows the state to commandeer hotels and medical facilities to treat coronavirus patients and permits government officials to hold teleconferences in private without violating open meeting laws.

https://www.latimes.com/california/story/2020-03-12/california-governor-gavin-newsom-hotels-medical-facilities-patients-meeting-requirements

We’ve Got The Vaccine, Says Pentagon-Funded Company

BY PATRICK TUCKER
TECHNOLOGY EDITOR

MARCH 12, 2020

Canadian firm says it could make 10 million doses per month — if its innovative production method wins FDA approval.

A Canadian company says that it has produced a COVID-19 vaccine just 20 days after receiving the coronavirus’s genetic sequence, using a unique technology that they soon hope to submit for FDA approval.

Medicago CEO Bruce Clark said his company could produce as many as 10 million doses a month. If regulatory hurdles can be cleared, he said in a Thursday interview, the vaccine could start to become available in November.

An Israeli research lab has also claimed to have created a vaccine. But Clark says his company’s technique, which has already been proven effective in producing vaccines for seasonal flu, is more reliable and easier to scale.

“There are a couple of others who are claiming that they have — well, we will call them vaccine[s]” for COVID-19, he said. “But they’re different technologies. Some are RNA- or DNA-based vaccines that have not yet been proven in any indication yet, let alone this one. Hopefully, they’ll be successful.”

How did Clark’s team create one so quickly,? They use plants, not chicken eggs, as a bioreactor for growing vaccine proteins.

Traditional vaccine production requires eggs, a lot of them. Vaccine manufacturers inject the virus into the eggs, where it propagates. But using eggs is expensive, takes a long time, and is far from perfect. Mutations can yield vaccines that don’t match up to the virus they aim to shut down, Clark said

So Medicago doesn’t work with a live virus. Instead, it uses plants, a relatively new approach that has seen much advancement in the past decade. It inserts a genetic sequence into agrobacterium, a soil bacteria, which is taken up by plants — in this case, a close cousin to tobacco. The plant begins to produce the protein that can then be used as a vaccine. If the virus begins to mutate, as is expected for COVID-19, they can just update the production using new plants.

“That’s the difference between us” and egg-based methods, he said, ”we go directly to producing the vaccine or the antibody without having to propagate the virus.”


https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/163739/?oref=d-river

mell says

This is fucking retarded. I just ordered TP on Ebay from Kentucky. What is wrong with those preppers?! Was actually reasonably priced but there are tons of listing selling a 4 pack for $40. Farking peppers!

As weird as it sounds, I think most people are purchasing TP as a joke. My wife just did it when we have 60+ rolls in the closet. My neighbor and wife bought the last rolls on the shelf (that was fully stocked 5 hours prior) just because.

I wouldn't be surprised to find out later that this was a toilet paper manufacturer social media scheme to get a viral video out there. I'm not too worried about TP with what is no worse than the common flu. It's all a joke I think. I don't know one person taking this seriously. It's kind of weird....

From what I’ve seen, heard, and surmised, kids don’t really get COVID-19. They are carriers though. This is a blessing and a curse. A blessing because no kids have died except one newborn born with it in China... super special circumstances. A curse because the kids can spread this undercover. They’re running around healthy, maybe a little sniffle, and sharing the pathogen at school, then they give it to their parents or grandparents.

That’s going to be impossible to stop.

Interesting, eh?

"Don't call it the Wuhan Virus, that's Racist. But let's call it the Trumpvirus. Also, stop politicizing this deadly disease that is Trump's fault as it spread through communist China like wildfire and thus the world. Finally, none of the problems in the last few months are a wake up call about sourcing basic hygiene and medical supplies from China."

It's kinda nice to have something to distract everyone from all the electoral bullshit.

Maybe there should always be quarantines when visiting any foreign country. People would value international travel more if it were harder. And it was always kind of insane to shoot big tubes of people through the sky all day, all over the world, spreading every disease they catch to everywhere else. It's like having everyone in the world sharing needles in a way.

It's also good that our dependencies on China for drugs and manufacturing are made really clear by shortages.

There are some damn good arguments against globalization being made clear by this.

Patrick says

Maybe there should always be quarantines when visiting any foreign country.

If you plan to visit Sydney there is an interesting hotel there: it's called Q Station (where Q stands for "quarantine"). This is basically a well-preserved former quarantine station which was in use as such from early 1800 till mid 1980s. Staying there gives you a perspective on how the things were before "big tubes of people shooting through the sky all day".

Angel Island in the SF Bay was used that way during a similar time range.

Patrick says

Angel Island in the SF Bay was used that way during a similar time range.

Right, but you can't stay in these buildings overnight. In Sydney you can.

jazz_music says

OBAMA PLAGUE!

This was the Obama Plague; far deadlier to Americans.

