Ivermectin

▲
8
0
▼

Ivermectin

invite response
2021 May 9, 10:24pm 81,691 views 629 comments

https://sebastianrushworth.com/2021/05/09/update-on-ivermectin-for-covid-19/

Back in January I wrote an article about four randomized controlled trials of ivermectin as a treatment for covid-19 that had at that time released their results to the public. Each of those four trials had promising results, but each was also too small individually to show any meaningful impact on the hard outcomes we really care about, like death. When I meta-analyzed them together however, the results suddenly appeared very impressive. Here’s what that meta-analysis looked like:

It showed a massive 78% reduction in mortality in patients treated with covid-19. Mortality is the hardest of hard end points, which means it’s the hardest for researchers to manipulate and therefore the least open to bias. Either someone’s dead, or they’re alive. End of story.

You would have thought that this strong overall signal of benefit in the midst of a pandemic would have mobilized the powers that be to arrange multiple large randomized trials to confirm these results as quickly as possible, and that the major medical journals would be falling over each other to be the first to publish these studies.

That hasn’t happened.

Rather the opposite, in fact. South Africa has even gone so far as to ban doctors from using ivermectin on covid-19 patients. And as far as I can tell, most of the discussion about ivermectin in mainstream media (and in the medical press) has centred not around its relative merits, but more around how its proponents are clearly deluded tin foil hat wearing crazies who are using social media to manipulate the masses.

In spite of this, trial results have continued to appear. That means we should now be able to conclude with even greater certainty whether or not ivermectin is effective against covid-19. Since there are so many of these trials popping up now, I’ve decided to limit the discussion here only to the ones I’ve been able to find that had at least 150 participants, and that compared ivermectin to placebo (although I’ll add even the smaller trials I’ve found in to the updated meta-analysis at the end).

As before, it appears that rich western countries have very little interest in studying ivermectin as a treatment for covid. The three new trials that had at least 150 participants and compared ivermectin with placebo were conducted in Colombia, Iran, and Argentina. We’ll go through each in turn. ...

What we see is a 62% reduction in the relative risk of dying among covid patients treated with ivermectin. That would mean that ivermectin prevents roughly three out of five covid deaths. The reduction is statistically significant (p-value 0,004). In other words, the weight of evidence supporting ivermectin continues to pile up. It is now far stronger than the evidence that led to widespred use of remdesivir earlier in the pandemic, and the effect is much larger and more important (remdesivir was only ever shown to marginally decrease length of hospital stay, it was never shown to have any effect on risk of dying).

I understand why pharmaceutical companies don’t like ivermectin. It’s a cheap generic drug. Even Merck, the company that invented ivermectin, is doing it’s best to destroy the drug’s reputation at the moment. This can only be explained by the fact that Merck is currently developing two expensive new covid drugs, and doesn’t want an off-patent drug, which it can no longer make any profit from, competing with them.

The only reason I can think to understand why the broader medical establishment, however, is still so anti-ivermectin is that these studies have all been done outside the rich west. Apparently doctors and scientists outside North America and Western Europe can’t be trusted, unless they’re saying things that are in line with our pre-conceived notions.

And HCQ falls into that same bucket. Even worse - to admit HCQ works would be to admit Trump was right about something.

Liberals would rather that millions die than that Trump be allowed to be right about anything. They hate Trump more than they love their fellow humans.

« First « Previous Comments 242 - 281 of 629 Next » Last » Search these comments

242 DhammaStep 2021 Sep 16, 5:25pm

Started to feel sick today. Headache, sneezing, coughing, general fatigue, light and sound sensitivity. No loss of smell or taste though.

Even though I've had Covid, I immediately began the I-MASK+ protocol. Big thanks to all of you that pointed me in the right direction in obtaining the mectins. And Rin for the Quercetin Phytosome recommendation.

Now it's wait and see.

243

Maga_Chaos_Monkey 2021 Sep 16, 8:25pm

DhammaStep says

No loss of smell or taste though.

For me that was a week out after I was mostly recovering. I noticed when I was smoking some ribs. I couldn't smell the smoke. Thought I need to relight it until I SAW the smoke.

244

porkchopXpress 2021 Sep 16, 10:34pm

If he had the 'vid already, he may not even lose taste and smell. It also could be the flu or a cold or something else.

245

Patrick 2021 Sep 17, 9:42am

https://www.thegatewaypundit.com/2021/09/huge-uttar-pradesh-india-announces-state-covid-19-free-proving-effectiveness-deworming-drug-ivermectin/

Uttar Pradesh, India Announces State Is COVID-19 Free Proving the Effectiveness of “Deworming Drug” IVERMECTIN

246

Eric Holder 2021 Sep 17, 11:46am

Robert Sproul says

For anyone interested, I finally found a source for ‘mectin that is easy to navigate and with easy payment options. Not the cheapest prices, but not gouging Westerners like some sources seem to be set up to do. Pay with PayPal, as I did, or credit card instead of cumbersome bank transfer boondoggles. I ordered a full compliment of FLCCC recommended early treatment medications. Free shipping over 200 bucks. Response was within hours and order fulfillment in 1 day. Now I wait for 20-30 days for delivery. I will report at that time.
https://www.genericcures.com

@Robert Sproul

Did you also get separate e-mail with request to transfer money via paypal to what looks like private person's account? Was it this guy?

247 mell 2021 Sep 17, 12:02pm

@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

248

Eric Holder 2021 Sep 17, 12:02pm

mell says

@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

Thanks!

249 DhammaStep 2021 Sep 17, 12:04pm

DhammaStep says

Started to feel sick today. Headache, sneezing, coughing, general fatigue, light and sound sensitivity. No loss of smell or taste though.

Even though I've had Covid, I immediately began the I-MASK+ protocol. Big thanks to all of you that pointed me in the right direction in obtaining the mectins. And Rin for the Quercetin Phytosome recommendation.

Now it's wait and see.

Update: Feeling pretty good today. The mildest of headaches I don't even notice most of the time. All of the other symptoms are gone.

Dr. Pierre Kory and the FLCCC are courageous heroes as far as I'm concerned. They will be rewarded one way or another for their service to humanity, I am sure of it.

250

stereotomy 2021 Sep 17, 12:10pm

mell says

@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

Thanks for the info; I've had mine held up at JFK Customs since 9/1 (14 bidness days so far)

OTOH, my shipment from alldaypharmacy has already been delivered. Their stuff looks like doctors' pharma samples (1 pill in individual packaging as opposed to multiple pill blister packs). Manufacture date 6/21, so at least it's fresh.

EDIT: At least with PP, if customs confiscates I have recourse, unlike alldaypharmacy which is ACH.

251

Shaman 2021 Sep 18, 3:38pm

New website for buying human versions of Ivermectin. India based. Bit more expensive but seems legit!
https://www.riverpharmacy.ca/drug/invermectin

252

GNL 2021 Sep 18, 3:41pm

mell says

@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

How did you find out it was held up in customs?

253 mell 2021 Sep 18, 4:19pm

WineHorror1 says

mell says
@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

How did you find out it was help up in customs?

The company sends you a tracking number and website where you can track the package.

254 mell 2021 Sep 18, 4:22pm

stereotomy says

mell says
@Eric Holder yes same random dude paypal payment, was held 10 days at customs but they eventually released it and everything arrived. Looks like decent quality, a whole !covid! warchest will cost you $200-$300, worth it imo.

Thanks for the info; I've had mine held up at JFK Customs since 9/1 (14 bidness days so far)

OTOH, my shipment from alldaypharmacy has already been delivered. Their stuff looks like doctors' pharma samples (1 pill in individual packaging as opposed to multiple pill blister packs). Manufacture date 6/21, so at least it's fresh.

EDIT: At least with PP, if customs confiscates I have recourse, unlike alldaypharmacy which is ACH.

Yep I would have charged back my payment if it hadn't arrived, no matter the reason. They have a fat margin so they can eat a few charge backs. I'd assume the total production cost of a $300 order is no more than $20-$30. And that's probably still way too high cause they produce high volume.

255

Patrick 2021 Sep 19, 2:51pm

https://www.redvoicemedia.com/2021/09/india-state-that-pushed-ivermectin-now-free-of-active-covid-19-cases/

India State That Pushed Ivermectin Now Free of Active COVID-19 Cases
Ivermectin for the win?

256 Blue 2021 Sep 19, 4:56pm

Patrick says

https://www.redvoicemedia.com/2021/09/india-state-that-pushed-ivermectin-now-free-of-active-covid-19-cases/

India State That Pushed Ivermectin Now Free of Active COVID-19 Cases
Ivermectin for the win?

Its interesting that this is the largest state turned to right wing party during few years back. At the same time there is another state (Kerala - politically far left) with highest level of vaccine rates experiencing highest number of daily cases.
At personal level, I do hear people sense the horror show if they get in to hospitals, instead take Ivermectin when they experience any symptoms.

257

Patrick 2021 Sep 19, 5:04pm

@Blue That is indeed interesting.