Remember when multiple cruise ships were infested?


Also, remember how the Media consistently contextualized Ebola and didn't make it the only story on TV?

Merkel: Up to 70% of Germany could become infected
https://www.bbc.com/news/world-us-canada-51835856

CA containment seems to be working as NY and WA keep running away. Bay area has 168 total, SF just 18. Work from home works. Europe is new epicenter, Italy doing slowly better due to containment. Why Merkel doesn't do anything beats me.

mell says

Why Merkel doesn't do anything beats me.

She may be literally trying to kill off as many old Germans as possible.

She has already betrayed Germany completely by importing a million violent Muslim men.

Why would she not go further to destroy Germany? She has no children, she doesn't have a future.

Patrick says

mell says

Why Merkel doesn't do anything beats me.

She may be literally trying to kill off as many old Germans as possible.

She has already betrayed Germany completely by importing a million violent Muslim men.

Why would she not go further to destroy Germany? She has no children, she doesn't have a future.

Agreed but that's so obvious at some point they must revolt against that traitor. It's one thing to let things slip but to be so brazen and do nothing and come out saying shit like that. Well at least all the younger ones will build up immunity first lol. I mean the poor elderly literally nothing is done for them in Germany. Heartless.

Trump is certainly not to blame at all. His actions are decisive and rational.

mell says

Why Merkel doesn't do anything beats me.

We now know what Hillary would have done.

Fuuuuck... I'm starting to get refund requests for my Maui condo on VRBO. I clearly state no refund within 60 days of check-in and clearly recommend that they purchase travel insurance when they make the reservations. So far the 3 that are asking didn't get the travel insurance.

So far there are no flight cancellations or anything like that insurance would cover anyway...

What do you guys think I should do? Due to the contract I'm not at any obligation to return one cent.

If you stated it in listing fuck them.

jazz_music says

11,690 DEAD!!!

"Obama Plague; far deadlier to Americans."

Heheheh ... watch what happens 2020

Yes, let's. Which continents did Obama cut off from travel? Did major sporting leagues delay the season and cancel events?

This is 110% media driven.

just_dregalicious says

Fuuuuck... I'm starting to get refund requests for my Maui condo on VRBO. I clearly state no refund within 60 days of check-in and clearly recommend that they purchase travel insurance when they make the reservations. So far the 3 that are asking didn't get the travel insurance.

So far there are no flight cancellations or anything like that insurance would cover anyway...

What do you guys think I should do? Due to the contract I'm not at any obligation to return one cent.

I’m recovering, still don’t know if I had the Covid-19, and I probably never will know. I went to the ER for diagnosis yesterday but they said I wasn’t sick enough to be admitted, and they weren’t/couldn’t do a test. So i went home. The wife went to Costco business center which is where the restaurants go to stock up, and it was busy but not crazy busy. No water, TP, paper towels, rice, or beans left. But lots of other good stuff!
Stocked up on a gross of spaghetti noodles, macaroni noodles, flour, tomato sauce cans, and other non perishables. That’s all going in emergency stash.
Still not concerned about water. We have filtered water on the dam fridge! Why buy a million bottles? We got the emergency water sure, and 18,000 gallons in the swimming pool that could be boiled and drank in a pinch. Good enough.

Should have trainable, young crocodiles in that pool.

think you're smart because you buy macaroni instead of TP or toilet paper into the zombie apocalypse?

I'll invest in bullets as a hedge for VIX >80. Good luck w your tomatoe sauce though

Shaman says

Why buy a million bottles?

So that you can pollute Pacific with plastic waste. DUH!

Roughly 100 people - many very healthy - die per day in traffic across the US. So far 51 people died from the coronavirus. Maybe net net it's saving lives as many streets have become ghost towns, that should save at least 10 traffic deaths per day. Not to mention those causing lifelong injuries and disabilities.

mell says

Roughly 100 people - many very healthy - die per day in traffic across the US. So far 51 people died from the coronavirus. Maybe net net it's saving lives as many streets have become ghost towns, that should save at least 10 traffic deaths per day. Not to mention those causing lifelong injuries and disabilities.

Flu/cold season is already over in Southern US. Why close everything, other than getting orgasmic with PANIC!

Simo_Hayha says

Simo_Hayha

Häyhä in their alphabet soup language

good name tho

RC2006 says

If you stated it in listing fuck them.

Hahaha... You guys are meaner than me. I'm offering 50% back. Although partly because I don't want "He's a coronavirus meanie!" reviews to screw up my near perfect set so far.

https://widerimage.reuters.com/story/life-under-lockdown-wuhans-windows-balconies-and-rooftops?utm_source=patrick.net

Wuhan still underlockdown after 51 days.

NoCoupForYou says

Ebola and didn't make it the only story on TV?