The same basic dynamics are probably at work. A righteous and violently intolerant left claims to be open-minded, peaceful and tolerant.

They are typically the managerial and professional class which depends on suppressing critical thinking to keep their own positions. Too many questions = fired.

The poorer people, with a better grasp of reality and no need to lie to themselves or others to keep their jobs, if they even have jobs, correctly sees the jab as a threat to their lives and to their families. It's obvious to them, because they deal directly with corruption all the time and can easily recognize it.

I'm afraid that a lot of naive leftists are going to die directly due to their inability to recognize corruption.

258

GNL 2021 Sep 19, 5:11pm

Patrick says

I'm afraid that a lot of naive leftists are going to die directly due to their inability to recognize corruption.

I've got a long way to go to believe the overall death rate will be noticeably higher this winter.

259

Patrick 2021 Sep 23, 10:06am

https://www.thedesertreview.com/opinion/columnists/indias-ivermectin-blackout/article_e3db8f46-f942-11eb-9eea-77d5e2519364.html

One can see the bias in Wikipedia by going on the "talk" pages for each subject and reading about the fierce attempts of editors to add these facts and the stone wall refusals by the "senior" editors who have an agenda. And that agenda is not loyalty to your health.

The easy way to read the “talk” page on any Wikipedia subject is to click the top left “talk” button. Anyone can then review the editors’ discussions.

There is a blackout on any conversation about how Ivermectin beat COVID-19 in India. When I discussed the dire straits that India found itself in early this year with 414,000 cases per day, and over 4,000 deaths per day, and how that evaporated within five weeks of the addition of Ivermectin, I am often asked, "But why is there no mention of that in the news?"

Yes, exactly. Ask yourself why India’s success against the Delta variant with Ivermectin is such a closely guarded secret by the NIH and CDC. Second, ask yourself why no major media outlets reported this fact, but instead, tried to confuse you with false information...

260

Eric Holder 2021 Sep 23, 10:29am

WineHorror1 says

Patrick says
I'm afraid that a lot of naive leftists are going to die directly due to their inability to recognize corruption.

I've got a long way to go to believe the overall death rate will be noticeably higher this winter.

It will probably be lower, because of all the "pulled-up" deaths last year.

261

Patrick 2021 Sep 24, 10:10pm

https://openheart.bmj.com/content/8/1/e001655

Anti-inflammatory activity of ivermectin in late-stage COVID-19 may reflect activation of systemic glycine receptors

262

Patrick 2021 Sep 27, 9:43am

https://www.worldtribune.com/researchers-announce-ivermectin-should-be-used-globally-as-both-a-therapy-and-preventive-for-covid/

One study on treatment of “long haulers” out of the National University of San Marcos in Peru, which the authors write deserves further study. Administering ivermectin to patients who still had symptoms four to twelve weeks after their first onset, Peruvian doctors reported “in 87.9 percent of the patients, resolution of all symptoms was observed after 2 doses with an additional 7 percent reporting complete resolution after additional doses.”

263

GNL 2021 Sep 27, 10:17am

Patrick says

https://www.worldtribune.com/researchers-announce-ivermectin-should-be-used-globally-as-both-a-therapy-and-preventive-for-covid/

One study on treatment of “long haulers” out of the National University of San Marcos in Peru, which the authors write deserves further study. Administering ivermectin to patients who still had symptoms four to twelve weeks after their first onset, Peruvian doctors reported “in 87.9 percent of the patients, resolution of all symptoms was observed after 2 doses with an additional 7 percent reporting complete resolution after additional doses.”

If Ivermectin is the solution, how do we hold government and fauci et al accountable.

264

Shaman 2021 Sep 27, 10:26am

I’m thinking that for someone who is being forced to take the jab, going with the Johnson shot (viral vector) might be the best way, combined with the Rin supplement load and a healthy dose of Ivermectin. If the virus can’t propagate, it can’t deliver the death payload. Risky tho.

265 mell 2021 Sep 27, 10:31am

Shaman says

I’m thinking that for someone who is being forced to take the jab, going with the Johnson shot (viral vector) might be the best way, combined with the Rin supplement load and a healthy dose of Ivermectin. If the virus can’t propagate, it can’t deliver the death payload. Risky tho.

The Novavax vaxxine will be the least risky but it won't get approved before 2022. It delivers s-proteins into the body which is not optimal, but it's a finite number and it won't accumulate in organs such as with the mrna jabs where you cannot control the amount (and duration, possibly forever) and potential permanent dna changes. Also the adjuvants are natural and likely won't down-regulate innate immune responses like some of the mrna jabs. Since the s-protein itself is not harmless but usually well tolerated in those who catch a covid infection, a short protocol may still be preferred right after the shot. Of course the ADE concerns remain as with any jab.

266

Patrick 2021 Sep 27, 11:18am

Loads of evidence that ivermectin works:

https://covid19criticalcare.com/wp-content/uploads/2021/08/SUMMARY-OF-THE-EVIDENCE-BASE-FINAL.pdf

267

Shaman 2021 Sep 27, 11:31am

I doubt the Novavax will get an EUA. It can’t, not with the Pfizer jab getting FDA approval. That means it will be years before it’s available. I’m sure that this was done on purpose.

268 mell 2021 Sep 27, 11:34am

Shaman says

I doubt the Novavax will get an EUA. It can’t, not with the Pfizer jab getting FDA approval. That means it will be years before it’s available. I’m sure that this was done on purpose.

The current phase 3 is not for EUA if I understand correctly. They will apply for full approval by EOY. Similar to what Pfister did and is doing. They won't need years since Pfister didn't. Still they may try to delay it to sell more mrna poison but I think they will get full approval in 2022, the data so far is overwhelmingly better than Pfister and Moderna, and so is the safety profile. Also the who may fully approve it even before.

269

Patrick 2021 Sep 30, 11:36am

https://globalcovidsummit.org/news/biochemist-martenson-you-have-nothing-to-lose-with-ivermectin

Biochemist Martenson: You Have Nothing to Lose With Ivermectin
SEP 29, 2021
Biochemist Chris Martenson argues that using Ivermectin off-label for COVID19 is both safe and effective.

His rationale is simple:

Safe. This proven drug has been used hundreds of millions of times worldwide for decades; It is safe and well-tolerated.

Effective. Prominent metanalyses have determined a strong signal, including randomized controlled trials and numerous observational studies by physicians like us.
Those who disparage Ivermectin as mere “horse dewormer” probably aren’t doctors. Physicians worldwide have been using the Nobel-prize-winning drug successfully in treating COVID-19.

Martenson compares the inexpensive off-patent Ivermectin to on-patent and EUA-approved Remdisivir, which comes with “25% severe side-effects.” So as Martenson concludes, the “safety profiles aren’t even remotely comparable.”

Such prompts one to ask why the FDA has approved Remdisivir for emergency use and not Ivermectin.

Even if it turns out, whether in further study or considered against new variants, that Ivermectin is less effective or ineffective, Martinsen essentially concludes that given how inexpensive the drug is:

What have you got to lose?

COVID19 physicians continue to emphasize early treatment, which might well include Ivermectin.

270

Eric Holder 2021 Sep 30, 12:01pm

Makes me wonder if ivermectin would work against other viruses, like common flu.

271

zzyzzx 2021 Oct 2, 3:54pm

272

Shaman 2021 Oct 2, 5:11pm

mell says

The current phase 3 is not for EUA if I understand correctly. They will apply for full approval by EOY. Similar to what Pfister did and is doing. They won't need years since Pfister didn't. Still they may try to delay it to sell more mrna poison but I think they will get full approval in 2022, the data so far is overwhelmingly better than Pfister and Moderna, and so is the safety profile. Also the who may fully approve it even before.

I really really hope you are totally right on this!
A Novavax option would remove a key part of the vax stranglehold the sociopathic Democrats have on america.

273

RWSGFY 2021 Oct 2, 5:17pm

zzyzzx says

Ivermectin is a generic now. I doubt Merck even makes it anymore.

274

Patrick 2021 Oct 2, 10:38pm

https://www.zerohedge.com/covid-19/pfizer-launches-final-study-covid-drug-thats-suspiciously-similar-ivermectin

Pfizer Launches Final Study For COVID Drug That's Suspiciously Similar To 'Horse Paste'
BY TYLER DURDEN
TUESDAY, SEP 28, 2021 - 06:58 AM

Another piece US anti-Ivermectin puzzle may have emerged. On Monday, Pfizer announced that it's launching an accelerated Phase 2/3 trial for a COVID prophylactic pill designed to ward off COVID in those may have come in contact with the disease.

Coincidentally (or not), Pfizer's drug shares at least one mechanism of action as Ivermectin - an anti-parasitic used in humans for decades, which functions as a protease inhibitor against Covid-19, which researchers speculate "could be the biophysical basis behind its antiviral efficiency."

Lo and behold, Pfizer's new drug - which some have jokingly dubbed "Pfizermectin," is described by the pharmaceutical giant as a "potent protease inhibitor."

275