Right and Ebola and Covid-19 are almost the same. Very similar rates of and means of transmission, and equally likely to grow out of control, and likelyhood of growing exponentially in the US

NOT !!

If they were all that similar, I guess the Obama team was way batter at stopping it it's tracks, than Trump's (fired in 2018) pandemic experts.

just_dregalicious says

RC2006 says

If you stated it in listing fuck them.

Hahaha... You guys are meaner than me. I'm offering 50% back. Although partly because I don't want "He's a coronavirus meanie!" reviews to screw up my near perfect set so far.

Shit, I didn't click submit earlier today. I was going to say the same regarding reviews. Reviews can sink a vacation rental overnight if you get a few bad ones. If it's not too late, I'd offer a credit for a future stay and try and keep all the cash.

Although I suppose not having to deal with a tenant/vacationer and still get any cash for it is pretty solid too. People are ass hoes is the only concern. You being gracious and giving 50% back is still gonna get people pissy. Tough call. Weird times.

One changed her mind and is flying out in a week. Seems like she's over her fear. The other was happy with the offer and the third I haven't heard back from yet.

marcus says

Right and Ebola and Covid-19 are almost the same. Very similar rates of and means of transmission, and equally likely to grow out of control, and likelyhood of growing exponentially in the US

You got that out of my comments? I contrasted the media's presentation.

Do H1N1 and Coronavirus, instead. The media also did not hype H1N1 like it did this Wu Ping Cough, though millions got it and it caused 11,000 deaths in the USA.

All this is hype is doing is further destroying the already low credibility of the News Media. In a few weeks, if bodies don't pile up in morgues, anybody who can be woken up will be awoken.

NoCoupForYou says

marcus says

Right and Ebola and Covid-19 are almost the same. Very similar rates of and means of transmission, and equally likely to grow out of control, and likelyhood of growing exponentially in the US

You got that out of my comments? I contrasted the media's presentation.

Do H1N1 and Coronavirus, instead. The media also did not hype H1N1 like it did this Wu Ping Cough, though millions got it and it caused 11,000 deaths in the USA.

All this is hype is doing is further destroying the already low credibility of the News Media. In a few weeks, if bodies don't pile up in morgues, anybody who can be woken up will be awoken.

It’s insane. Literally every agency was calling it the Wuhan corona virus but as soon as Trump says it, it’s xenophobic and racists and horrible.

The media is literally out of their minds with CNN and MSNBHeehaw leading the charge.

NoCoupForYou says

All this is hype is doing is further destroying the already low credibility of the News Media. In a few weeks, if bodies don't pile up in morgues, anybody who can be woken up will be awoken.

Everyone is woken. The hype will stop shortly. I hung out with 3 nurses last night. Their only concern was quality of care due to a massive amounts of people getting sick and flooding hospitals with patients. The virus itself is very benign and flu like.

Everyone is going to get this thing whether they know it or not, but we can't all get it at once is the concern. I personally disagree and would like to just drive down the street with a sprayer and get everyone infected so we could just be done with this and people build immunity.

That is actually being considered as the strategy in Britain:

https://www.theguardian.com/world/2020/mar/13/herd-immunity-will-the-uks-coronavirus-strategy-work

Patrick says

That is actually being considered as the strategy in Britain:

https://www.theguardian.com/world/2020/mar/13/herd-immunity-will-the-uks-coronavirus-strategy-work

It should be the only consideration. Mind you I have no immune or respiratory issues, so 100% biased. I don't think this goes away in 3-4 weeks when we attempt to start things back up to normal. In the meantime healthy people are losing jobs likely. Killing themselves. Some families that bust their ass but live pay check to pay check but don't live on the government teet will have trouble feeding themselves.

We are basically trying to protect old people from something that we cannot. It's pure stupidity. Just ban anyone that isn't a healthcare worker from interacting with the elderly. Specifically in nursing homes. That's the biggest issue in Washington. We get to the point of taking temperatures and shit and we'll end up putting people with colds in hospitals where they will likely get the virus when they wouldn't have.

Trump is handling this poorly in the opposite way most people would think. He should take the suck in up buttercup approach. Elderly, weak, immune compromised and respiratory issues just stay put and isolate instead of the whole fucking world. No different than peanut allergies. Understand you have an issue and adapt instead of expecting everyone else to upend their entire lives.

Chinese seems to be having some success in acute patients with chloroquine, an anti-malarial:

https://www.sciencedirect.com/science/article/pii/S0166354220301145?via%3Dihub

Poland is planning to use it:

https://www.reddit.com/r/Coronavirus/comments/fi8eox/poland_has_formally_registered_chloroquine_as_a/

It's related to the quinine of tonic water: https://en.wikipedia.org/wiki/Tonic_water

Maybe a gin and tonic is called for!